A5100407086- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Stroke Rehabilitation and Recovery
- Cerebrovascular and Carotid Artery Diseases
- Clinical practice guidelines implementation
- Sepsis Diagnosis and Treatment
- Hospital Admissions and Outcomes
- Patient Satisfaction in Healthcare
- Heart Failure Treatment and Management
- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Healthcare Operations and Scheduling Optimization
- Healthcare Systems and Public Health
- Nutrition, Genetics, and Disease
- Obsessive-Compulsive Spectrum Disorders
- Physical Education and Training Studies
- Gynecological conditions and treatments
- Retinal and Optic Conditions
- Frailty in Older Adults
- Economic and Financial Impacts of Cancer
- Disaster Response and Management
- Advanced Breast Cancer Therapies
- Inhalation and Respiratory Drug Delivery
Simcere Pharmaceutical (China)
2024
Harbin Medical University
2013-2024
Shanxi Medical University
2024
First Hospital of Shanxi Medical University
2024
Beijing Sport University
2023
Inner Mongolia Medical University
2023
Jilin University
2020-2022
Capital Medical University
2021-2022
Third Affiliated Hospital of Harbin Medical University
2019-2022
First Hospital of Jilin University
2020-2022
Background and Purpose: A recent randomized controlled trial DIRECT-MT (Direct Intra-Arterial Thrombectomy to Revascularize AIS Patients With Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals) compared the safety efficacy of mechanical thrombectomy (MT) versus combined intravenous thrombolysis (IVT) MT for acute large vessel occlusion. The current study utilized a prospective, nationwide registry validate results real-world practice setting. Methods: Subjects were selected...
Background Residual venous defects after atrial septal defect (ASD) repair may remain asymptomatic for years and can be misinterpreted as partial anomalous pulmonary return. Accurate intraoperative imaging is essential to confirm the anatomy guide repair, particularly in minimally invasive surgery. Case presentation A 28-year-old woman with no cardiopulmonary symptoms was referred an abnormal electrocardiographic findings during a routine physical examination. She had undergone ASD at age 3....
Restorative sleep is an important component of quality life. Disturbances in after burn injury were reported but all based on uncontrolled or nonstandardized data. The occurrence and the effect long-term problems young adult survivors have not been well defined. This 5-year (2003-2008) prospective multicenter longitudinal study included adults with injuries ages 19 to 30 years who completed Young Adult Burn Outcome Questionnaire (YABOQ) up 36 months injury. items measured 15 patient-reported...
Abstract Background M 3 muscarinic acetylcholine receptor (M -mAChR) is stably expressed in the myocardium, but its pathophysiological role remains largely undefined. This study aimed to investigate of -mAChR cardiac hypertrophy induced by angiotensin II (Ang II) and elucidate underlying mechanisms. Methods Cardiac-specific overexpression transgenic (TG) mice rat H9c2 cardiomyoblasts with ectopic expression were established. Models transverse aortic constriction (TAC) or Ang infusion vivo ,...
A wide variation exists in the practice patterns of acute myocardial infarction (AMI) care worldwide, leading to differences clinical outcomes. This study aims evaluate quality process and its impact on in-hospital outcomes among AMI patients Pakistan, as no such has been conducted Pakistan thus far based upon recommended guidelines. We investigated a sample 2663 across 11 territory hospitals Punjab province Lahore, Faisalabad, Multan, Rawalpindi, Islamabad from January 1, 2016 December 31,...
The role of stroke etiology subtype in patients with acute large vessel occlusion on the occurrence hemorrhagic transformation (HT) after endovascular treatment is poorly studied, and which factors mediate their relationship remains largely unknown. We utilized nationwide registry data to explore association (cardioembolism versus artery atherosclerosis) HT identify possible mediators.A total 1015 subjects were selected from ANGEL-ACT (Endovascular Treatment Key Technique Emergency Work Flow...
Abstract Background Clinical trials have demonstrated the efficacy of edaravone dexborneol in treatment acute ischemic stroke. This study aims to determine cost-effectiveness compared with human urinary kallidinogenase from China’s healthcare system perspective. Methods A combination decision tree and Markov model was constructed evaluate versus stroke over a lifetime horizon. Efficacy data were derived pivotal clinical (TASTE trial RESK trial, respectively) adjusted using matching-adjusted...
