- Advanced X-ray Imaging Techniques
- Advanced Electron Microscopy Techniques and Applications
- X-ray Spectroscopy and Fluorescence Analysis
- Crystallography and Radiation Phenomena
- Laser-Plasma Interactions and Diagnostics
- Advanced X-ray and CT Imaging
- Astrophysical Phenomena and Observations
- High-pressure geophysics and materials
- Force Microscopy Techniques and Applications
- Digital Holography and Microscopy
- Tendon Structure and Treatment
- Hydrocarbon exploration and reservoir analysis
- X-ray Diffraction in Crystallography
- Medical Imaging Techniques and Applications
- Drilling and Well Engineering
- Photonic Crystals and Applications
- Seismic Imaging and Inversion Techniques
- Particle Accelerators and Free-Electron Lasers
- Concrete and Cement Materials Research
- Microfluidic and Capillary Electrophoresis Applications
- Catalytic Processes in Materials Science
- Electron and X-Ray Spectroscopy Techniques
- Material Dynamics and Properties
- Enzyme Structure and Function
- Nuclear Physics and Applications
Paul Scherrer Institute
2015-2024
Universidad de Cádiz
2023
American Political Science Association
2023
Rutgers New Jersey Medical School
2022
Rutgers, The State University of New Jersey
2022
Instituto Superior Técnico
2022
Swiss Light Source
2007-2021
ETH Zurich
2008-2018
GEO Partner (Switzerland)
2018
European X-Ray Free-Electron Laser
2018
Using a high-efficiency grating interferometer for hard X rays (10–30 keV) and phase-stepping technique, separate radiographs of the phase absorption profiles bulk samples can be obtained from single set measurements. Tomographic reconstruction yields quantitative three-dimensional maps X-ray refractive index, with spatial resolution down to few microns. The method is mechanically robust, requires little coherence monochromaticity, scaled up large fields view, detector correspondingly...
X-ray ptychography is a scanning variant of coherent diffractive imaging with the ability to image large fields view at high resolution. It further allows non-isolated specimens and can produce quantitative mapping electron density distribution in 3D when combined computed tomography. The method does not require lenses, which makes it dose efficient suitable multi-keV X-rays, where photon counting, pixelated detectors are available. Here we present first highly resolved ptychographic...
Accurate knowledge of translation positions is essential in ptychography to achieve a good image quality and the diffraction limited resolution. We propose method retrieve correct position errors during reconstruction iterations. Sub-pixel accuracy after refinement shown be achievable within several tens Simulation experimental results for both optical X-ray wavelengths are given. The improves retrieved object relaxes requirement while acquiring patterns.
The rising demand for plant-based meat analogues as alternatives to animal products has sparked interest in understanding the complex interplay between their structural and mechanical properties. ability manipulate processing parameters protein blend composition offers fundamental insights into texturization process holds economic sustainable implications food industry. Consequently, correlation properties is crucial achieving consumer satisfaction successful market penetration, providing...
Coherent diffractive imaging provides accurate phase projections that can be tomographically combined to yield detailed quantitative 3D reconstructions with a resolution is not limited by optics.We present robust algorithms for post-processing and alignment of these tomographic projections.A simple method remove undesired constant linear terms on the given.Also, we provide an algorithm automatic has good performance even samples no fiducial markers.Currently applied projections, this proven...
We have employed ptychographic coherent diffractive imaging to completely characterize the focal spot wavefield and wavefront aberrations of a high-resolution X-ray lens.The data from strongly scattering object was acquired using radiation cone emanating coherently illuminated Fresnel zone plate at photon energy 6.2 keV.Reconstructed images were retrieved with spatial resolution 8 nm by combining difference-map phase retrieval algorithm non-linear optimization refinement.By numerically...
X-ray ptychographic computed tomography has recently emerged as a nondestructive characterization tool for samples with representative sizes of several tens micrometers, yet offering resolution currently lying in but not limited to the 100-nm range. Here we evaluate quantitativeness this technique using model sample known structure and density, discuss its sensitivity function resolution. Additionally, show an example application determination mass density individual...
The smaller pixel size and high frame rate of next-generation photon counting detectors opens new opportunities for the application X-ray coherent diffractive imaging (CDI). In this manuscript we demonstrate fast image acquisition ptychography using an Eiger detector. We achieve above 25,000 resolution elements per second, or effective dwell time 40 μs element, when a 500 μm × 290 region integrated electronic circuit with 41 nm resolution. further present scheme sharing information between...
