A5017905393- Myasthenia Gravis and Thymoma
- Amyotrophic Lateral Sclerosis Research
- Parkinson's Disease Mechanisms and Treatments
- Parkinson's Disease and Spinal Disorders
- Neurogenetic and Muscular Disorders Research
- Thyroid and Parathyroid Surgery
- biodegradable polymer synthesis and properties
- Long-Term Effects of COVID-19
- Restless Legs Syndrome Research
- Neuroscience of respiration and sleep
- Psoriasis: Treatment and Pathogenesis
- Advanced Topics in Algebra
- COVID-19 and healthcare impacts
- Autoimmune Bullous Skin Diseases
- HER2/EGFR in Cancer Research
- Pharmacological Effects and Toxicity Studies
- Pericarditis and Cardiac Tamponade
- Peripheral Neuropathies and Disorders
- Cardiac tumors and thrombi
- Healthcare Decision-Making and Restraints
- Alzheimer's disease research and treatments
Columbia University Irving Medical Center
2023-2025
Columbia University
2021-2025
The Neurological Institute
2021-2024
Cleveland Clinic
2024
Colorado School of Public Health
2024
University of Alabama at Birmingham
2019-2021
During the COVID-19 pandemic, patients with neuromuscular disorders, especially autoimmune myasthenia gravis, might be at greater risk of worse outcomes than otherwise healthy people because an immunocompromised state related to immunotherapy and possible respiratory bulbar muscular weakness. However, cessation in neuroinflammatory disorders has severe risks as well.1Korsukewitz C Reddel SW Bar-Or A Wiendl H Neurological era COVID-19—looking for consensus literature.Nat Rev Neurol. 2020; 16:...
Abstract Objective We examined whether riluzole treatment modifies the associations between dietary glycemic index (GI) and load (GL) disease progression in amyotrophic lateral sclerosis (ALS). Methods Sporadic ALS patients Multicenter Cohort Study of Oxidative Stress who completed a baseline food frequency questionnaire were included ( n = 304). Interactions GI/GL on functional decline tracheostomy‐free survival using linear regression Cox proportional hazard models adjusted for covariates....
Background/objective Weight loss is a predictor of shorter survival in amyotrophic lateral sclerosis (ALS). We performed serial measures body composition using Dual-energy X-ray Absorptiometry (DEXA) ALS patients to explore its utility as biomarker disease progression. Methods DEXA data were obtained from participants with (enrollment, at 6- and 12- months follow ups) Parkinson’s (enrollment 4-month up) comparator group. Body mass index, total lean appendicular fat percentage enrollment...
High-caloric diets may slow the progression of amyotrophic lateral sclerosis; however, key macronutrients have not been identified. We examined whether dietary are associated with rate and length survival among prospective cohort study participants.
We studied the progression of myasthenia gravis (MG) disease burden and medication adjustment among MG Patient Registry participants.Participants diagnosed with (age ≥18 years), registered between July 1, 2013 31, 2018 completing both 6- 12-month follow-up surveys, were included in this investigation. Participants grouped into high-burden (Myasthenia Gravis Activity Daily Living scale [MG-ADL] score ≥6) low-burden (MG-ADL <6) groups based on MG-ADL scores at enrollment. Demographics history...
There are currently no imaging or blood diagnostic biomarkers that can differentiate amyotrophic lateral sclerosis (ALS) from primary (PLS) patients early in their disease courses. Our objective is to examine whether with PLS be differentiated ALS reliably by using plasma lipidome profile and supervised machine learning.40 28 derived the Multicenter Cohort study of Oxidative Stress (COSMOS) healthy control volunteers (CTR) were included. ALS, PLS, CTR matched age sex. Plasma samples obtained...
Hydrophilic endogenous bile acids ursodeoxycholic acid (UDCA), tauroursodeoxycholic (TUDCA), and glucourosodeoxycholic (GUDCA) have suggested neuroprotective effects. We performed a case-control study to examine the association between ALS diagnosis serum levels of acids. Sporadic familial patients, age- sex-matched healthy controls, presymptomatic gene carriers who donated blood samples were included. Non-fasted stored at -80°C used for analysis. Serum measured by liquid chromatography-mass...
Epidemiologic studies suggest increasing incidence and prevalence of myasthenia gravis (MG) among the elderly population outside United States. We aimed to provide an estimation MG their trend Medicare Fee-For-Service (FFS)-covered US population.
Factors associated with coronavirus disease 2019 (COVID-19) infection among the myasthenia gravis (MG) population are incompletely understood. This study aimed to characterize behavior of MG patients during pandemic and examine risk factors COVID-19 infection.A "COVID-19 Survey" was sent Patient Registry participants in summer 2020 (CSS20) winter 2021 (CWS21). Survey results were summarized descriptively. Demographics, characteristics, medication use, survey compared between those reporting...
See article on pages 483–487 in this issue
Inflammatory and immune mechanisms are considered in restless legs syndrome (RLS) pathophysiology with several autoimmune diseases associated RLS. There is a paucity of studies examining RLS prevalence myasthenia gravis (MG), an neuromuscular disease. This study investigated association patient-reported measures large registry participants MG using validated diagnostic questionnaire.
To evaluate patient attitudes and beliefs toward thymectomy for myasthenia gravis (MG).
A 22-year-old woman with a history of sickle cell disease and migraine headaches presented weakness that had caused her to fall on the day admission. She reported gradual progression during previous 6 months, which led in few weeks difficulty standing, climbing steps, lifting child.
To describe the impact of COVID-19 in patients with myasthenia gravis (MG).