A5062308092- Orthopaedic implants and arthroplasty
- Hip disorders and treatments
- Total Knee Arthroplasty Outcomes
- Lipid Membrane Structure and Behavior
- Titanium Alloys Microstructure and Properties
- Orthopedic Infections and Treatments
- Force Microscopy Techniques and Applications
- Bone Tissue Engineering Materials
- Additive Manufacturing Materials and Processes
- Lower Extremity Biomechanics and Pathologies
- Bone fractures and treatments
- Osteoarthritis Treatment and Mechanisms
- Shoulder Injury and Treatment
- Muscle activation and electromyography studies
- Additive Manufacturing and 3D Printing Technologies
- Cellular Mechanics and Interactions
- Hip and Femur Fractures
- Musculoskeletal pain and rehabilitation
- Spectroscopy and Quantum Chemical Studies
- Shoulder and Clavicle Injuries
- Bone and Joint Diseases
- Surfactants and Colloidal Systems
- Orthopedic Surgery and Rehabilitation
- Prosthetics and Rehabilitation Robotics
- Polymer Surface Interaction Studies
Czech Technical University in Prague
2015-2024
Tun Hussein Onn University of Malaysia
2024
Biomechanics Institute of Valencia
2019-2021
Edward Via College of Osteopathic Medicine
2020
Faculty (United Kingdom)
2019
University of California, Los Angeles
2017
Technical University of Košice
2005-2007
University of Chemistry and Technology, Prague
2003
University of Ljubljana
2001-2002
Ljubljana University Medical Centre
2001
Additive manufacture (AM) appears to be the most suitable technology produce sophisticated, high quality, lightweight parts from Ti6Al4V alloy. However, fatigue life of AM is concern. In our study, we focused on a comparison two techniques additive manufacture—selective laser melting (SLM) and electron beam (EBM)—in terms mechanical properties during both static dynamic loading. All samples were untreated focus influence surface condition inherent SLM EBM. The EBM studied in as-built state,...
To assess the reliability and minimal clinically important differences (MCID) for FVC% predicted in Scleroderma Lung Study I II.
By using a mathematical model of the adult human hip in static one-legged stance position body, forces acting on hip, peak stress joint and other relevant radiographic biomechanical parameters were assessed. The aims to examine if dysplastic hips is higher than normal find out which contribute significantly stress. average normalized (7.1 kPa/N) was markedly (to approximately 100%) (3.5 kPa/N). characteristic that contributed included smaller lateral coverage femoral head, larger interhip...
Obesity has reached epidemic proportions in the United States. Recently, obesity, especially morbid been linked to increased rates of dislocation after THA. The reasons are unclear. Soft tissue engagement caused by thigh girth proposed as a possible mechanism for decreased joint stability.We asked (1) whether soft impingement could decrease THA stability, and if so, at what level BMI this effect might become evident; (2) how construct factors (eg, head size, neck offset, cup abduction)...
Euler angle representation in biomechanical analysis allows straightforward description of joints rotations. However, application angles could be limited due to singularity called gimbal lock. Quaternions offer an alternative way describe rotations but they have been mostly avoided biomechanics as are complex and not inherently intuitive, specifically dynamic models actuated by muscles. This study introduces a mathematical framework for describing muscle actions quaternion-based...
Background: The diagnosis of joint replacement infection is a difficult clinical challenge that often occurs when the implant cannot be salvaged. We hypothesize pH value synovial fluid could an important indicator inflammatory status joint. However, in literature, there lack data on changes hip and knee replacements their relation to failure. In this study, we aimed measure levels patients with replacements. also investigated potential measurement as diagnostic tool for infection. recorded...
The biomechanical role of the horseshoe geometry acetabular cartilage is described using a three-dimensional mathematical model. It shown that fossa contributes to more uniform articular contact stress distribution and consequent decrease in peak stress. Based on results it suggested characteristic shape human acetabulum optimizes hip joint.
