The COVID-19 pandemic at its peak compelled students to stay home and adapt the distance learning system. world has gone through phases of fear respite in recent years. There have been a number studies related student via online teaching during pandemic. Now, as vaccination coverage picks up appears achieved plateau, it is time take view students’ perceptions effectiveness skill development This study assesses preferences regarding offline post-COVID-19 lockdown with resumption classes. A...

Diabetes is the most common cause of end-stage renal disease, also called kidney failure. The link between artery receptor angiotensin II type I (AT1R) and endothelin-1 (ET-1), involved in vasoconstriction, oxidative stress, inflammation fibrosis (collagen) diabetes-induced nephropathy with without metformin incorporation has not been previously studied. (type 2) was induced rats another group started (200 mg/kg) treatment 2 weeks prior to induction diabetes continued on until being culled...

University students are more likely to experience mental disorders. This study aimed assess the prevalence of depression, anxiety, and stress among health non-health university at King Khalid students, Abha, Kingdom Saudi Arabia. An anonymous validated short form Arabic questionnaire scale (DASS-21) survey was distributed online on social media platforms through face-to-face interview for 1700 from March 1st May 31st 2024. A multivariate linear regression model used examine relationships...

Health care providers can use these virtual platforms for delivering medical advice and prescriptions to patients. This study was aimed explore the patients’ experiences level of satisfaction regarding health received during coronavirus disease-19 (COVID-19) pandemic. also assessed before lockdown sleep quality in participants. The current included 522 participants from Saudi Arabia. Virtual questionnaire implemented record data on patient experience toward COVID-19 Patients expressed a high...

Autism spectrum disorder (ASD) is a collective neurodevelopmental affecting young children and accounting for 1% of the world’s population. The cerebellum major part human brain affected by ASD associated with substantial reduction in number Purkinje cells. An association between expression nitrosative stress biomarker inducible nitric oxide synthase (iNOS), as well glycogen deposition damaged cells, has not been previously reported medical literature. To explore this correlation, rats were...

Knowledge, attitudes, and practices (KAP) of the general population toward Marburg Virus Disease (MVD) have a crucial impact on control prevention strategies, particularly during outbreaks. The current study aimed to develop, culturally adapt, validate questionnaire for assessing KAP MVD (EKAP-MVD). A cross-sectional using face-to-face interview an anonymous online survey was conducted from March 13 April 28, 2023 in 8 Sub-Saharan African countries (Ethiopia, Ghana, Kenya, Lesotho, Nigeria,...

Growing evidence suggests that feeding practices in early childhood play a major role the occurrence of diarrhea. However, there is lack information regarding and its relationship with occurrences diarrhea young children from Saudi Arabia. The present study aimed to measure prevalence assess among between two months years age A cross-sectional was carried out large cities Aseer region southwest total 302 mothers attending well-baby clinics across six primary health centers were included....

Abstract Background COVID-19 preventive measures required a drastic shift to online teaching-learning in most of countries. Institutions used different combinations live lectures (synchronous) requiring students attend the class real-time, as well recorded uploaded by instructors be accessed per their own convenience (asynchronous). We undertook this study assess and compare perceptions regarding learning experiences synchronous versus asynchronous mode instruction using during compulsory at...

Vaccines are an important part of the COVID-19 pandemic response plan. This cross-sectional study aims to assess attitude and perception levels parents toward vaccines for children aged 0-18 years in Aseer region Saudi Arabia. Data were analyzed using SPSS version 16.0. Out a total 1463 parents, 30.6% assumed that vaccination may be more dangerous than adults. Nearly 36.5% don't have any concern about children's vaccination. About 12.8% not received vaccination, 55% some sort hesitation...

Replication Factor C Subunit 4 (RFC4), an oncogene implicated in many human cancers, has yet to be extensively studied cancer types determine its expression patterns and tumor tissue function. Various bioinformatics tools were used analyze RFC4 as a potential therapeutic target across cancers. We first examined levels several relationships with grade, stage, metastasis, patient survival. also RFC4’s genetic changes, epigenetic methylation, effect on microenvironment (TME) immune cell...

Currently, doxorubicin (DOX) is one of the medications commonly used in chemotherapy to treat different types tumors.Nonetheless, despite being effective multiple tumors, yet its use limited owing cytotoxic effects, therapeutic DOX has been limited. This work aimed explore whether curcumin (CMN) can prevents DOX-induced cardiotoxicity rats. Four groups rats were created, with first functioning as a control, while second group received CMN. alone was administered third group, whereas CMN and...

Vaccines are an important part of the COVID-19 pandemic response plan. This study was undertaken to find out percentage supporters in Saudi population for vaccination among children, and assess population's perceptions towards children.This nationwide adopted a cross-sectional survey adult participants, conducted by trained medical students. The anonymous questionnaire published on social media tools. Statistical analysis using two-tailed tests.Six hundred twenty (620) participants were...

Choosing a future medical speciality is considered one of the most critical challenges for undergraduate students worldwide. The present study assessed influences and factors related to career choices in Saudi Arabia. was designed cross-sectional manner collect data from all interns Kingdom Arabia 5 months, starting September 2021 ending January 2022. questionnaire completed by 1725 aged 18 30 with mean age 24.2 ± 4.6 years, 64.6% were females. In all, 50.4% respondents reported that they...

The chance of survival rate and autophagy smooth muscle cells under calcium stress were drastically improved with a prolonged inclusion Lycopene in the media. results showed an viability from 41% to 69% reduction overall autophagic bodies 7% 3%, which was well agreement LC3II III mRNA levels. However, proliferation slow compared controls. fall major inflammatory marker TNF-α antioxidant enzyme GPx regarded as significant restoration markers cell survival. reactive oxygen species (ROS)...

Lower extremity arterial disease (LEAD) is a major risk factor for amputation in diabetic patients. The advanced glycation end products (AGEs)/endothelin-1 (ET-1)/nitric oxide synthase (NOS) axis-mediated femoral artery injury with and without metformin has not been previously investigated. Type 2 diabetes mellitus (T2DM) was established rats, another group of rats treated two weeks 200 mg/kg metformin, before being induced T2DM. latter cohort were continued on until they sacrificed at week...

Autism spectrum disorder (ASD) is a neurodevelopmental condition that affects young children in social relatedness and communication besides other characteristics. A community's awareness early intervention services diagnosing treating autistic are essential for preventing the expected complications, eg language delay, interaction, intellectual ability.To assess parent's knowledge perceptions regarding autism its associated clinical features effects.A cross-sectional study was conducted...

<h3>Objectives:</h3> To investigate the presence of toxoplasmosis, rubella, cytomegalovirus, and herpes (TORCH) infections in women attending at antenatal care clinic Abha, Kingdom Saudi Arabia (KSA). <h3>Methods:</h3> A total 190 blood samples were collected from Abha maternity hospital Aseer region, KSA, February 2018 to May 2019 screened with TORCH panel (toxoplasmagondii [IgG/IgM], cytomegalovirus [CMV] rubella simplex type 1 2 [IgG/IgM]). <h3>Results:</h3> The mean age was 31.42±6.514...

Depression is a common comorbidity in children and adolescents with type 1 diabetes mellitus (T1DM), yet its prevalence, impact, intervention strategies remain underexplored. This study aims to assess the prevalence of depression among T1DM, investigate impact on health outcomes, explore potential strategies. A convenient sampling method was employed recruit 229 participants aged 6 18 years from single center. Data collection involved validated assessments, demographic surveys,...