A5057549183- Dermatologic Treatments and Research
- Skin Protection and Aging
- Facial Rejuvenation and Surgery Techniques
- Dermatology and Skin Diseases
- Botulinum Toxin and Related Neurological Disorders
- Cancer and Skin Lesions
- Nail Diseases and Treatments
- Hair Growth and Disorders
- Body Contouring and Surgery
- melanin and skin pigmentation
- Dental Implant Techniques and Outcomes
- Allergic Rhinitis and Sensitization
- Cutaneous lymphoproliferative disorders research
- Acne and Rosacea Treatments and Effects
- Bone Tissue Engineering Materials
- Genetic and rare skin diseases.
- Electrochemical sensors and biosensors
- Asthma and respiratory diseases
- Nonmelanoma Skin Cancer Studies
- Advancements in Transdermal Drug Delivery
- Ginseng Biological Effects and Applications
- Wound Healing and Treatments
- Metabolomics and Mass Spectrometry Studies
- Biochemical Analysis and Sensing Techniques
- Photodynamic Therapy Research Studies
Chung-Ang University Hospital
2019-2025
Chung-Ang University
2015-2025
Chungnam National University
2021-2024
Seoul National University
2007-2023
Seoul National University Hospital
2020-2023
National University College
2022
New Generation University College
2020-2022
Konkuk University
2018-2021
University of Georgia
2020
Jeju National University
2020
Idiopathic pulmonary fibrosis (IPF) is a progressive, eventually fatal disease characterized by of the lung parenchyma and loss function. IPF believed to be caused repetitive alveolar epithelial cell injury dysregulated repair process including uncontrolled proliferation (myo) fibroblasts excessive deposition extracellular matrix proteins in interstitial space; however, pathogenic pathways involved have not been fully elucidated. In this study, we attempted characterize metabolic changes...
Various kinds of functional cosmetics are on the market, although there a variety opinions concerning actual effect. Transdermal microneedle patch has been introduced as newly developed device for drug delivery through skin.This study was conducted to verify face skin improvement effect and safety novel cosmetic patch.A total 84 Korean females finished this prospective clinical trial. The subjects were divided into 3 groups: (1) soluble hyaluronic acid (HA) alone, (2) HA plus adenosine...
Previously, we found that osteogenic responses to zirconia co-doped with niobium oxide (Nb 2 O 5 ) or tantalum (Ta are comparable titanium, which is widely used as a dental implant material. The present study aimed evaluate the in vitro potential of hydroxyapatite (HA)-coated by an aerosol deposition method for improved osseointegration. Surface analysis scanning electron microscopy and x-ray diffraction proved thin as-deposited HA film on showed shallow, regular, crater-like surface....
Numerous fillers are increasingly used for augmentation of volume loss and relaxation facial wrinkles. Collagen stimulators the latest next-generation dermal that can induce neocollagenesis. To investigate biophysical characteristics, safety, efficacy newly developed polydioxanone (PDO) filler in comparison with poly-l lactic acid (PLLA) polycaprolactone (PCL) fillers.In vitro assay, morphology particles, rheological property were measured. A total 24 female hairless mice (SKH1-Hrhr )...
Metabolic rewiring has been recognized as an important feature to the progression of cancer. However, essential components and functions lipid metabolic networks in breast cancer are not fully understood. In this study, we investigated roles altered metabolism malignant phenotype Using a spheroid-induced epithelial-mesenchymal transition (EMT) model, conducted multi-layered lipidomic transcriptomic analysis comprehensively describe lipidome during transformation. A tremendous homeostatic...
Background Afzelin, a flavonoid (kaempferol 3-O-α-L-rhamnopyranoside) isolated from Thesium chinense , is known for its potent anti-inflammatory properties. However, effects on the molecular aspects of inflammation and lipogenesis in SZ95 sebocytes has not been investigated. Objective This study aimed to (i) investigate inflammatory sebum secretion changes when Cutibacterium acnes -treated immortalized human sebocyte cell line (SZ95) exposed particulate matter (PM) (ii) examine afzelin...
