A5102896629- Hepatocellular Carcinoma Treatment and Prognosis
- RNA modifications and cancer
- Liver Disease Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Cancer, Lipids, and Metabolism
- Circular RNAs in diseases
- Epigenetics and DNA Methylation
- Inflammatory Biomarkers in Disease Prognosis
- Liver Diseases and Immunity
- Liver Disease and Transplantation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Plant Reproductive Biology
- Ferroptosis and cancer prognosis
- FOXO transcription factor regulation
- Hepatitis B Virus Studies
- Liver physiology and pathology
- Cancer, Hypoxia, and Metabolism
- Plant Molecular Biology Research
- Cancer-related gene regulation
- Kruppel-like factors research
- Inflammatory mediators and NSAID effects
- Cancer-related Molecular Pathways
- Amoebic Infections and Treatments
- Vitamin D Research Studies
Beijing Forestry University
2022-2025
Hunan First Normal University
2023-2025
Chongqing University
2018-2024
Chongqing Three Gorges Central Hospital
2024
Xi'an Jiaotong University
2011-2024
Shaanxi Provincial Hospital of Traditional Chinese Medicine
2021-2024
Northeastern University
2024
Yulin University
2023-2024
Affiliated Zhongshan Hospital of Dalian University
2024
Second Affiliated Hospital of Xi'an Jiaotong University
2024
Recent evidence shows that long non-coding RNAs (lncRNAs) are closely related to hepatogenesis and a few aggressive features of hepatocellular carcinoma (HCC). Increasing studies demonstrate lncRNAs potential prognostic factors for HCC. Moreover, several reported the combination predicting overall survival (OS) HCC, but results varied. Thus, more effort including accurate statistical approaches is needed exploring value in HCC.To develop robust lncRNA signature associated with HCC recurrence...
Abstract DNA replication is a central procedure of cell proliferation, whereas aberrant indicated to be driving force oncogenesis. Minichromosome maintenance complex component 7 (MCM7) plays an essential role in initiating replication. To investigate the potential oncogenic properties and prognostic value MCM7 hepatocellular carcinoma (HCC), we conducted immunohistochemistry staining 153 HCC samples found that high expression level was associated with worse overall survival (OS) patients....
Pancreatic cancer (PC) is a highly fatal disease worldwide and often misdiagnosed in its early stages. The exploration of novel non-invasive biomarkers will definitely benefit PC patients. Recently, circulating miRNAs body fluids are emerging as for diagnosis. In this study, we first conducted comprehensive robust rank aggregation (RRA) analysis based on 21 published miRome profiling studies. We statistically identified clinically validated miRNA expression pattern These consisted four...
Rationale: For intravascular stent implantation to be successful, the processes of vascular tissue repair and therapy are considered critical. However, mechanisms underlying eventual fate smooth muscle cells (VSMCs) during remains elusive. In this study, we hypothesized that M2 macrophage-derived exosomes mediate cell-to-cell crosstalk induce dedifferentiation phenotypes in VSMCs. Methods:In vivo, 316L bare metal stents (BMS) were implanted from left iliac artery into abdominal aorta...
Quercus acutissima Carruth. is a Chinese important energy plant with high ecological and economic values. While the species chloroplast genome has been reported, its mitochondrial (mitogenome) still unexplored. Here, we assembled annotated Q. mitogenome, compared characteristic differences several closely related species. The mitogenome’s main structure branched three distinguished contigs (linear molecule 1, circular 2, 3) 448,982 bp total length 45.72% GC content. mitogenome contained 51...
// Yue Teng 1, * , Yan Zhang 2, Kai Qu 3, Xinyuan Yang 1 Jing Fu Wei Chen 3 Xu Li 2 Department of Obstetrics and Gynecology, The First Affiliated Hospital Xi'an Jiaotong University, 710061, China Center for Translational Medicine, Hepatobiliary Surgery, These authors have contributed equally to this work Correspondence to: Li, e-mail: lixuxjtu@126.com Keywords: epithelial ovarian cancer, Warburg effect, microRNA, miR-29b, AKT Received: April 11, 2015 Accepted: September 14, Published:...
Pretreatment nutritional and immunological statuses play an indispensable role in predicting the outcome of patients with various types malignancies. The purpose this study is to evaluate predictive value albumin/globulin ratio (AGR) overall survival (OS) recurrence hepatocellular carcinoma (HCC) following radical hepatic carcinectomy.This retrospective included a total 172 HCC complete medical follow-up information between 2002 2012. AGR was calculated according formula: = albumin/globulin....
In order to realize the automatic identification of typical defects in transmission lines, a defect method for lines based on You Only Look Once (YOLO)v5 algorithm is proposed, which has advantages low missing detection rate and false rate. Firstly, line image dataset constructed three defects: bird's nest defect, insulator shakeproof hammer corresponding labeling strategy formulated according characteristics. Secondly, this paper introduces network structure YOLOv5 detail. For sake further...
Non-small cell lung cancer (NSCLC) is the most common and cause of cancer-related mortality globally. Increasing evidence suggested that long non-coding RNAs (lncRNAs) were involved in death. To explore possible prognostic lncRNA biomarkers for NSCLC patients, present study, we conducted a comprehensive profiling analysis based on 1902 patients from Gene Expression Omnibus (GEO) The Cancer Genome Atlas (TCGA) datasets. In discovery phase, employed 682 combination four GEO datasets (GSE30219,...
The preparation of right-side-out-orientated coupling-driven ROS-sensitive nanoparticles on the inner leaflet cell membrane for positively regulating phenotypic conversion in atherosclerosis.
The development of clinically accessible biomarkers is critical for the early diagnosis gastric cancer (GC) in patients. High-throughput proteomics techniques could not only effectively generate a serum peptide profile but also provide new approach to identify potentially diagnostic and prognostic In this study, we aim discriminating GC. discovery cohort, screened potential using magnetic-bead-based purification matrix-assisted laser desorption/ionization time-of-flight mass spectrometry 64...
Accumulating evidence highlights the fact that long non‑coding RNAs (lncRNAs) serve as critical factors in growth of hepatocellular carcinoma (HCC). The dysregulation lncRNA KCNQ1 opposite strand/antisense transcript 1 (KCNQ1OT1) has been reported numerous human benign diseases. However, role KCNQ1OT1 HCC remains poorly understood. In this study, we demonstrated expression was abnormally increased tissues. ectopic high associated with liver cirrhosis, a larger tumor size, an advanced TNM...
The establishment of hybrid cell membrane-camouflaged nanotherapeutics is crucial to preserve and impart their biological functionality inherited from the source cells. In this study, one side relies on intrinsic affinity between intracellular domain Band 3 in red blood cells membrane (Rm) P4.2 peptide-modified nanoparticles (Rm-Que/Cu), promoting self-assembly coupling-driven encapsulation Rm surface nanodrugs. On other side, it involves integrating bioengineered with high Del-1 expression...