A5102786195- Ion channel regulation and function
- Adipose Tissue and Metabolism
- Blood Pressure and Hypertension Studies
- Mitochondrial Function and Pathology
- Cardiac electrophysiology and arrhythmias
- Exercise and Physiological Responses
- Signaling Pathways in Disease
- Global Maternal and Child Health
- Parallel Computing and Optimization Techniques
- Trypanosoma species research and implications
- Corporate Identity and Reputation
- Cardiovascular Function and Risk Factors
- Thermoregulation and physiological responses
- SARS-CoV-2 and COVID-19 Research
- Calpain Protease Function and Regulation
- ATP Synthase and ATPases Research
- Viral Infections and Vectors
- Health and Well-being Studies
- Global Health and Epidemiology
- RNA and protein synthesis mechanisms
- Public Relations and Crisis Communication
- Advanced Data Storage Technologies
- Renal function and acid-base balance
- Neurobiology and Insect Physiology Research
- Mosquito-borne diseases and control
Shri Jagannath Sanskrit University
2024
The Ohio State University
2005-2021
Maharaja Krishna Chandra Gajapati Medical College and Hospital
2017-2021
Discovery Institute
2015-2018
Sanford Burnham Prebys Medical Discovery Institute
2015-2018
All India Institute of Hygiene and Public Health
2015-2016
Gwangju Institute of Science and Technology
2008-2010
The major objective of this study was to understand the molecular basis how sarcolipin uncoupling SERCA regulates muscle oxidative metabolism. Using genetically engineered (SLN) mouse models and primary cells, we demonstrate that SLN plays a crucial role in mitochondrial biogenesis metabolism muscle. Loss severely compromised capacity without affecting fiber-type composition. Mice overexpressing fast-twitch glycolytic reprogrammed phenotype, increasing fat utilization protecting against...
Hypertension is one of the major public health problem affecting whole world so its accurate measurement utmost importance for early diagnosis and management. Concerns related to potential ill effects mercury on environment, has led widespread use non-mercury sphygmomanometers.A study was conducted compare accuracy readings aneroid digital sphygmomanometers in reference determine hypertensive classification agreement between devices.The an OPD a centre rural community West Bengal which field...
OPINION article Front. Physiol., 27 September 2018Sec. Integrative Physiology Volume 9 - 2018 | https://doi.org/10.3389/fphys.2018.01217
Calumenin is a multiple EF-hand Ca(2+)-binding protein localized in the sarcoplasmic reticulum (SR) with C-terminal SR retention signal HDEF. Recently, we showed evidence that calumenin interacts SERCA2 rat cardiac (Sahoo, S. K., and Kim, D. H. (2008) Mol. Cells 26, 265-269). The present study was undertaken to further characterize association of mouse heart by various gene manipulation approaches. Immunocytochemical analysis were partially co-localized HL-1 cells. Knockdown (KD) conducted...
Calumenin, a multiple EF-hand Ca2+ binding protein is located in the SR of mammalian heart, but functional role heart unknown. In present study, an adenovirus gene transfer system was employed for neonatal rat to examine effects calumenin overexpression (Calu-OE) on transients. Calu-OE (8 folds) did not alter expression levels DHPR, RyR2, NCX, SERCA2, CSQ and PLN. However, affected several parameters Among them, prolongation time 50% baseline (T50) most outstanding change electrically-evoked...
Abstract This was a population based cross-sectional study carried out to estimate and compare the seroprevalence, hidden prevalence determine demographic risk factors associated with SARS-CoV-2 infection among adults in three largest cities of Odisha, India, ascertain association progression epidemic. The survey August 2020 state India. Blood samples were collected from residents using random sampling methods tested for anti- SARS CoV-2 antibodies an automated CLIA platform. A total 4146...
A small peptide regulates muscle thermogenesis through interaction with the sarcoplasmic reticulum calcium ATPase.
A very challenging issue for optimizing compilers is the phase ordering problem: In what order should a collection of compiler optimizations be performed? We address this problem in context sequence tensor contractions. The pertinent loop transformations are permutation, tiling, and fusion; addition, placement disk I/O statements crucially affects performance. space possible combinations exponentially large. develop novel pruning strategies whereby search larger replaced by large number...
Background: Vector borne diseases (VBDs) form a major part of the communicable in India. Ignorance and impoverished conditions people contribute creating source spread vector hinder disease control strategy. Slums are more vulnerable to because poor environmental condition, standard living, poverty ignorance people. This study is small endeavour highlight awareness residents slum area Chetla, Kolkata, West Bengal, India regarding diseases. Objectives were assess population different find out...
Background: Noncommunicable diseases (NCDs) are the major contributors of morbidity and mortality in elderly people. Among them, hypertension is one most important treatable causes population. Furthermore, high blood pressure a modifiable risk factor cardiovascular disease. Objective: To find out magnitude its association with sociodemographic behavioral characteristics. Materials Methods: A cross-sectional study was conducted on 200 people (age ≥ 60 years) an urban slum, Chetla, under...
Objectives: Japanese encephalitis (JE) is a vector-borne viral disease that primarily infects swines, equids, and humans. Outbreaks of JE-acute syndrome were reported from September to November 2012 9th 2nd December 2016 in Malkangiri district, Odisha. Due the paucity studies on JE transmission, causation, prevention tribal areas, present study was undertaken assess vaccination status children between 12 36 months Mayurbhanj district determine association sociodemographic characteristics...
Objective: Agriculture is one of the most hazardous occupations in developing and industrialized countries. Most agricultural workers countries have poor housing conditions an inadequate diet are exposed to both general occupational diseases. The study was undertaken find out prevalence morbidity its associated risk factors among a rural Block West Bengal. Methods: conducted agriculture Habra Block-I state Multistage random sampling method followed select total 302 individuals who were...
Objectives: The pandemic of the recently emerged 2019- novel coronavirus infection was a challenge to public health. current gold standard for molecular diagnosis severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is reverse transcription polymerase chain reaction (RT-PCR) qualitative and quantitative detection viral nucleic acids. However, superior combination gene targets SARS-CoV-2 underexplored. To find out possible target genes maximizing RT-PCR accuracy in detection. Methods:...
This paper develops an algorithm to accurately characterize the number of cache misses for a class compute-intensive calculations encountered in accurate quantum chemistry models electronic structure. The proposed approach can handle imperfectly nested loop structures, symbolic bounds, and non-constant dependences constrained array references. It is context tensor contraction computations, extends previous work on "stack distances" by Almasi et al. (2002) Cascaval (2003). We illustrate...
Background: Non-communicable diseases (NCD) are the leading cause of adult mortality and morbidity worldwide now days. The NCD like hypertension is emerging as a major health problem in India with increasing prevalence significantly both urban rural population. objectives study were to find out its association socio-demographic factors among subjects, if any. Methods: This cross-sectional was conducted from May, 2013 April, 2014 communities Singur block 651 individuals, aged 20 years or...