A5100711019- Optical measurement and interference techniques
- Optical Coherence Tomography Applications
- Image Processing Techniques and Applications
- Advanced Measurement and Detection Methods
- Ultrasonics and Acoustic Wave Propagation
- Surface Roughness and Optical Measurements
- Photoacoustic and Ultrasonic Imaging
- Bone Tissue Engineering Materials
- Advanced Measurement and Metrology Techniques
- Optical Systems and Laser Technology
- Coronary Interventions and Diagnostics
- Thermography and Photoacoustic Techniques
- Cerebrovascular and Carotid Artery Diseases
- Mechanical Behavior of Composites
- Advanced Surface Polishing Techniques
- Structural Health Monitoring Techniques
- Material Properties and Processing
- Additive Manufacturing and 3D Printing Technologies
- Cellular Mechanics and Interactions
- Tissue Engineering and Regenerative Medicine
- Ultrasound Imaging and Elastography
- Industrial Vision Systems and Defect Detection
- Peripheral Artery Disease Management
- Orthopaedic implants and arthroplasty
- Cardiovascular Health and Disease Prevention
Tianjin University
2011-2024
National Clinical Research Center for Digestive Diseases
2024
Capital Medical University
2024
Beijing Friendship Hospital
2024
Weatherford College
2024
Gannan Normal University
2024
Tzu Chi University
2014-2022
Sun Yat-sen University
2014
National Taipei University
2013
Amgen (United States)
2011
Agonists of GPR40 (FFA1) have been proposed as a means to treat type 2 diabetes. Through lead optimization high throughput screening hit, we identified novel agonist called AMG 837. The objective these studies was understand the preclinical pharmacological properties activity 837 on characterized through GTPγS binding, inositol phosphate accumulation and Ca2+ flux assays. Activity insulin release assessed isolated primary mouse islets. To determine anti-diabetic in vivo, tested using glucose...
The aim of this study was to investigate the anti-hyperglycemic activity and mechanism formononetin in alloxan-induced type 1 diabetic mice by determining its effect on some diabetes-related indices as described below. Body weight, fasting blood glucose, hepatic glycogen, serum insulin, glucagon were determined electronic scales, glucometer, ELISA kits. Fas, Caspase-3, pancreatic duodenal homeobox-1 , insulin receptor substrate 2, glucokinase glucose transporter mRNA proteins levels pancreas...
Abstract Depth-resolved, non-contact, full-field three-dimensional (3D) deformation measurement is essential for the application of hydrogels in biomimicry, soft robotics, and optical components. However, current methods are constrained to surface measurements encounter difficulties underwater settings. Leveraging 3D depth-resolved imaging capabilities coherence tomography (OCT), we propose an OCT-based method measuring water. This integrates electrically driven devices with a Limited-memory...
The three-dimensional (3D) mechanical property characterization of biological tissues is essential for physiological and pathological studies. A digital volume correlation (DVC) virtual fields method (VFM) based 3D optical coherence elastography (OCE) developed to quantitatively measure the full-field displacements, strains elastic parameters layered biomaterials assuming isotropy homogeneity each layer. integrated noise-insensitive DVC can obtain strain tensor with an accuracy 10%....
Recent epidemiological research suggests a possible negative correlation between Helicobacter pylori infection and inflammatory bowel disease (IBD). However, conflicting studies have provided unclear evidence regarding these causal relationships. Therefore, recommending specific prevention treatment strategies for H. IBD is challenging. We used various antibodies (anti-H. IgG, VacA, GroEl) related to as indicators. acquired relevant genetic variants from public databases within the...
An optical and semidestructive method to determine surface residual stress, which combines digital image correlation (DIC) with sharp indentation testing, is proposed. Based on the expanding cavity model, when a semi-infinite body subjected uniform equi-biaxial or applied stresses, displacement around satisfies radial profiles. Therefore, relation between stresses of can be determined. The described was tested using experiments for different stress states in aluminum. These were generated...
Bioassay-guided fractionation of the ethanolic extract leaves Flickingeria flimbriata led to isolation two new degraded diterpenoids 1 and 2, a ent-pimarane type diterpenoid 3, four known steroids 4–7. The structures 1–3 were elucidated by spectroscopic analysis, their absolute configurations determined chemical methods, TDDFT quantum calculations ECD spectra, CD exiton chirality method. Compounds named flickinflimilins A B, possess rare 15,16-dinor-ent-pimarane skeleton. 1–7 screened for...
Thoracic breathing (TB), abdominal (AB), and mixing are common respiratory functions. Individuals usually breathe thoracically, whereas the pattern of AB is vague. Despite statistical representation physiological benefits AB, coping with a time-variant environment still remains challenging. Therefore, based on ensemble empirical mode decomposition (EEMD), this study compares identification types using R value, power proportion, modified significant test (MST). Respiratory maneuver 26...
Many mechanical phenomena of interest for web-like materials, such as molded pulp, take place at the micro-scale. A SEM (scanning electron microscope) with SHIMADZU electrohydraulic servo experimental system was employed to study micro-scale behavior pulp materials. Uniaxial tension tests specimens were carried out, resulting in stress-strain curves. Experimental results indicated that material is not only elasticplastic, but also emplastic. The surface morphology evolution tensile specimen...
Optical coherence elastography (OCE) based on digital volume correlation (DVC) has the advantages of full 3D displacements and strain tensor quantification. However, measurement results are often unreliable due to poor quality optical tomography (OCT) speckle patterns. This paper proposes an image evaluation index OCT-DVC (CMGG, combined mean attenuation intensity, breadth dispersion gray level distribution), which comprehensively considers OCT signals’ distribution images. Virtual...
Abstract Post-operative bile leakage (POBL) is a serious complication following hepatobiliary surgery, with potentially life-threatening consequences if left untreated. This article presents successful case of POBL management without surgical intervention. A 31-year-old male, diagnosed before hospitalisation, underwent percutaneous biliary drainage (PTBD) to address bilomas. Follow-up after 3 months indicated biloma atrophy and healing but revealed duct stenosis. The patient received larger...