A5026582417- Knowledge Management and Sharing
- Technology Adoption and User Behaviour
- Online Learning and Analytics
- Online and Blended Learning
- Digital Marketing and Social Media
- Innovative Teaching and Learning Methods
- Recommender Systems and Techniques
- Transportation Planning and Optimization
- Open Education and E-Learning
- Advanced Text Analysis Techniques
- Educational Technology and Assessment
- Fibroblast Growth Factor Research
- Health Literacy and Information Accessibility
- Collaboration in agile enterprises
- Pharmacological Effects of Natural Compounds
- Social Media in Health Education
- Innovation and Knowledge Management
- Higher Education and Teaching Methods
- ERP Systems Implementation and Impact
- Traditional Chinese Medicine Studies
- Environmental and Agricultural Sciences
- Pulmonary Hypertension Research and Treatments
- Advanced Technologies in Various Fields
- Advanced Computational Techniques and Applications
- Paraquat toxicity studies and treatments
Tongji University
2015-2024
Hubei University of Medicine
2015-2023
Renmin Hospital of Wuhan University
2022-2023
Wuhan University
2005-2023
First Affiliated Hospital of Jinan University
2023
Second Affiliated Hospital of Zhejiang University
2023
Harbin Institute of Technology
2022
Weatherford College
2020
Hubei Provincial Hospital of Traditional Chinese Medicine
2018-2019
Lanzhou Army General Hospital
2018
AbstractAlthough E-Learning 2.0 has played a significant role in training and development within the organisational environment, after an initial acceptance, its use is frequently discontinued. Prior studies offered insights into participation E-Learning; however, there limited research on continuance intention towards systems contexts. Furthermore, most widely used models, such as technology acceptance model (TAM), neglect interactive social processes 2.0. Therefore, this study proposes...
In practice, online health communities have passed the adoption stage and reached diffusion phase of development. this phase, patients equipped with knowledge regarding issues involved in care are capable switching between different to maximize their community activities. Online employ doctors answer patient questions, high quality more likely be acknowledged by patients. Therefore, factors that motivate maintain ongoing relationships must addressed. However, has received limited scholarly...
Icariin, a major active ingredient in traditional Chinese medicines, is attracting increasing attention because of its unique pharmacological effects against ischaemic heart disease. The histone deacetylase, sirtuin-1, plays protective role ischaemia/reperfusion (I/R) injury, and this study was designed to investigate the icariin models cardiac I/R injury elucidate potential involvement sirtuin-1.
Abstract Although some studies have explored massive open online courses (MOOCs) discussion forums and MOOC reviews separately, of both aspects are insufficient. Based on the theory self-determination, this paper proposes research hypotheses that learning progress has a direct impact an indirect influence through social interactions in forums, as well. Coursera largest platform, is selected empirical object, data from learners who participated forum provided August 2016 to December 2019...
Paraquat (PQ), as a highly effective and nonselective herbicide, induces cell apoptosis through generation of superoxide anions which forms reactive oxygen species (ROS).Mitochondria, regulators for cellular redox signaling, have been proved to play an important role in PQ-induced apoptosis.This study aimed evaluate whether how mitochondrial fission interacts with oxidative stress mouse alveolar type II (AT-II) cells.Firstly, we demonstrated that PQ promoted release cytochrome-c...
// Bing Wu 1,* , Lu Yu 2,* Yishi Wang 3,* Hongtao Chen Li 3 Yue Yin 3,4 Jingrun Yang Zhifa Qiangsun Zheng 1 and Heng Ma Department of Cardiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China 2 Pathology, Xijing Physiology, School Basic medicine, 4 Pathophysiology, * These authors have contributed equally to this work Correspondence to: Ma, email: Zheng, Keywords : aging, ALDH2, autophagy, carbonyl stress, SIRT1, Gerotarget Received September 10, 2015 Accepted December...
Open innovation communities (OICs) can help enterprises make full use of external knowledge resources from users, but problems such as low user participation and conversion rate creative ideas impact the efficiency OICs. Most studies on this topic employ qualitative or empirical methods a static perspective, ignore effect interaction between users well cumulative time. A discussion dynamic evolution process open is lacking. Based review literature OICs, performance, system dynamics, study...
