A5030348186- Pregnancy and Medication Impact
- Zoonotic diseases and public health
- Animal Disease Management and Epidemiology
- Reproductive System and Pregnancy
- Diagnosis and treatment of tuberculosis
- Viral Infections and Vectors
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Pregnancy and preeclampsia studies
- COVID-19 epidemiological studies
- HIV-related health complications and treatments
- Viral Infections and Outbreaks Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Pregnancy-related medical research
- Virus-based gene therapy research
- Infection Control and Ventilation
- Preterm Birth and Chorioamnionitis
- Herpesvirus Infections and Treatments
- Tuberculosis Research and Epidemiology
- Bone and Joint Diseases
- Reproductive tract infections research
- IL-33, ST2, and ILC Pathways
- Cultural Industries and Urban Development
- Syphilis Diagnosis and Treatment
Columbia University
2020-2023
EcoHealth Alliance
2020-2023
Duke-NUS Medical School
2018-2019
As a leading global city with high population density, Singapore is at risk for the introduction of novel biological threats. This has been recently reinforced by human epidemics in SARS coronavirus, 2009 pandemic H1N1 influenza A virus, and enterovirus 71. Other major threats to include MERS-coronavirus various avian swine viruses. The ability quickly identify robustly track such initiate an early emergency response remains significant challenge. In effort enhance respiratory virus...
<h3>Importance</h3> The association of elevated levels specific inflammatory markers during pregnancy with adverse birth outcomes and infant growth could indicate pathways for potential interventions. <h3>Objective</h3> To evaluate whether higher certain are associated preterm (PTB), low weight (LBW), deficits. <h3>Design, Setting, Participants</h3> In this cohort study pregnant women or without HIV, 218 mother-infant pairs were followed up from through 12 months post partum June 27, 2016,...
A number of serious human adenovirus (HAdV) outbreaks have been recently reported: HAdV-B7 (Israel, Singapore, and USA), HAdV-B7d (USA China), HAdV-D8, -D54, -C2 (Japan), HAdV-B14p1 (USA, Europe, HAdV-B55 (China, France).To understand the epidemiology HAdV infections in we studied 533 HAdV-positive clinical samples collected from 396 pediatric 137 adult patients Singapore 2012 to 2018. Genome sequencing phylogenetic analyses were performed identify genotypes, clonal clusters, recombinant or...
There is an increasing body of evidence suggesting that transmission respiratory viruses occurs through the inhalation virus-laden particles. Our study describes use aerosol sampling system to monitor prevalence airborne in a hospital setting. Using SKC AirCheck Touch pumps, with National Institute for Occupational Safety and Health (NIOSH) bioaerosol samplers filter cassette blanks, 28 samples were collected ward Singapore. Following DNA/RNA extraction, real-time RT-PCR/PCR was used...
Background Recent studies in adults have characterized differences systemic inflammation between with and without latent tuberculosis infection (LTBI+ vs . LTBI−). Potential by LTBI status has not been assess pregnant women. Methods We conducted a cohort study of 155 LTBI+ 65 LTBI− women, stratified HIV status, attending an antenatal clinic Pune, India. was assessed interferon gamma release assay. Plasma used to measure markers using immunoassays: IFN β , CRP, AGP, I-FABP, γ IL-1 soluble...
Objective: There are limited studies on the association of HIV infection with systemic inflammation during pregnancy. Design: A cohort study ( N = 220) pregnant women 70) (all antiretroviral therapy) and without 150) were enrolled from an antenatal clinic in Pune, India. Methods: The following inflammatory markers measured plasma samples using immunoassays: soluble CD163 (sCD163), CD14 (sCD14), intestinal fatty acid-binding protein (I-FABP), C-reactive (CRP), alpha 1-acid glycoprotein (AGP),...
The increasing global emergence of zoonoses warrants improved awareness activities that predispose vulnerable communities to greater risk disease. Zoonotic disease outbreaks regularly occur within Myanmar and at its borders partly due insufficient knowledge behavioral risks, hindering participatory surveillance reporting. This study employed a strategy among high-risk populations understand the risks for zoonotic transmission in an effort identify factors pathogen spillover. To explore...
Abstract Background Interactions between humans and animals are the key elements of zoonotic spillover leading to disease emergence. Research understand high-risk behaviors associated with transmission at human-animal interface is limited, few consider regional local contexts. Objective This study employed an integrated behavioral–biological surveillance approach for early detection novel known viruses in potentially populations, effort identify risk factors determine potential foci...
Bacterial vaginosis (BV) is a highly prevalent disorder of the cervicovaginal microbiota. Molecular-BV may put women at increased risk for adverse reproductive and obstetric outcomes. We investigated association HIV pregnancy on vaginal microbiota associations with molecular-BV in age from Pune, India.
In pregnant women, studies are lacking on the relationship of vegetable and animal flesh (poultry, red meat seafood) intake with inflammation, especially in low- middle-income countries. We conducted a cohort study women receiving antenatal care at BJ Medical College Pune, India. The dietary was queried third trimester using validated food frequency questionnaire. Twelve inflammatory markers were measured plasma samples immunoassays. Only 12% population vegetarians, although levels lower...