Yang Chen

ORCID: 0000-0003-0473-192X
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About
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Research Areas
  • Reproductive Biology and Fertility
  • Obesity, Physical Activity, Diet
  • Nutritional Studies and Diet
  • Birth, Development, and Health
  • Mosquito-borne diseases and control
  • Palliative Care and End-of-Life Issues
  • Ovarian function and disorders
  • Evolution and Genetic Dynamics
  • Diet and metabolism studies
  • Pediatric Pain Management Techniques
  • Nutrition, Health and Food Behavior
  • Childhood Cancer Survivors' Quality of Life
  • Malaria Research and Control
  • COVID-19 epidemiological studies
  • Neuroendocrine regulation and behavior
  • Menstrual Health and Disorders
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Antioxidants, Aging, Portulaca oleracea
  • Virus-based gene therapy research
  • Consumer Attitudes and Food Labeling
  • Frailty in Older Adults
  • vaccines and immunoinformatics approaches
  • Insect symbiosis and bacterial influences
  • Neonatal and Maternal Infections
  • Kruppel-like factors research

Sichuan University
2021-2024

Yangzhou University
2022-2024

Qingdao University
2023

Ministry of Agriculture and Rural Affairs
2022-2023

Jilin Agricultural University
2022-2023

Liaocheng People's Hospital
2023

University of Chinese Academy of Sciences
2023

Seoul National University
2023

Hebei Normal University
2023

West China Medical Center of Sichuan University
2022

Thyroid nodules are one of the most common nodular lesions. The incidence thyroid cancer has increased rapidly in past three decades and is cancers with highest incidence. As a non-invasive imaging modality, ultrasonography can identify benign malignant nodules, it be used for large-scale screening. In this study, inspired by domain knowledge sonographers when diagnosing ultrasound images, local global feature disentangled network (LoGo-Net) proposed to classify nodules. This model imitates...

10.1109/tmi.2022.3140797 article EN IEEE Transactions on Medical Imaging 2022-01-06

The ovary plays a crucial role in the reproductive system of female animals. Ovarian problems such as ovarian insufficiency, premature aging, polycystic syndrome, and cysts may lead to ovulation disorders, abnormal hormone secretion, or luteal dysfunction, thereby increasing risk infertility abortion. Only when function other organs remain healthy work normally can animals be ensured carry out activities regularly, improve pregnancy rate litter size, promote development fetus, then their...

10.3390/antiox13040384 article EN cc-by Antioxidants 2024-03-22

Humoral immunity is important in limiting clinical disease malaria, yet the longitudinal B cell response to infection remains unclear. We performed a 1-year prospective study patients treated for acute P. falciparum malaria first time, or with previous exposure disease. Using an unbiased exploratory approach mass cytometry, followed by targeted flow we found that ~80% of mature cells proliferated expressed CD11c. Only ~40% CD11c+ displayed atypical phenotype, remaining primarily made up...

10.1172/jci.insight.126492 article EN JCI Insight 2019-04-02

Recent studies have shown that histone proteins can act as antimicrobial peptides in host defense against extracellular bacteria, fungi, and Leishmania promastigotes. In this study, we used human recombinant to further study their leishmaniacidal effects the underlying mechanisms. We found histones H2A H2B (but not H1(0)) could directly efficiently kill promastigotes of amazonensis, L. major, braziliensis, mexicana a treatment dose-dependent manner. Scanning electron microscopy revealed...

10.1128/iai.00658-10 article EN Infection and Immunity 2010-12-29

Obesity has become a significant public health problem within China. By observing dietary patterns, an individual's actual habit of nutrients or foods in combination can be identified. We aimed to examine patterns relation the risk obesity (body mass index (BMI) ≥ 25 kg/m2) and weight change (average per five years) Chinese cohort.We analyzed data from 6,677 adults aged 18-65 years China Health Nutrition Survey 1997-2015. Westernized, traditional Chinese, high-starch plant-based were...

10.1371/journal.pone.0279625 article EN cc-by PLoS ONE 2023-01-25

Malaria is the most deadly parasitic infectious disease. Existing drug treatments have limited efficacy in malaria elimination, and complex pathogenesis of disease not fully understood. Detecting novel malaria-associated genes only contributes revealing pathogenesis, but also facilitates discovering new targets for anti-malaria drugs. In this study, we developed a network-based approach to predict genes. We constructed cross-species network integrate human-human, parasite-parasite...