Ptychographic X-ray computed tomography is a coherent diffractive imaging method that offers nanometer-scale resolution with quantitative contrast. It the possibility to study relatively thick samples by using high energy photons and exploiting phase However, limited depth of field forces compromise between sample thickness. Multi-slice techniques have been used account for propagation effects within sample, enabling beyond depth-of-field limit. Here we introduce experimentally demonstrate...
Ptychographic coherent X-ray diffractive imaging (PCDI) has been combined with nano-focus diffraction to study the structure and density distribution of unstained unsliced bacterial cells, using a hard beam 6.2 keV photon energy, focused about 90 nm by Fresnel zone plate lens.While PCDI provides images bacteria quantitative contrast in real space resolution well below size at sample, spatially resolved small angle scattering same (cellular nano-diffraction) structural information highest...
Most studies of structural color in nature concern periodic arrays, which through the interference light create color. The "color" white however relies on multiple scattering within a randomly structured medium, randomizes direction and phase incident light. Opaque materials therefore must be much thicker than structures. It is known that flying insects "white" extremely thin layers. This raises question, whether evolution has optimized wing scale morphology for reflection at minimum...
We demonstrate how the spatial-frequency spectrum of x-ray illumination affects reconstruction signal-to-noise ratio and resolution ptychographic imaging. The a focused probe is enhanced by partially clipping beam with an aperture near its focus. This approach presents simple way enhancing without demanding extra efforts in optics fabrication, we experimentally that it provides improvement image quality resolution.
Over the past decade, ptychography has been proven to be a robust tool for non-destructive high-resolution quantitative electron, X-ray and optical microscopy. It allows reconstruction of specimen's transmissivity, as well recovery illuminating wavefront. Additionally, various algorithms have developed account systematic errors improved convergence. With fast ptychographic microscopes more advanced algorithms, both complexity task data volume increase significantly. PtychoShelves is software...
Despite a century of research, our understanding cement dissolution and precipitation processes at early ages is very limited. This due to the lack methods that can image these with enough spatial resolution, contrast field view. Here, we adapt near-field ptychographic nanotomography in situ visualise hydration commercial Portland record-thick capillary. At 19 h, porous C-S-H gel shell, thickness 500 nm, covers every alite grain enclosing water gap. The rate small grains acceleration period,...
We present an interferometric method to measure the shape of a hard-x-ray wavefront. The interferometer consists phase grating as beam splitter and absorption transmission mask for detector. device can be used wavefront gradients corresponding radii curvature large several dozens meters, with lateral resolution few microns. This corresponds detected distortions approximately 10−12m or λ∕100. was 12.4 keV x rays slope error height profile x-ray mirror. Surface variations periods ranging from...
We report a quantitative measurement of the full transverse coherence function 14.4 keV x-ray radiation produced by an undulator at Swiss Light Source. An grating interferometer consisting beam splitter phase and analyzer amplitude has been used to measure degree as separation out 30 microm. Importantly, technique provides model-free spatially resolved complex is not restricted high resolution detectors small fields view. The spatial characterization wave front important applications in...
A technique has been developed that allows determination of the concentration profiles colloidal solutions or any kind fluid under confinement. Currently, submicrometre-wide channels are sampled with a resolution in 10 nm range. The method comprises regular arrays microfluidic and one-dimensional X-ray phase-retrieval techniques for analysis small-angle diffraction from array structures. Recording data requires low dose on each individual channel since sum signals all is detected. determined...
X-ray microscopy based on Fresnel zone plates is a powerful technique for sub-100 nm resolution imaging of biological and inorganic materials. Here, we report the modeling, fabrication characterization zone-doubled multi-keV regime (4-12 keV). We demonstrate unprecedented spatial by resolving 15 lines spaces in scanning transmission microscopy, focusing diffraction efficiencies 7.5% at 6.2 keV photon energy. These developments represent significant step towards 10 hard energies up to 12 keV.
We present an instrument dedicated to 3D scanning x-ray microscopy, allowing a sample be precisely scanned through beam while the angle of incidence can changed. The position is controlled with respect beam-defining optics by laser interferometry. achieves stability better than 10 nm standard deviation. performance assessed using diffraction microscopy and we demonstrate resolution 18 in 2D imaging lithographic test pattern was defined pinhole 3 μm diameter. In on object copper interconnects...