A5021166268- Gastrointestinal motility and disorders
- Traditional Chinese Medicine Studies
- Pharmacological Effects of Natural Compounds
- Helicobacter pylori-related gastroenterology studies
- Geological and Geochemical Analysis
- Medical Research and Treatments
- Inflammatory Bowel Disease
- Infant Health and Development
- Hydrocarbon exploration and reservoir analysis
- Geothermal Energy Systems and Applications
- Acupuncture Treatment Research Studies
- Geochemistry and Geologic Mapping
- Ginseng Biological Effects and Applications
- MicroRNA in disease regulation
- Circular RNAs in diseases
- CO2 Sequestration and Geologic Interactions
- Complementary and Alternative Medicine Studies
- Cancer-related molecular mechanisms research
- Mycobacterium research and diagnosis
- Gut microbiota and health
- Plant-derived Lignans Synthesis and Bioactivity
- Metabolism, Diabetes, and Cancer
- Biochemical Analysis and Sensing Techniques
- Ion Transport and Channel Regulation
- Pathogenesis and Treatment of Hiccups
Capital Medical University
2014-2024
Beijing Hospital of Traditional Chinese Medicine
2013-2024
Institute of Hydroecology
2018-2024
Central Geological Survey, MOEA
2024
Electric Power Research Institute
2024
Tianjin University
2017-2019
Beijing Hospital
2015-2019
Nanjing Agricultural University
2014-2017
Wuxi People's Hospital
2016
Nanjing Medical University
2016
Dysregulated microRNAs (miRNAs/miRs) directly modulate the biological functions of gastric cancer (GC) cells and contribute to initiation progression GC. MiR-17-5p runt-related transcription factor 3 (RUNX3) have been reported be related GC progression; however, specific interaction between miR-17-5p RUNX3 in require further investigation. Western blotting, real-time PCR immunohistochemistry were used study expression level tissues plasma. The function was examined by measuring cell...
Inflammatory bowel disease (IBD) is a refractory disorder characterized by chronic and recurrent inflammation. The progression pathogenesis of IBD closely related to oxidative stress irregularly high concentrations reactive oxygen species (ROS). A new oxidation-responsive nano prodrug was constructed from phenylboronic esters-modified carboxylmethyl chitosan (OC-B) conjugated with berberine (BBR) that degrades selectively in response ROS. optimized micelles exhibited well-controlled...
Abstract Ulcerative colitis (UC), a chronic and nonspecific inflammatory disease of the intestine, has become prevalent global health concern. This guideline aims to equip clinicians caregivers with effective strategies for treatment management adult UC patients using traditional Chinese medicine (TCM). The systematically evaluated contemporary evidence through Grading Recommendations Assessment, Development, Evaluation framework. Additionally, it incorporated insights from ancient medical...
Hot dry rock (HDR) is a kind of clean energy with significant potential. Since the 1970s, United States, Japan, France, Australia, and other countries have attempted to conduct several EGS (Enhanced Geothermal System) projects extract thermal by breaking through key technologies. However, up now, development HDR still in research, development, demonstration stage. An exploration borehole (with 236°C at depth 3705 m) was drilled into Triassic granite Gonghe Basin northwest China 2017....
Chinese herbal medicine (CHM) has been used in China and some other countries for the treatment of patients with functional dyspepsia (FD). However, controlled studies supporting efficacy such treatments FD are lacking. In this trial, we aimed to assess safety modified LiuJunZi decoction spleen-deficiency qi-stagnation syndrome.We performed a randomized, double-blind, placebo-controlled trial from five centers. Patients syndrome (n = 160) were randomly assigned groups given CHM or placebo...
Abstract In high-altitude tectonic regions, significant geothermal activity influences groundwater arsenic levels, presenting crucial resource and environmental challenges. The present study examines the Gonghe-Guide Basin located in northeastern region of Qinghai-Tibet Plateau. employs a comprehensive approach encompassing field sampling, hydrochemical analysis, thermodynamic modeling, statistical analysis to ascertain composition origins groundwater. research data indicates that area...
Two single nucleotide polymorphisms (SNPs) in the human SLCO1B1 gene, c.388A>G (rs2306283) and c.521T>C (rs4149056), are independent determinants of efficacy side effects statin drugs. Multinational clinical guidelines...
Background . Chinese herbal medicine (CHM) has been used in China and elsewhere to treat patients with functional dyspepsia (FD). However, controlled studies supporting the efficacy of such treatment are lacking. Objective To assess safety modified Ban xia xie xin decoction FD cold heat complexity syndrome. Methods We performed a randomized, double-blind, placebo-controlled trial involving from five centers. Patients syndrome<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Abstract Hot dry rock (HDR) is an important geothermal resource and clean energy source that may play increasingly role in future management. High‐temperature HDR resources were recently detected deep regions of the Gonghe Basin on northeastern edge Tibetan Plateau, which led to a significant breakthrough exploration China. This research analyzes temperature distribution, radiogenic heat production, flow, crustal thermal structure Qiaboqia Valley, Guide Plain, Zhacanggou area based borehole...
Abstract Background In Traditional Chinese Medicine (TCM) theory, functional dyspepsia (FD) can be divided into different syndromes according to clinical symptoms and signs, the most common one is spleen-deficiency qi-stagnation syndrome that treated by traditional patent medicine ---- two kinds of Zhizhu pills, between which primary difference in ingredients contains immature orange fruit Citrus aurantium L.(IFCA) other sinensis Osbeck (IFCS). The trial's objective was compare efficacy...
Gastric cancer is a leading cause of death worldwide. In-depth research precancerous lesions gastric carcinoma (PLGC) with malignant transformation potential key measure to prevent the development carcinoma. Recently, calycosin has been shown have anticancer effects in vitro and vivo. The molecular mechanism by which affects PLGC, however, not yet elucidated. purpose this study was evaluate effect N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced PLGC rats.The mucosa rats were evaluated...
Myristicin is a type of natural compound showing anti-proliferative, anti-microbial, and anti-inflammatory effects. However, its role in gastric cancer treatment remains unknown.In this study, the effect myristicin on as well underlying mechanism was investigated.Human cells were exposed to various concentrations (0, 7.8125, 15.625, 31.25 μM) for 48 h. Then CCK-8, fluorescence-activated cell sorting, Hoechst staining performed evaluate proliferation apoptosis. The levels proteins associated...
Background Ulcerative colitis (UC) impairs the health-related quality of life (HRQOL). The difference in HRQOL between patients with mild and moderately active UC is not well-defined. Few studies have been conducted to explore factors that influence Chinese patients. Our study aims were (1) compare mildly moderate patients; (2) UC; (3) analyze demographic disease characteristics China. Methods A total 110 114 enrolled. recorded. was measured by version inflammatory bowel questionnaire (IBDQ)...