A5066357555- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Collaboration in agile enterprises
- Business Strategy and Innovation
- Radiation Therapy and Dosimetry
- Head and Neck Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Innovation and Knowledge Management
- Esophageal Cancer Research and Treatment
- Reproductive biology and impacts on aquatic species
- Advanced Radiotherapy Techniques
- Enzyme Structure and Function
- Lung Cancer Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Effects of Radiation Exposure
- Total Knee Arthroplasty Outcomes
- Erythrocyte Function and Pathophysiology
- MicroRNA in disease regulation
- Immune cells in cancer
- E-commerce and Technology Innovations
- Chemotherapy-related skin toxicity
- Radiation Effects and Dosimetry
- International Business and FDI
Institute of Modern Physics
2022-2025
Chinese Academy of Sciences
2022-2025
Lanzhou University
2024-2025
Jiangxi Academy of Agricultural Sciences
2018-2023
Animal Science Research Institute
2020-2023
Kaohsiung Medical University
2022-2023
MicroPort (China)
2022
Chengdu University of Information Technology
2022
Yangzhou University
2019-2020
Xiangyang Central Hospital
2019
Background Non-small cell lung cancer (NSCLC) is a fatal disease, and radioresistance an important factor leading to treatment failure disease progression. The objective of this research was detect radioresistance-related genes (RRRGs) with prognostic value in NSCLC.
A 10-week feeding trial was conducted to evaluate the effects of dietary lipid sources on growth and immune responses Chinese mitten crab Eriocheir sinensis. Six isonitrogenous isoenergetic diets were formulated with fish oil (FO), linseed (LO), soybean (SO), rapeseed (RO), coconut (CO) beef tallow (BT) as five replicates each. Thirty crabs (2.35 ± 0.14 g) stocked into each tank fed twice daily. Weight gain specific rate FO diet significantly lower than those other (P < 0.05), except for LO...
Experimental diets were formulated containing six levels of linolenic acid (0%, 0.5%, 1.0%, 1.5%, 2.0% and 2.5%) each diet was fed to darkbarbel catfish Pelteobagrus vachelli in triplicate for 84 days. Weight gain, specific growth rate feed efficiency increased with the increasing dietary acid, but not significantly different among 2.5% acid. Red blood cell count haemoglobin higher fish 1.0% than other diets. Lysozyme activity immunoglobulin M content compared Antibody titre 1.0–2.5% acids 0...
This study explored the role of 14-3-3σ in carbon ion-irradiated pancreatic adenocarcinoma (PAAD) cells and xenografts clarified underlying mechanism. The clinical significance patients with PAAD was using publicly available databases. silenced or overexpressed combined ions to measure cell proliferation, cycle, DNA damage repair. Immunoblotting immunofluorescence (IF) assays were used determine mechanisms toward ion radioresistance. We BALB/c mice evaluate biological behavior combination...
Six purified diets were formulated to contain three lipid sources, fish oil (FO), linseed (LO) and soybean (SO), at 6% diet crossing two levels of vitamin E (100 300 mg α-tocopheryl acetate/kg diet) for each source (FO100, FO300, LO100, LO300, SO100, SO300). The juvenile Chinese mitten crab, Eriocheir sinensis, respectively, fed on these with four replicates 6 weeks. crab weight gain (WG) specific growth rate (SGR) significantly affected by dietary sources. No difference was found between...
This study was performed to determine the effects of dietary microencapsulated carvacrol (MC) on growth, resistance A. hydrophila, and intestinal health parameters including bacteria, morphology cytokines, in Pengze crucian carp (Carassius auratus var. Pengze). Fish were divided into four groups. Each group fed a different diet for 56 days (a control or diets supplemented with 200, 400, 600 mg/kg MC). Our results indicate that MC had no effect growth but significantly decreased hydrophila...
: Cancer cells with 'stemness' are generally resistant to chemoradiotherapy. This study aims compare the differences in radiation sensitivity of A549 and CD44
The characterization of protein stability is essential for understanding the functions proteins. Hydroxysteroid dehydrogenase involved in biosynthesis steroid hormones and detoxification xenobiotic carbonyl compounds. However, hydroxysteroid dehydrogenases has not yet been characterized detail. Here, we determined changes Gibbs free energy, enthalpy, entropy, heat capacity unfolding 3α-hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) by varying pH urea concentration through...
In this study, the effect of choline chloride on intestinal microbiota and its association with liver lipid accumulation were tested in zebrafish (Danio rerio) as a model. We performed trial for six weeks dietary high-lipid diets containing different levels (0%, 0.2%, 0.4% 0.6%; labelled C0, C2, C4 C6 treatment, respectively). The samples collected oil red O (ORO) staining at 2nd, 4th 6th week. fatty infiltration formed 2nd week reached maximum proportion C0 treatment week, while lowest was...
Our retrospective study assessed the efficacy and safety of irinotecan plus raltitrexed in esophageal squamous cell cancer (ESCC) patients who were previously treated with multiple systemic therapies. Between January 2016 December 2018, records 38 ESCC underwent chemotherapy after at least one line reviewed. Efficacy assessment was performed every two cycles according to RECIST version 1.1. A total 95 administered, median course 3 (range 2-6). There no treatment-related death. Nine had...
Treating patients with head and neck adenoid cystic carcinoma (HNACC) presents surgical problems in various scenarios. Limited studies explore definitive radiation's impact on patient survival, inadequate data correlating it to postoperative radiotherapy. Using the Surveillance, Epidemiology, End Results (SEER) program, we conducted an objective analysis evaluate of radiation survival HNACC without distant metastases, aiming uncover its nuanced pros cons.
Radiotherapy (RT) is an important means of local treatment solid tumors, and radioresistance the main reason for RT failure especially pancreatic cancer (PC). It urgent to distinguish key genes mechanisms in PC. We acquired data from The Cancer Genome Atlas (TCGA), obtained gene modules associated with by weighted coexpression network analysis (WGCNA), identified differentially expressed (DEGs) between normal tumor samples. Radioresistance-related (RRRGs) were determined intersection WGCNA...
Enzymes are powerful biological catalysts for natural substrates but they have low catalytic efficiency non-natural substrates. Protein engineering can be used to optimize enzymes catalysis and stability. 3α-Hydroxysteroid dehydrogenase/carbonyl reductase (3α-HSD/CR) catalyzes the oxidoreduction reaction of NAD+ with androsterone. Based on structure mechanism, we mutated residues T11, I13, D41, A70, I112 interacted different portions switch cofactor specificity biomimetic nicotinamide...
From the micro-perspective, paper deeply analyzes replication mechanism of routines, important value creation strategy, in order to solve "replication dilemma" new environment.The researches on connotation routines based knowledge, classify it as knowledge template, introduce organization ambidexterity competence match general routine/ exploitation pattern and flexible routine/exploration pattern, then establish path by analysis learning.