- Renal and Vascular Pathologies
- Cerebrovascular and Carotid Artery Diseases
- Vasculitis and related conditions
- Animal Nutrition and Physiology
- Cardiovascular Health and Disease Prevention
- Intracranial Aneurysms: Treatment and Complications
- Vascular Procedures and Complications
- Clinical Laboratory Practices and Quality Control
- Vitamin D Research Studies
- Alcohol Consumption and Health Effects
- Acute Kidney Injury Research
- Blood Pressure and Hypertension Studies
- Meat and Animal Product Quality
- Growth Hormone and Insulin-like Growth Factors
- Birth, Development, and Health
- Peripheral Artery Disease Management
- Pancreatic function and diabetes
- Rabbits: Nutrition, Reproduction, Health
- Metabolomics and Mass Spectrometry Studies
- Cardiovascular Function and Risk Factors
- Hormonal Regulation and Hypertension
- Traditional Chinese Medicine Studies
- Aquaculture Nutrition and Growth
- Aortic aneurysm repair treatments
- Chronic Kidney Disease and Diabetes
University of Molise
2023-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2024
First Affiliated Hospital of Zhengzhou University
2016-2024
National Center for Clinical Laboratories
1999-2024
Peking University People's Hospital
2024
Peking University
2024
Yantaishan Hospital
2021-2024
Feed Research Institute
2023
Northwest Women's and Children's Hospital
2022-2023
Fujian Inspection and Research Institute for Product Quality
2018-2023
Kidney is one of the most vulnerable organs in sepsis, resulting sepsis-associated acute kidney injury (SA-AKI), which brings about not only morbidity but also mortality sepsis. Ferroptosis a new kind death type cells elicited by iron-dependent lipid peroxidation, participates pathogenesis The aim this study was to verify occurrence ferroptosis SA-AKI and demonstrate that post-treatment with irisin could restrain alleviate via activating SIRT1/Nrf2 signaling pathway. We established model...
Previously we reported on severe vitamin D deficiency in a large-scale cohort the Tangshan area northern China. However, whether is associated with cardiovascular risk factors has not been systematically examined cohort.We aimed to determine correlation between serum status and lipid levels circulation via an observational study.Serum 25-hydroxyvitamin (25[OH]D) was measured. Based measurement subjects were classified into quintiles. Dyslipidemia defined as having one of following: elevated...
<h3>Background</h3> Gait speed modulation is impaired in manifest Huntington's disease (mHD) due to reduced stride length. Speed impairments and their functional correlates have not been examined prodromal HD (pHD). <h3>Aims</h3> (1) To examine (stride length-cadence relationship) pHD mHD; (2) evaluate the association between mobility. <h3>Method</h3> We tested 20 (mean = 41.75 y), 19 mHD 44 controls 42.45 y). Experiment I (internal cues): subjects walked at self-selected preferred, fast,...
Abstract Puerarin has been reported to be an excellent antioxidant, anti-inflammatory and antimicrobial agent, but the potential effect of puerarin on porcine epidemic diarrhea virus (PEDV) is unclear. This study aimed determine whether could alleviate intestinal injury in piglets infected with PEDV. A PEDV (Yunnan province strain) infection model was applied 7-day-old at 10 4.5 TCID 50 (50% tissue culture infectious dose). Piglets were orally administered dosage 0.5 mg/kg body weight from...
The study investigated the effects of rearing system and carcase weight on meat quality Nero d'Aspromonte pigs. Thirty-three barrows, aged between 14 16 months with an average slaughter body approximately 140 160 kg, were randomly selected among 80 pigs reared two different systems, indoor or plein air. Carcase was recorded dressing percentage calculated. Longissimus thoracis (LT) muscles sampled grouped into: air low weight; high weight. Proximate composition, cholesterol, vitamin E fatty...
China has enacted subnational smoke-free legislations, which requires compliance evaluations to provide data for future implementation planning. This study comprehensively assessed regulation in Xining Western China. Conducted November and December 2023, the used a mixed-methods design. Quantitative surveys of observing existence 'no evidence smoking' were completed by trained investigators 1007 venues (including 2553 indoor 55 outdoor areas). PM2.5 concentration assessments smoking...
The taste and aroma quality the price of tea are largely impacted by geographical origin harvest season.