Stump syndrome refers to cerebral ischaemic symptoms caused by an embolus from a previously occluded ipsilateral artery that occludes down-stream artery. It can be divided into two types: carotid stump and vertebral (VASS). At present, there is limited clinical experience with VASS. We aimed propose more precise diagnostic standard for VASS, share our handling this condition.We retrospectively collected data of patients who were treated endovascular thrombectomy in the stroke centre First...
Background and aim Benchmarking is a management approach for implementing best medical practices at the lowest cost. The objectives of this study were to set achievable performance benchmarks individual quality indicators determine predicted achievement related better adherence, select optimal improving acute ischemic stroke care. Methods We analyzed data on 500,331 patients diagnosed with who treated 518 hospitals in China from January 2011 May 2017. primary outcome was independence...
Prognosis and Health Management (PHM), critical for ensuring task completion by complex systems preventing unexpected failures, is widely adopted in aerospace, manufacturing, maritime, rail, energy, etc. However, PHM's development constrained bottlenecks like generalization, interpretation verification abilities. Presently, generative artificial intelligence (AI), represented Large Model, heralds a technological revolution with the potential to fundamentally reshape traditional fields human...
There are differences in the quality of care among breast cancer patients. Narrowing could be achieved by increasing utilization rate indicators. Here we explored key indicators that can improve and factors may affect use these indicators.A total 3669 patients were included our retrospective study. We calculated patient quality-of-care composite score based on average method. Patients divided into high- low-quality groups according to mean score. obtained with large difference between two...
Background The admission time of patients with ST-segment elevation myocardial infarction (STEMI) may affect the quality care they receive. This study aimed to explore pattern and magnitude variation in for STEMI both process outcome domains. Methods We performed a retrospective based on data from China. estimated adjusted ORs six indicators one indicator by fitting multilevel multivariable regression models across 42 4hour periods per week. Results cohort comprised 98 628 STEMI. Care varied...
Background : Intravenous thrombolysis (IVT) therapy is currently one of the best medical treatments available for patients with acute ischemic stroke. Studies have shown that blood pressure (BP) changes in treated IVT are significantly correlated prognosis. Objective Our study aimed to determine relationship between BP during recombinant tissue plasminogen activator (rt-PA) infusion and 3-month prognosis evaluated using modified Rankin Scale (mRS) factors influencing rt-PA infusion. Methods...
Rationale/Aim: Many patients undergoing successful recanalization after endovascular thrombectomy (EVT) do not have a good outcome; additional neuroprotection might benefit this group. Remote ischemic conditioning (RIC) stimulates endogenous protective mechanisms and may neuroprotective in acute brain ischemia. The safety efficacy of RIC combined with (SERIC-EVT) trial is investigating the for stroke (AIS) who underwent EVT due to large vessel occlusion anterior circulation. Methods:...
Abstract We aim to determine the correlation between parental rearing, personality traits, and obsessive–compulsive disorder (OCD) in different quantiles. In particular, we created an intermediary effect model which rearing affects OCD through traits. All predictors were measured at time of survey, comprising (paternal maternal rearing), demographics (grade gender), traits (neuroticism, extroversion, psychoticism). These results suggest that (a) paternal emotional warmth was negatively...
Background: Adherence to evidence-based hospital stroke care is variable and may change over time. It important determine which process measures are associated with variation in outcome. In a large dataset, we analyzed the association between outcome fluctuations of indicators time, identified quality (QIs) that should be prioritized for improving care. Methods: We data from 123,259 patients diagnosed acute ischemic (AIS) who were treated at 109 tertiary hospitals China January 2011 May...
Abstract Background Pertuzumab and trastuzumab (P H; F. Hoffmann-La Roche Ltd, Basel, CH) bind to distinct HER2 subdomains have complementary modes of anticancer activity in HER2-positive breast cancer (BC). A global Phase II study (NeoSphere) reported that neoadjuvant treatment with P+H+docetaxel (D) significantly increased pathologic complete response (bpCR) vs H+D patients (pts) early/locally advanced/inflammatory BC (Gianni et al. Lancet Oncol 2012). PEONY (NCT02586025), a randomized,...
Objective：To study the risk factors of cervical insufficiency (CI). Design：Retrospective controlled study. Setting：First Hospital Shanxi Medical University. Population：209 CI patients with a singleton pregnancy (CI group) and 348 randomly selected (control group). Methods main outcome measures：All were required to have records whole pregnancy. The general conditions complications two groups collected. A model logistic regression ROC curves used. Results：Patients history multiple pregnancies...
The quality of care for patients may be partly determined by the time they are admitted to hospital. This study was conducted explore effect admission and describe pattern magnitude weekly variation in patient care.