A5019292560- Motor Control and Adaptation
- Tactile and Sensory Interactions
- Action Observation and Synchronization
- Visual perception and processing mechanisms
- EEG and Brain-Computer Interfaces
- Multisensory perception and integration
- Stroke Rehabilitation and Recovery
- Obsessive-Compulsive Spectrum Disorders
- Muscle activation and electromyography studies
- Functional Brain Connectivity Studies
- Transcranial Magnetic Stimulation Studies
- Neurological disorders and treatments
- Cerebral Palsy and Movement Disorders
- Virtual Reality Applications and Impacts
- Botulinum Toxin and Related Neurological Disorders
- Electroconvulsive Therapy Studies
- Neural dynamics and brain function
- Neurology and Historical Studies
- Body Image and Dysmorphia Studies
- Advanced Vision and Imaging
- Autism Spectrum Disorder Research
- Neuroscience and Music Perception
- Music Education and Analysis
- Diverse Music Education Insights
- Data Visualization and Analytics
Inserm
2018-2024
Centre National de la Recherche Scientifique
2013-2024
Université Paris Cité
2013-2024
Institut de Psychiatrie et Neurosciences de Paris
2018-2024
Sorbonne Paris Cité
2019-2024
Laboratoire de Neurosciences Cognitives
2020-2022
École Normale Supérieure - PSL
2022
Université Paris Sciences et Lettres
2022
Délégation Paris 5
2018-2020
University College London
2019-2020
Impairments in attentional, working memory and sensorimotor processing have been consistently reported schizophrenia. However, the interaction between cognitive impairments underlying neural mechanisms remains largely uncharted. We hypothesized that altered attentional patients with schizophrenia, probed through saccadic inhibition, would partly explain impaired control be reflected as task-dependent modulation of cortical excitability inhibition. Twenty-five stabilized 17 unaffected...
Background Knowing how impaired manual dexterity and finger proprioception affect upper limb activity capacity is important for delineating targeted post-stroke interventions recovery. Objectives To investigate whether explain variance in capacity, they more than conventional clinical assessments of sensorimotor impairments. Methods Activity hand impairments were assessed using measures N = 42 late subacute/chronic hemiparetic stroke patients. Dexterity was evaluated the Dextrain...
Abstract Perceiving three-dimensional object motion while moving through the world is hard: not only must optic flow be segmented and parallax resolved into shape motion, but also observer needs to taken account in order perceive absolute, rather than observer-relative motion. In simplify last step, it has recently been suggested that if visual background stationary, then foreground computed relative background, directly yields absolute A series of studies with immobile observers simulating...
Abstract Background We developed five tablet-based tasks (applications) to measure multiple components of manual dexterity. Aim: test reliability and validity dexterity measures in healthy participants. Methods Tasks included: (1) Finger recognition assess mental rotation capacity. The subject taps with the finger indicated on a virtual hand three orientations (reaction time, correct trials). (2) Rhythm tapping evaluate timing movements performed with, subsequently without, an auditory cue...
Significance When we actively explore objects by touch, the brain receives two types of signals, tactile sensory inputs and signals about exploratory movement, which must be combined to perceive shape location in space. Whereas these usually come from same body part, have developed a technique separate them, directing one hand movement other. We find that separated synchronized are as if they arose hand. Our results suggest solve difficult problem multidimensional signal combination touch...
Abstract Background Quantitative electroencephalography (EEG) analysis offers the opportunity to study high-level cognitive processes across psychiatric disorders. In particular, EEG microstates translate temporal dynamics of neuronal networks throughout brain. Their alteration may reflect transdiagnostic anomalies in neurophysiological functions that are impaired mood, psychosis, and autism spectrum disorders, such as sensorimotor integration, speech, sleep, sense self. The main questions...
The spatial coding of tactile information is functionally essential for touch-based shape perception and motor control. However, the spatiotemporal dynamics how remapped from somatotopic reference frame in primary somatosensory cortex to spatiotopic remains unclear. This study investigated hand position space or posture influences cortical processing. Twenty-two healthy subjects received electrical stimulation right thumb (D1) little finger (D5) three conditions: palm down on side body...