Deoxycholic acid (DCA) at a concentration of 10 mg/mL is commonly used for localized fat reduction, but its application in larger areas like the upper arm can lead to higher costs and discomfort. Diluting DCA may provide cost-effective solution with reduced pain while still maintaining efficacy. This case series aims evaluate efficacy, safety, overall cost-effectiveness diluted injections concentrations 5 2.5 reduction. Four healthy adult females received subcutaneous either or DCA,...
To better understand the respiratory lipid phenotypes of asthma, we developed a novel method for profiling bronchoalveolar lavage fluid (BALF) using HPLC-QTOF-MS with an internal spectral library and high-throughput lipid-identifying software. The was applied to BALF from 38 asthmatic patients (18 nonsteroid treated bronchial asthma [NSBA] 20 steroid [SBA]) 13 healthy subjects (NC). We identified 69 lipids, which were categorized into one six classes: lysophosphatidylcholine (LPC),...
Abstract Background Noninvasive skin‐tightening devices have become increasingly popular in response to increasing demand for improvements skin laxity and tightening with minimal risk recovery time. Objective We evaluated the efficacy safety of HIFU face body. Methods A total 32 Korean subjects enrolled this prospective clinical trial. The were treated both cheeks, lower abdomen, thigh. Skin elasticity was measured before after treatment using a Cutometer (CT575, Courage Khazaka ® , Cologne,...
The onset of osteoporosis leads to a gradual decrease in bone density due an imbalance between formation and resorption. To achieve optimal drug efficacy with minimal side effects, targeted delivery the is necessary. Previous studies have utilized peptides that bind hydroxyapatite, mineral component bone, for bone-targeted delivery. In this study, hydroxyapatite binding (HAB) tag fused 30Kc19α-Runt-related transcription factor 2 (RUNX2) bone-targeting. This recombinant protein can penetrate...
Demand for noninvasive body contouring has increased.We evaluated the efficacy and safety of a thermal high-intensity focused ultrasound (HIFU) device abdominal shaping.Adults with mass index ≤30 kg/m an subcutaneous fat tissue thickness ≥2.5 cm were enrolled HIFU treatment at energy levels 150 J/cm (first session) 135 (second session). The primary end point was change from baseline waist circumference post-treatment Week 8. Secondary points were: changes in weight, waist/hip ratio, assessed...
Objective To assess the effect of core strengthening exercises on Cobb angle and muscle activity in male college students with functional scoliosis. Methods Static dynamic back were evaluated via surface electromyography (sEMG). A exercise protocol comprising 18 was performed three times/week for 10 weeks. Patients randomly allocated to either a home- or community-based programme. Cervical thoracolumbar scans sEMG after Results total 87 underwent cervical scans. Of these, 53 abnormal...
There is an increasing interest in skin rejuvenation using hyaluronic acid (HA) fillers beyond the improvement of deep wrinkles and volume deficiencies, which have been primary research foci past. We conducted a pilot study sample six middle-aged male subjects. Using automatic intradermal injector with 0.020 mL material contained each injection point total 100 points, 2 non-cross-HA filler was injected into entire face at every treatment session. administered injections HA for three sessions...
Vascular compromise with impending skin necrosis is one of the most serious potential complications. Early recognition vascular occlusion and swift aggressive treatment are required to avoid any irreversible changes. However, initial symptoms a event often dismissed as simple post-procedural discomfort. If more than 3 days pass after filler injection, crust formation initiated over erythematous base along rim fibrous tissue. Due replacement normal tissues by material, healing process may...
ABSTRACT Objectives: To investigate the association between periodontal soft tissue, alveolar bone and dental parameters surrounding incisors at baseline in patients with skeletal Class III malocclusion. Materials Methods: The study sample comprised 154 teeth from 28 malocclusion (19 men 9 women, 21.15 ± 4.02 years). Periodontal tissue examination hard measurements cone-beam computed tomography (CBCT) were performed. Factor analysis was used to reduce CBCT variables, correlation factors...
There is a tremendous demand for dermal rejuvenation with minimal invasiveness and patient downtime.In this study, we evaluated the performance of nonfractional monopolar radiofrequency improvement photoaged skin texture wrinkles.In total, 32 6-week-old female hairless mice were randomized into four groups eight each: (a) healthy control, (b) UVB-exposed, (c) UVB + microneedling, (d) microneedle RF. After applying each treatment modality, surface was globally investigated histologically...