A5061836647- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- HIV Research and Treatment
- Genomics and Phylogenetic Studies
- HIV/AIDS oral health manifestations
- Health, Nursing, Elderly Care
- Machine Learning in Bioinformatics
- CRISPR and Genetic Engineering
- Indigenous Health and Education
- Parasites and Host Interactions
- Maternal and Neonatal Healthcare
- Bacteriophages and microbial interactions
- HIV/AIDS Research and Interventions
- Viral Infections and Immunology Research
Fundação Oswaldo Cruz
2017-2023
Universidade Estadual de Feira de Santana
2017
Chagas disease, caused by the parasite Trypanosoma cruzi (T. cruzi), remains a serious public health problem for which there is no effective treatment in chronic stage. Intense cardiac fibrosis and inflammation are hallmarks of disease cardiomyopathy (CCC). Previously, we identified upregulation circulating miR-21, pro-fibrotic microRNA (miRNA), subjects with CCC. Here, explored potential role miR-21 as therapeutic target model disease. PCR array-based 88 screening was performed heart...
Leishmania braziliensis is the etiological agent of cutaneous leishmaniasis, a disease with high public health importance, affecting 12 million people worldwide. Although its genome sequence was originally published in 2007, two reference annotations still presents at least 80% genes simply classified as hypothetical or putative proteins. Furthermore, it notable absence non-coding RNA (ncRNA) sequences from species databases. These poorly annotated coding and ncRNAs could be important...
Visceral leishmaniasis is an opportunistic disease in HIV-1 infected individuals, unrecognized as a determining factor for AIDS diagnosis. The growing geographical overlap of and Leishmania infections emerging challenge worldwide, co-infection increases morbidity mortality both infections. Here, we determined the prevalence people living with HIV (PWH) previous or ongoing infection by infantum investigated virological immunological factors associated co-infection. We adopted two-stage...
Structural changes in the spleen have been reported several infectious diseases. In visceral leishmaniasis (VL), a severe parasitic disease caused by Leishmania spp., loss of white pulp accompanies clinical presentation. Hamster model reproduces aspects human VL progression. early stages, transcriptomic signature leukocyte recruitment was associated with hyperplasia. Subsequently, impaired chemotaxis T lymphocytes periarteriolar lymphoid sheath occurred. This differential gene expression...
(1) Background: The HIV subtype D is generally associated with a faster decline in CD4+ T cell counts, higher viral load, and progression to AIDS. However, it still poorly characterized Brazil. In this study, we used genomics epidemiological data investigate the transmission dynamics of state Bahia, Northeast (2) Methods: achieve goal, obtained four novel HIV-1 partial pol genome sequences using Sanger method. To understand emergence phylodynamic analysis on dataset comprising 3,704...
(1) Background: The HIV subtype D is generally associated with a faster decline in CD4+ T cell counts, higher viral load, and progression to AIDS. However, it still poorly characterized Brazil. In this study, we used genomics epidemiological data investigate the transmission dynamics of state Bahia, Northeast (2) Methods: To achieve goal, obtained four novel HIV-1 partial pol genome sequences using Sanger method. understand emergence phylodynamic analysis on dataset comprising 3704...
Resumo: Introdução: As comunidades tradicionais são grupos de indivíduos socialmente organizados que partilham comportamentos econômicos, socioambientais e culturais comuns. Entre elas, destacam-se as indígenas no Brasil, vêm sofrendo o impacto da urbanização, do crescimento doenças crônicas epidemias aumento insegurança alimentar. Relato experiência: Este estudo teve como objetivo descrever experiências equipe saúde, quanto ao uso uma ferramenta gestão dados na assistência, em comunidade...
ABSTRACT Background Visceral leishmaniasis is an opportunistic disease in HIV-1 infected individuals, although not yet recognized as a determining factor for AIDS diagnosis. The growing geographical overlap of and Leishmania infections emerging challenge worldwide, co-infection increases morbidity mortality both. Here, we determined the prevalence people living with HIV (PWH) previous or ongoing infection by infantum Bahia, Brazil investigated virological immunological factors associated...