The purpose of the present study was to determine impact alcohol consumption on incidence hypertension.A total 32,389 male coal mine workers from Kailuan Coal Group in northern China (Kailuan study), free hypertension, myocardial infarction, stroke, transient ischemia attack and cancer, were followed up every 2 years for 4 years. average intake during past year reported as baseline.During follow-up, 9151 out developed hypertension categorically. At end cumulative relation daily alcoholic...
Cathelicidin-related antimicrobial peptide (CRAMP), peptide, was reported to protect against myocardial ischemia/reperfusion injury. In the pathology of diabetic cardiomyopathy, endothelial-to-mesenchymal transition (EndMT) results from hyperglycemia-induced endothelial injury, leading cardiac fibrosis. This study aims evaluate effect CRAMP on EndMT and fibrosis mice heart. Mice were subjected streptozotocin induce diabetes. administered by intraperitoneal injection (1 or 8 mg/kg/d) for 4...
This study was performed to explore the effect of aortic arch type on technical indicators in patients undergoing carotid artery stenting (CAS).The data 224 consecutive who underwent unilateral CAS from January 2011 December 2012 were retrospectively analyzed. The requirement for placement guiding catheter into common with assistance an angiographic catheter, fluoroscopy time, contrast agent dose, and adverse events recorded.The time significantly longer dose higher Type III than I II...
Salinomycin is a polyether antiprotozoal antibiotic that widely used as an animal food additive. Some antifungal, antiparasitic, antiviral and anti‑inflammatory activities have been reported for salinomycin. Recently, the anti‑cancer effect of salinomycin has demonstrated in breast cancer; however, underlying mechanism remains unknown. The present study aimed to investigate functional roles progression prostate cancer cells using DU145 PC‑3 cell lines. Western blotting reverse...
The present study aimed to test the synbiotic PoultryStar® solUS delivered in ovo evaluate its effect on hatchability, productive performance and meat quality, compared post-hatch administration water. On twelfth day of embryonic incubation, 1200 fertile eggs were divided into groups injected with 2 mg/embryo (T1) 3 (T2), a saline group physiological an uninjected control (C). After hatching, 120 male chicks/group reared chicks from supplemented via drinking water (T3). Hatchability was low...
The aim of this study was to evaluate the safety and efficacy percutaneous transluminal angioplasty (PTA) for symptomatic pulmonary stenosis in Takayasu arteritis (TA).From January 2009 December 2012, clinical data 14 patients [mean age 33.9 ± 9.3 yrs; 11 female (78.6%)] with TA underwent PTA were analyzed prospectively.PTA successfully performed 22 lesions patients. Among those lesions, 18 treated by alone while others stent implantation. Three (21.4%) had reperfusion injury; 2 recovered...
β-Conglycinin (β-CG), an anti-nutritional factor, is a major allergen in soybeans to induce intestinal dysfunction and diarrhea neonatal animals, including piglets human infants. This study with piglet model determined the effects of N-acetylcysteine (NAC) on function autophagy response β-CG challenge. Twenty-four 12-day-old (3.44 ± 0.28 kg), which had been weaned at 7 days age adapted for 5 after weaning, were randomly allocated control, β-CG, + NAC groups. Piglets control group fed liquid...
In recent years, the free-range system for laying hens has increased, driven by societal sensitivity to animal welfare. This study aimed comparatively analyze total lipid, cholesterol, and fatty acid composition of egg yolks late-age reared in enriched cages (C) (FR). Eggs were collected from Lohmann Brown Classic at 68th, 70th, 72nd, 74th week age. The concentrations lipids cholesterol not affected (p > 0.05) either factor. Egg yolk FR group showed lower < 0.01) monounsaturated acids...
Doxorubicin- (DOX-) induced cardiomyocyte loss results in irreversible heart failure, which limits the clinical applications of DOX. Currently, there are no drugs that can effectively treat DOX-related cardiotoxicity. Follistatin-like 1 (FSTL1) has been reported to be a transforming growth factor-beta-inducible gene, and FSTL1 supplementation attenuated ischemic injury cardiac apoptotic mice. However, effect on DOX-induced cardiomyopathy not elucidated. We aimed explore whether could prevent...
Accurate diagnosis is critical to both therapeutic decisions and prognostication in interstitial lung diseases (ILD). However, surgical biopsies carry high complication rates. Fibred confocal fluorescence microscopy (FCFM) offers an alternative as it can visualize tissue vivo at the cellular level with minimal adverse events. We wanted investigate diagnostic utility, safety of using FCFM for patients ILD.In suspected ILD, images were obtained from multiple bronchopulmonary segments a...