A5028124007- Natural Antidiabetic Agents Studies
- Phytochemicals and Antioxidant Activities
- Diet, Metabolism, and Disease
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Drug-Induced Hepatotoxicity and Protection
- Antioxidant Activity and Oxidative Stress
- Biochemical effects in animals
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Cannabis and Cannabinoid Research
- Metabolomics and Mass Spectrometry Studies
- Food composition and properties
- Advanced Glycation End Products research
- Biochemical Analysis and Sensing Techniques
- Bee Products Chemical Analysis
- Biochemical Acid Research Studies
- Cassava research and cyanide
- Metabolism, Diabetes, and Cancer
- Free Radicals and Antioxidants
- Fatty Acid Research and Health
- Protein Hydrolysis and Bioactive Peptides
- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Insect and Pesticide Research
University of Johannesburg
2023-2025
Laser Research Institute
2025
University of KwaZulu-Natal
2016-2024
University of the Free State
2019-2024
University of South Africa
2023
Durban University of Technology
2021
Federal Institute of Industrial Research Oshodi
2011-2020
International Center for Chemical and Biological Sciences
2012-2018
University of Karachi
2012-2018
Adamawa State University
2016
High-quality cassava starch (HQCS) produced from high-yielding low-cyanide improved variety, TMS 30572, was mixed with durum wheat semolina (DWS) on a replacement basis to produce flour samples containing 0, 20, 30, 50, 70, and 100% starch. They were analyzed for chemical composition (proximate, amylose, free sugars, starch, wet gluten, cyanide) functional properties (pasting, swelling power, solubility, water absorption, binding, damage, diastatic α-amylase activity, dough mixing,...
Over 90 % of all cases diabetes that have been diagnosed are type 2 (T2D), a disease exacerbated by an increase in sedentary behaviour, bad eating habits, and obesity. This study investigated the antidiabetic properties
Type 2 diabetes has been recognized as the most prominent of all types, contributing to global morbidity and mortality. Availability cost treatment with little or no side effect especially in developing countries remains a huge burden. This led search affordable alternative therapies from natural products medicinal plants. In this study, antidiabetic methanolic extract, dichloromethane (DCM), butanol (BuOH) aqueous fractions Clerodendrum volubile leaves were investigated type diabetic rats...
Oxidative stress is pivotal in the pathology of many diseases. This study investigated antioxidant phytochemistry avocado (Persea americana Mill.) peel. Different solvent extracts (dichloromethane, ethyl acetate, methanol, and water) peel were subjected to total phenol flavonoid quantification, as well vitro radical scavenging ferric reducing evaluation. The methanol extract was gradient column chromatographic fractionation. Fraction 8 (eluted with hexane:chloroform:methanol volume ratio...
This study assessed the cardioprotective effects of <1 kDa peptide fractions from neem seed protein hydrolysates (NSPHs) in cardiac tissues ex vivo. Oxidative injury was induced male Wister rats by incubating with 0.1 mM FeSO4 (pro-oxidant) for 30 minutes. Untreated lacked fractions, while normal control and pro-oxidant. Treatment peptides increased activities/levels catalase, superoxide dismutase, ENTPDase, 5'NTPDase, glutathione, HDL-cholesterol. Conversely, levels/activities...
ABSTRACT Delayed wound healing is among the major peripheral complications of diabetes. Synergistic treatment diabetic wounds (DW) with phytochemicals and non‐invasive techniques has shown promising results. The synergistic effect vanillin photobiomodulation (PBM) on DW healing, their modulatory oxidative stress glucose metabolism was investigated in fibroblast cells (WS1). were treated + PBM. Control consisted WS1 cells, untreated Diabetes induced by repeated growth complete MEM containing...
The chemical properties of the African palm weevil, Rhychophorus phoenicis (F.) (Coleoptera: Curculionidae), larvae were evaluated using standard methodology. chloroform-methanol extract yielded 37.12% on a dry basis. oil was liquid at room temperature with flash point 36.0 °C. Analysis physical constants indicated values 192.25 Wijs and 427.70 mg KOH/g as iodine saponification, respectively. Fatty acid analysis extracted showed presence unsaturated fatty acids low levels. Palmitic stearic...
To investigate the ability of pineapple peels to protect against alcohol-induced oxidative stress in brain tissues using male albino rat models. Response surface methodology (RSM) was used design a series experiments optimize treatment conditions with aim investigating protective effect peel extract on tissues. Oxidative induced by oral administration ethanol (20% w/v) at dosage 5 mL/kg bw. The lasted for 28 days. At end treatment, rats were fasted overnight and sacrificed cervical...
To investigate the ability of methanolic extract pineapple peel to modulate alcohol-induced lipid peroxidation, changes in catalase activities and hepatic biochemical marker levels blood plasma.Oxidative stress was induced by oral administration ethanol (20% w/v) at a dosage 5 mL/kg bw rats. After 28 days treatment, rats were fasted overnight sacrificed cervical dislocation. Blood collected with 2 mL syringe cardiac puncture centrifuged 3 000 rpm for 10 min. The plasma analyzed evaluate...
The progression of secondary complications in type 2 diabetes (T2D) has been linked to oxidative stress caused by hyperglycemia. Therefore, the control hyperglycemia is main target treatment diabetes. present study investigated scavenging and ameliorative potentials different fractions Azadirachta indica (A. indica) ethanol stem bark extract Fe2+-induced injury hepatic tissue as well their ability inhibit enzymes enhancing muscle glucose uptake via some vitro ex vivo experimental models....