Small hydrophobic gold nanoparticles with diameter lower than the membrane thickness can form clusters or uniformly distribute within core of bilayer. The coexistence two stable phases (clustered and dispersed) indicates energy barrier between nanoparticles. We calculated distance dependence membrane-mediated interaction adjacent In our model we consider deformation modes: monolayer bending hydroxycarbon chain stretching. Existence an clustered separated state was predicted. Variation...
The formation of nanostructures on titanium implant surfaces is a promising strategy to modulate cell adhesion and differentiation, which are crucial for future application in bone regeneration. aim this study was investigate how the nanotube diameter and/or nanomechanical properties alter human osteoblast like (Saos-2) adhesion, growth osteogenic differentiation vitro. Nanotubes, with diameters ranging from 24 66 nm, were fabricated commercially pure (cpTi) surface using anodic oxidation...
This paper explores the influence of sample thickness and build orientation on microstructure mechanical properties electron beam melting (EBM) additive manufactured Ti-6Al-4V titanium alloy compared to previously published work SLM-processed material. In particular, various (tensile yield strength, ultimate tensile strength) were investigated with attempts correlate microstructural features, including lamellae thickness, porosity size prior-beta grains. However, it is shown that surface...
The mathematical models and the corresponding computer program for determination of hip joint contact force, stress distribution, size weight bearing area from a standard anteroposterior radiograph are described. described method can be applied in clinical practice to predict an optimal distribution after different operative interventions analyze short long term outcome treatment various pathological conditions hip. A group dysplastic hips normal were examined, with respect peak normalized...
In this study we present experimental and theoretical results which concern the deviations from circularity of pivotal plane in inverse hexagonal phases (H(II)) phospholipid self-assemblies. Due to packing constraints, cross-section polar/apolar interface deviates a circle, studied minute detail by analysing small-angle X-ray diffraction data dioleoyl-phosphatidylethanolamine (DOPE) stearoyl-oleoyl-phosphatidylethanolamine (SOPE), respectively. On structural basis, Monte Carlo (MC) simulated...
Background: Slipping of the capital femoral epiphysis is an important orthopaedic problem early adolescence. Many hypotheses about its etiology have been examined, yet underlying mechanisms not fully elucidated. We examined elevated shear stress in epiphyseal growth plate and contact hip exerted on head as risk factors for slipping epiphysis. Methods: Two groups hips were compared: a group 100 contralateral to slipped ones 70 age- gender-matched healthy hips. The characteristics individual...
Hip contact stress is considered to be an important biomechanical factor related development of coxarthrosis. The effect the lateral coverage acetabulum on hip has been demonstrated in several studies dysplasia, whereas anterior anteversion remains unclear. Therefore, joint during normal level walking and staircase walking, dysplastic hips, for small large acetabular angle was computed. For angle, slightly increased (less than 15%) when compared with walking. In hips anteversion, downstairs...
The role of phospholipid asymmetry in the transition from lamellar (Lα) to inverted hexagonal (HII) phase upon temperature increase was considered. equilibrium configuration system determined by minimum free energy including contribution isotropic and deviatoric bending interstitial monolayers. shape local interactions a single lipid molecule were taken into account. minimization with respect layers performed numerical solution Euler−Lagrange differential equations Monte Carlo simulated...
Fundamental understanding of vesicle adhesion in the size range ≤ 200 nm is major importance when addressing biologically relevant processes involving presence small vesicles like exosomes or endosomes. Using quartz crystal microbalance with dissipation monitoring, we investigate correlation between deformation and eventual membrane rupture on surfaces different levels, as well their respective thermotropic phase transitions. In particular, transitions solid-supported membranes Au resemble...
Additive manufacturing technologies allow producing a regular three-dimensional mesh of interconnected struts that form an open-cell porous structure. Regular structures have been used in the orthopedic industry due to outstanding bone anchoring. The aim study was determine how postprocessing influences mechanical properties made titanium alloy CL 41TI ELI. effect hot isostatic pressing (HIP) as method increasing microstructural integrity investigated here. influence surface etching (SE)...