A5103124156- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatitis Pathology and Treatment
- Cancer Genomics and Diagnostics
- Renal cell carcinoma treatment
- Gallbladder and Bile Duct Disorders
- Radiomics and Machine Learning in Medical Imaging
- Neuroendocrine Tumor Research Advances
- Pediatric Hepatobiliary Diseases and Treatments
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Vascular Malformations and Hemangiomas
- Gastric Cancer Management and Outcomes
- Gastrointestinal disorders and treatments
- MRI in cancer diagnosis
- RNA modifications and cancer
- Cancer Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Colorectal and Anal Carcinomas
- Advanced Radiotherapy Techniques
- Pancreatic function and diabetes
- Glioma Diagnosis and Treatment
Shanghai Jiao Tong University
2017-2024
Ruijin Hospital
2014-2024
State Key Laboratory of Oncogene and Related Genes
2020-2023
Shanghai Institute of Hematology
2015
Nanfang Hospital
2004
Southern Medical University
2004
Robot-assisted pancreaticoduodenectomy (RPD) has been reported to be safe and feasible. As a new technique, RPD learning curve similar that of other types minimally invasive pancreatic surgery such as laparoscopic pancreaticoduodenectomy. To our knowledge, no reports exist on the outcomes open (OPD) after curve.To analyze evaluate actual advantages RPD.Between May 2010 December 2018, 450 patients underwent in Shanghai Ruijin Hospital affiliated with Jiaotong University Shanghai, China,...
We aimed to describe our experience and the learning curve of 450 cases robot-assisted pancreaticoduodenectomy (RPD) optimize surgical process so that findings can be useful for surgeons starting perform RPD.Robotic systems were first introduced 20 years ago. Pancreaticoduodenectomy (PD) is a challenging surgery because its technical difficulty. RPD may overcome some these difficulties.The medical records patients who underwent between May 2010 December 2018 at Shanghai Ruijin Hospital...
Abstract Background Robotic-assisted minimally invasive surgery is associated with worse oncologic outcomes for some but not other types of cancers. We conducted a propensity score-matched analysis to compare robotic-assisted laparoscopic (RPD) vs. open pancreatoduodenectomy (OPD) pancreatic ductal adenocarcinoma (PDAC). Methods Treatment-naïve PDAC patients undergoing either RPD or OPD at our hospital between January 2013 and December 2017 were included. Propensity score matching was ratio...
Pancreatoduodenectomy is a complex and challenging procedure that requires meticulous tissue dissection proficient suturing skills. Minimally invasive surgery with the utilization of robotic platforms has demonstrated advantages in perioperative patient outcomes retrospective studies. The development pancreatoduodenectomy (RPD) specific progressed significantly, since first reported 2003, high-volume centers pancreatic are reporting large series improved pain management reduced length stay....
Objective: To assess short-term and long-term outcomes following robotic enucleation (REn) of tumors in the proximal pancreas. Background: Despite advantages preserving function via pancreatic enucleation, controversies persist, since this can be associated with severe complications, such as clinically relevant postoperative fistula, especially when performed near main duct. The safety efficacy REn context remain largely unknown. Methods: A retrospective analysis was all patients who...
Abstract Background As a tissue‐sparing procedure, pancreatic enucleation has become an alternative for benign or borderline tumours; it been proved to be safe and feasible. To date, large sample size of robotic not reported. This study aimed discuss the clinical evaluation postoperative complications after compare with open surgery. Methods Patients who underwent during December 2010–December 2014 at Shanghai Ruijin Hospital, affiliated Jiaotong University School Medicine in China, were...
This study aimed to compare the short-term outcomes of open and robotic-assisted distal pancreatectomy (ODP RDP) for benign low-grade malignant tumors.The patients who underwent RDP ODP or pancreatic tumors at our center were included. After PSM a 1:1 ratio, perioperative variations in two cohorts compared.After PSM, 219 cases recorded. The cohort showed advantages operative duration [120 (90-150) min vs 175 (130-210) min, P < 0.001], estimated blood loss [50 (30-175) ml 200 (100-300) ml,...