10.1186/1471-2164-16-s7-s9 article EN cc-by BMC Genomics 2015-06-11

Abstract Several epidemiological studies have investigated that Na or K intakes might be associated with the metabolic syndrome (MetS). However, little evidence has evaluated association between Na:K ratio and MetS. In this study, we assessed dietary The cross-sectional study was conducted among adults aged 18 years older in Nanjing, using a multi-stage random sampling method, which resulted sample size of 1993 participants. Dietary were by 3 consecutive days recollection combined condiments...

10.1017/s0007114518001496 article EN British Journal Of Nutrition 2018-08-02

Understanding whether and how melatonin (MT) may impact sheep oocyte development competence is central to our ability predict oocytes will respond artificially regulated estrus. Implanting MT can make enter estrus during the non-breeding season. One study found that blastocyst rate increased under treatment, while another decreased. Therefore, we conducted a meta-analysis of directly indirectly influencing oocytes. A total 433 articles were collected from which 20 34 treatments finally...

10.3389/fvets.2022.903195 article EN cc-by Frontiers in Veterinary Science 2022-05-26

Diet contributes to the increasing incidence of chronic diseases. Thus, fast, accurate, and convenient dietary assessment tools are in demand. We designed an internet-based diet lifestyle questionnaire for Chinese (IDQC). The objective this study was validate its applicability assess habits college students. Six hundred forty-four students from northern China were recruited asked complete IDQC last 4 months (135 food items) 3-day records (3DDRs). Food nutrient intakes recorded validated...

10.1097/md.0000000000002130 article EN cc-by-nc Medicine 2015-12-01

This study aimed to explore the association between health-related quality of life (HRQOL) and diet using three evidence-based dietary indices among older people in rural China.This cross-sectional included 1,258 (mean age 72.32 years; 55.6% female). HRQOL was assessed European Five Dimension Health Scale (EQ-5D), intake a Food Frequency Questionnaire. Three scoring indices, including Alternate Healthy Eating Index, Dietary Approaches Stop Hypertension, Diversity Score (DDS), were calculated...

10.3389/fnut.2023.1259227 article EN cc-by Frontiers in Nutrition 2023-10-19

In this paper, a stochastic SIRS epidemic model with saturating contact rate is constructed. First, for the deterministic system, stability of equilibria discussed by using eigenvalue theory. Second, threshold conditions disease extinction and persistence are established. Our results indicate that large environmental noise intensity can suppress spread disease. Conversely, if small, system has stationary solution which indicates persistent. Eventually, we introduce some computer simulations...

10.3934/mbe.2020316 article EN cc-by Mathematical Biosciences & Engineering 2020-01-01

The mutation types GDF9 S395F and S427R increase the ovulation rate in heterozygotes, while homozygous form leads to infertility. This study presents a meta-analysis of BMP15 SNPs related sheep litter size (LS). results showed that simulation molecular recognition R453H, S395F, was performed effect on dimer. dimer binding ability mutant heterozygotes improved, thereby improving LS. dimers reduced, resulting this will provide important references for animal breeding.

10.1016/j.aoas.2023.12.004 article EN cc-by-nc-nd Annals of Agricultural Sciences 2023-12-01

Abstract This paper investigates a deterministic and stochastic SIQS epidemic model with vertical transmission Beddington–DeAngelis incidence. Firstly, for the corresponding system, global asymptotic stability of disease-free equilibrium endemic is proved through theory. Secondly, threshold conditions which decide extinction or permanence disease are derived. By constructing suitable Lyapunov functions, we investigate oscillation behavior system solution near equilibrium. The results this...

10.1186/s13662-020-02815-6 article EN cc-by Advances in Difference Equations 2020-07-14

Predicting the survival time of patients at end life can provide more accurate treatment and care programs for patients. The purpose this study was to investigate factors impacting 14-day life. This a retrospective study. Patients with advanced cancer admitted Department Palliative Medicine in tertiary hospital China 2021 were included classified into group A (survival ≤ 14 days) or B > days). Patient demographic characteristics, palliative performance scale (PPS) scores, Barthel index...

10.1186/s12904-024-01607-z article EN cc-by-nc-nd BMC Palliative Care 2024-12-02

Litter size is a significant economic trait during animal reproduction. This current study attempted to decipher whether MTHFR promotes the apoptosis of granulosa cells (GCs) and inhibits their proliferation by investigating effects gene using flow cytometry Cell Counting Kit-8 (CCK-8) assay. linked with ovarian follicle development in reproductive performance 104 female New Zealand rabbits. We observed that could regulate mRNA follicular development-related genes (TIMP1, CITED1, FSHR, GHR,...

10.3390/ani14131930 article EN cc-by Animals 2024-06-29
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