Neural information processing is subject to noise and this leads variability in neural firing behavior. Schizophrenia has been associated with both more variable motor control impaired cortical inhibition, which crucial for excitatory/inhibitory balance commands.In study, we hypothesized that intracortical inhibition cortex would contribute task-related schizophrenia.We measured of force electromyographic (EMG) activity upper limb hand muscles during a visuomotor grip force-tracking paradigm...
The ability to infer from uncertain information is impaired in schizophrenia and associated with hallucinations false beliefs. accumulation of a key process for generating predictive internal model, which statistically estimates an outcome specific situation. This study examines if updating the model by absence feedback schizophrenia. We explored implicit adaptation probability being instructed perform movement (33%-Go, 50%-Go, or 66%-Go) Go/NoGo task terms reaction times (RTs),...
The extraction of spatial information by touch often involves exploratory movements, with tactile and kinesthetic signals combined to construct a haptic percept. However, the body has many sensory surfaces that can move independently, giving rise source binding problem: when there are multiple originating from bound one another? We studied signal combination applying stationary fingertip while another part (the other hand or foot) visual target moves, using task only be done if combined....
Autism spectrum disorder (ASD) and schizophrenia (SCZ) are neurodevelopmental disorders with partly overlapping clinical phenotypes including sensorimotor impairments. However, direct comparative studies on control across these two lacking. We set out to compare visuomotor upper limb impairment, quantitatively, in ASD SCZ. Patients (N = 24) were compared previously published data from healthy participants patients SCZ 24). All performed a grip force-tracking task single dual-task conditions....
Abstract The shape of objects is typically identified through active touch. accrual spatial information by the hand over time requires continuous integration tactile and movement information. Sensory inputs arising from one single sensory source gives rise to an infinite number possible touched locations in space. This observation raises question determination a common reference frame that might be employed humans resolve ambiguity. Here, we employ paradigm where observers reconstruct...
Locating a tactile stimulus on the body seems effortless and straightforward. However, perceived location of stimulation can differ from its physical [1-3]. Tactile mislocalizations depend timing successive stimulations [2, 4, 5], motion mechanisms [6], or processes that "remap" stimuli skin locations to external space coordinates [7-11]. We report six experiments demonstrating perception localization static part is strongly affected by displacement between two task-irrelevant actions....
Abstract Body representation distortion (BRD) is a core criterion of Anorexia Nervosa (AN), and usually assessed subjectively, focusing on body shape. We aimed to develop new assessment evaluate independently from socially-mediated image, part with low emotional salience (hands). In monocentric open label pilot study, we measured hand representations based explicit (verbal) implicit (tactile) instructions. Participants, eyes closed, had point targeted locations (knuckles nails each finger)...
Stroke often causes long-term motor and somatosensory impairments. Motor planning tactile perception rely on spatial body representations. However, the link between altered representations, deficit coding remains unclear. This study investigates relationship deficits alterations of anatomical (body) representations hand in 20 post-stroke patients with upper limb hemiparesis. Anatomical were assessed from 10 targets (nails knuckles) respectively cued verbally by their name or using...
During the haptic exploration of a planar surface, slight resistances against hand's movement are illusorily perceived as asperities (bumps) in surface. If surface being touched is one's own skin, an actual bump would also produce increased tactile pressure from moving finger onto skin. We investigated how kinaesthetic and signals combine to perceptions during self-touch. Participants performed two successive movements with right hand. A force-control robot applied both movements,...
Perception of space has puzzled scientists since antiquity and is among the foundational questions scientific psychology. Classical “local sign” theories assert that perception spatial extent ultimately derives from efferent signals specifying intensity motor commands. Everyday cases self-touch, such as stroking left forearm with right index fingertip, provide an important platform for studying perception, because tight correlation between tactile extents. Nevertheless, if sensory...