Hepatic fibrosis (HF) is a chronic hepatic pathological process induced by various liver injuries, with few available therapies. Previous research studies revealed that HF characterized the accumulation of excess extracellular matrix in liver, mainly overexpressed activated stellate cells (HSC). Therefore, HSC have been targeted clinical trials for management HF. The aim present study was to develop an anti-HF drug delivery system acrylic resin (Eudragit® RS100, Eud RS100) nanoparticles...
Background . Chinese herbal medicine (CHM) has been used in China and elsewhere to treat patients with functional dyspepsia (FD). However, controlled studies supporting the efficacy of such treatment are lacking. Objective To assess safety modified Ban xia xie xin decoction FD cold heat complexity syndrome. Methods We performed a randomized, double-blind, placebo-controlled trial involving from five centers. Patients syndrome<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
The significance of associations between bone mineral density (BMD) and atherosclerosis in the Asian population is less clear. aim this study was to explore population-level BMD subclinical atherosclerosis. This a community-based cross-sectional conducted Shenyang, China. A total 385 Chinese women men aged 37–87 years were studied. measured at hip lumbar spine using dual-energy x-ray absorptiometry. ankle-brachial index (ABI), pulse wave velocity (PWV), carotid intima-media thickness (CIMT)...
Mitochondrial fission is critically involved in cardiomyocyte apoptosis, which has been considered as one of the leading causes ischaemia/reperfusion (I/R)-induced myocardial injury. In our previous works, we demonstrate that aldehyde dehydrogenase-2 (ALDH2) deficiency aggravates apoptosis and cardiac dysfunction. The aim this study was to elucidate whether ALDH2 promotes mitochondrial injury death response I/R stress underlying mechanism. induced by aortic cross-clamping for 45 min....
Sepsis is a systemic inflammatory syndrome induced by several infectious agents. Multiple organs are affected sepsis, including the liver, which plays an important role in metabolism and immune homeostasis. Fibroblast growth factors (FGFs) participate biological processes, although of FGF5 sepsis unclear.In this study, lipopolysaccharide (LPS) was administrated to mice establish sepsis-induced liver injury. A similar vitro study conducted using L-02 hepatocytes. Western blot...
In the MOOCs context, learners experience information overload. Thus, it is necessary to improve personalized recommendation algorithms for learners. The current algorithm focuses mainly on learners’ course ratings. However, choice of courses not only based interests and preferences. It also affected by knowledge domains learning capabilities, all which change dynamically over time. Therefore, this study proposes a hybrid combining clustering with collaborative filtering. First, data rating...
In heart disease, transforming growth factor-β1 (TGF-β1) converts fibroblasts into myofibroblasts, which synthesize and secrete fibrillar type I III collagens. The purpose of the present study was to investigate how hydrogen sulfide (H2S) suppresses TGF-β1-induced differentiation human cardiac myofibroblasts. Human were serum-starved in fibroblast medium for 16 h before exposure TGF-β1 (10 ng mL-1) 24 with or without sodium hydrosulfide (NaHS, 100 µmol L-1, 30 min pretreatment) treatment....
As the E-Learning 2.0 system is a tool to help members manage knowledge in an effective way, this study attempts verify constructs of creation self-efficacy, subjective norms, perceived usefulness, organizational climate, attitudes toward sharing and intention engage sharing. A sample 284 participants from companies China that have already implemented systems participated study. Structural equation modeling conducted test research hypotheses. Research results show (1) Knowledge usefulness...
Mechanical pressure overload and other stimuli often contribute to heart hypertrophy, a significant factor in the induction of failure. The UDP-glucose ceramide glycosyltransferase (UGCG) enzyme plays crucial role metabolism sphingolipids through production glucosylceramide. However, its hypertrophy remains unknown. In this study, UGCG was induced response vivo phenylephrine stimulation vitro. Additionally, downregulation ameliorated cardiomyocyte improved mitochondrial oxidative stress,...