A5050467547- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- Advanced Chemical Sensor Technologies
- Mass Spectrometry Techniques and Applications
- Chromatography in Natural Products
- Biochemical Analysis and Sensing Techniques
- Food Quality and Safety Studies
- Neuroscience and Neuropharmacology Research
- Seaweed-derived Bioactive Compounds
- Berberine and alkaloids research
- Natural product bioactivities and synthesis
- Cancer-related gene regulation
- Dye analysis and toxicity
- Cancer therapeutics and mechanisms
- Tryptophan and brain disorders
- Phytochemicals and Antioxidant Activities
- Plant-based Medicinal Research
- Alkaloids: synthesis and pharmacology
- Traditional Chinese Medicine Analysis
- Pharmacogenetics and Drug Metabolism
- Pharmacological Effects and Assays
- Metabolism and Genetic Disorders
- Epigenetics and DNA Methylation
- Quinazolinone synthesis and applications
- Nephrotoxicity and Medicinal Plants
Ewha Womans University
2024
Kyung Hee University
2012-2018
RATIONALE Alkaloids with significant therapeutic effects are the main active constituents of Corydalis ( C .) species. There several kinds alkaloids in . species associated diverse alkaloid metabolism plants, but they rarely identified. This study aimed to identify by liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI‐MS/MS). METHODS Several types were extracted from using ultrasonication 70% CH 3 OH, and extract was partitioned at pH 2 12. Separation achieved C18...
Rapid determination of SCFAs in rat fecal samples by GC-MS/MS combined with <italic>in situ</italic> extraction and derivatization.
RATIONALE HM781‐36B (1‐[4‐[4‐(3,4‐dichloro‐2‐fluorophenylamino)‐7‐methoxyquinazolin‐6‐yloxy]‐piperidin‐1‐yl]prop‐2‐en‐1‐one hydrochloride) is a new anticancer drug to treat advanced solid tumors in clinical trial. In order understand the behavior of vitro and vivo we validated an analytical method for its major metabolites plasma. METHODS metabolism was studied dog plasma, urine feces as well using human liver microsomes with extraction by ethyl acetate or methyl tert ‐butyl ether,...
Anthocyanins ( ACs ) and flavonoids were isolated from three different berry species (blueberry, black chokeberry, cranberry) via high‐speed counter‐current chromatography HSCCC ). A total of 19 9 in extracts characterized using LC‐ESI‐MS / MS . The spectra produced a commonly abundant [M‐gluc] + ion due to the easy cleavage glycosidic ether bond, which is directly reflected structural information aglycon moiety linked glucose. Among identified , major compounds as glycosylated with 3‐ O...