Robotic surgery is the most advanced minimally invasive technique for treatment of complicated solid pseudopapillary tumors (SPT). The aim this study to evaluate feasibility robotic SPTs in pancreatic head. A retrospective analysis clinical data 83 head was conducted. Clinical characteristics were extracted and propensity score matching (PSM) used compare mid-term outcomes two techniques. Pancreaticoduodenectomy (PD), duodenum-preserving partial resection (DPPHR-P) tumor enucleation (En)...
We aimed to develop a nomogram predict the survival and prognosis of adenosquamous carcinoma pancreas (ASCP).
Abstract Background High body mass index was considered as a risk factor for minimally invasive surgery. The short‐term outcomes of robot‐assisted pancreaticoduodenectomy (RPD) remain controversial. This study aims to investigate the feasibility and advantage RPD in patients with high compared open (OPD). Methods Clinical data 304 who underwent from January 2016 December 2019 Ruijin Hospital, Shanghai Jiao Tong University School Medicine collected. Patients BMI >25 kg/m 2 were included...
Background: Total pancreatectomy (TP) is a complex surgical procedure with significant postoperative morbidity. Despite the narrowed range of indications for TP, introduction neoadjuvant chemotherapy and increasing complexity resections performed in high-volume centers has increased number annually TPs, especially regarding malignant disease. The robotic-assisted pancreatic surgery provided novel minimally invasive approach yet feasibility this technique still unknown. This study assessed...
Background: The significance of surgical resection in the treatment metastatic pancreatic ductal adenocarcinoma (PDAC) is currently unclear. This study aimed to summarize and clarify experience M1 PDAC our center evaluate whether it may offer benefits some patients. Methods: We analyzed data patients with who underwent synchronous tumor between 2003 2014 at Ruijin Hospital. Simultaneously, clinical for palliative bypass or exploratory laparotomy only was also collected during same period as...
Pre-mRNA processing factor 40 homolog A (PRPF40A) is an important protein involved in pre-mRNA splicing and expressed a variety of cell types. However, the function PRPF40A pancreatic cancer remains unclear. Therefore, our study to investigate role pathogenesis cancer.We extracted expression data clinical information from different online databases, including Cancer Genome Atlas (TCGA), Oncomine Gene Expression Omnibus (GEO). Subsequently, samples were collected patients validate gene using...
Inositol polyphosphate 4-phosphatase type II (INPP4B), a member of the PI3K/Akt signaling pathway, plays vital role in initiation and progression cancers. However, its biological pancreatic cancer remains largely undiscovered. Our study aimed to investigate effects INPP4B on proliferation clinical relevance.INPP4B expression data were obtained from The Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO) databases. Clinicopathological survival retrieved TCGA database. CCK8 colony...
Pancreatic cancer is a highly aggressive featured by early metastasis and multiple chemoresistance. Surgical resection remains the only way for radical cure of pancreatic cancer. The aim this study was to assess safety, feasibility oncological effect Heidelberg TRIANGLE operation in total pancreatectomy (TP) borderline resectable (BRPC).Patients with BRPC eligible TP were selected underwent operation. Sharp dissection applied separate tumor involved artery. Then we completely dissected soft...
Objectives: The optimal number of the examined lymph nodes (ELNs) in pancreaticoduodenectomy for pancreatic ductal adenocarcinoma has been widely studied. However, accuracy nodal positivity patients with inadequate lymphadenectomy is still unclear. purpose our study was to determine positive reported 1-3 and probability that 4 or more could be along tumor size examined. Methods: We obtained data on who underwent resectable diagnosed during 2004-2013 from US Surveillance, Epidemiology, End...
Abstract Objective To compare the short‐term and long‐term outcomes between robot‐assisted middle pancreatectomy (RMP) distal (RDP). Methods From August 2010 to May 2018, more than 800 patients were diagnosed with benign or low‐grade malignant pancreatic tumours. According inclusion criteria, a total of 164 included in our study. Among them 123 received RMP 41 RDP spleen‐preserving. These divided into two groups, propensity score matching (PSM) was used minimize bias. Short‐term recorded...
There are few reports about the survival rate of patients with pancreatic adenosquamous cancer (PASC). This study evaluated and analyzed prognostic factors resectable (rPASC), which might fulfill blank in research PASC. In this study, we identified 55 who were diagnosed rPASC from January 2013 to May 2019 at Pancreatic Disease Center Shanghai Ruijin Hospital affiliated Jiaotong University School Medicine. Age, sex, BMI, tumor position, other important demographic data collected analyzed. The...