A5037917977- Shoulder Injury and Treatment
- Tendon Structure and Treatment
- Orthopedic Surgery and Rehabilitation
- Sports injuries and prevention
- Immunotherapy and Immune Responses
- Aluminum Alloys Composites Properties
- Fungal Infections and Studies
- Spinal Hematomas and Complications
- Bone Tissue Engineering Materials
- Cytokine Signaling Pathways and Interactions
- Knee injuries and reconstruction techniques
- Infectious Diseases and Mycology
- Vibrio bacteria research studies
- Neurogenetic and Muscular Disorders Research
- Listeria monocytogenes in Food Safety
- Bone fractures and treatments
- Antifungal resistance and susceptibility
- Bone health and osteoporosis research
- Veterinary Equine Medical Research
- Hip and Femur Fractures
- Shoulder and Clavicle Injuries
- Spine and Intervertebral Disc Pathology
- Bacterial biofilms and quorum sensing
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
Kumamoto University
2014-2025
The effects of fibroblast growth factor 2 (FGF-2) on healing after surgical repair chronic rotator cuff (RC) tears remain unclear.FGF-2 enhances tenogenic response, leading to biomechanical and histological improvement repaired RC in rats.Controlled laboratory study.Adult male Sprague-Dawley rats (n = 117) underwent unilateral surgery refix the supraspinatus tendon its insertion site 3 weeks detachment. Animals were assigned either FGF-2 group or a control group. assessed via tests at...
Operative treatment is an option for fractures when the fracture unstable or patient wishes to return early daily life social activities. Metal plates such as titanium and stainless steel are often used in surgery, but metal plate lacks bone-healing activity not bioabsorbable, requiring a second surgery remove it after bone union. Here we show that magnesium (Mg) made from alloy of yttrium, zinc, aluminum with main component long-period stacking ordered structure promotes formation rabbit...
A multipotent cell population co-expressing a basic-helix-loop-helix transcription factor scleraxis (Scx) and SRY-box 9 (Sox9) has been shown to contribute the establishment of entheses (tendon attachment sites) during mouse embryonic development. The present study aimed investigate involvement Scx + /Sox9 cells in postnatal formation fibrocartilaginous healing process after injury, using ScxGFP transgenic mice. We demonstrate that are localized layers at insertion site supraspinatus tendon...
Osteosarcoma is rare but the most common bone tumor. Diagnostic tools such as magnetic resonance imaging development of chemotherapeutic agents have increased survival rate in osteosarcoma patients, although 5-year has plateaued at 70%. Thus, new treatment approaches needed. Here, we report that IL-17, a proinflammatory cytokine, increases mortality mouse model with AX cells. cell transplantation into wild-type mice resulted 100% due to ectopic ossification and multi-organ metastasis....
BackgroundzzListeria monocytogenes (L.monocytogenes) is a rare causative pathogen of brain abscess that often found in immunocompromised patients.Although patients with supratentorial listerial abscesses showed longer survival surgical drainage, the standard therapy for subtentorial lesions has not been established.Case ReportzzWe report herein patient supra-and caused by L. infection.These did respond to antibiotics, and his symptoms gradually worsened.Drainage was indicated lesions,...
When ruptured, ligaments and tendons have limited self-repair capacity rarely heal spontaneously. In the knee, Anterior Cruciate Ligament (ACL) often ruptures during sports activities, causing functional impairment requiring surgery using tendon grafts. Patients with insufficient time to recover before resuming risk re-injury. To develop more effective treatment, it is necessary define mechanisms underlying ligament repair. For this, animal models can be useful, but mice are too small create...
Lumbar spinal stenosis (LSS) is a degenerative disease characterized by intermittent claudication and numbness in the lower extremities. These symptoms are caused compression of nerve tissue lumbar canal. Ligamentum flavum (LF) hypertrophy epidural lipomatosis canal known to contribute canal: however, detailed mechanisms underlying LSS still not fully understood. Here, we show that surgically harvested LFs from patients exhibited significantly increased thickness when transthyretin (TTR),...