Wenda Zhong

ORCID: 0000-0003-0561-9702
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Research Areas
  • Electrocatalysts for Energy Conversion
  • Advanced battery technologies research
  • Advanced Photocatalysis Techniques
  • Nanoplatforms for cancer theranostics
  • Catalysis and Hydrodesulfurization Studies
  • Copper-based nanomaterials and applications
  • Photodynamic Therapy Research Studies
  • Adenosine and Purinergic Signaling
  • Supercapacitor Materials and Fabrication
  • Advancements in Battery Materials
  • Catalytic Processes in Materials Science
  • Nanoparticle-Based Drug Delivery
  • Immunotherapy and Immune Responses
  • Metal and Thin Film Mechanics
  • Advanced biosensing and bioanalysis techniques
  • Cancer, Hypoxia, and Metabolism
  • Click Chemistry and Applications
  • Ammonia Synthesis and Nitrogen Reduction
  • Endoplasmic Reticulum Stress and Disease
  • Autophagy in Disease and Therapy
  • Advanced Battery Materials and Technologies
  • Nanomaterials for catalytic reactions
  • RNA regulation and disease
  • Fuel Cells and Related Materials
  • RNA Interference and Gene Delivery

Weifang Medical University
2023-2025

Second Hospital of Shandong University
2025

Hunan University
2020-2023

China University of Geosciences
2016

Abstract Transition metal carbides (TMCs) feature high catalytic activity and superior stability for the hydrogen evolution reaction (HER). However, their platinum‐like HER performance is heavily hindered, due to strong interaction with hydrogen. Herein, Ni activation of TMCs (M = V, Fe, Cr, Mo) proposed through introducing adsorbed nickel atoms on TMC surface (Ni/TMC). In both acidic alkaline solutions, a sharp decrease overpotentials Tafel slopes Ni/TMC catalysts achieved. At 10 mA cm −2 ,...

10.1002/aenm.202002260 article EN cc-by-nc Advanced Energy Materials 2020-08-02

Abstract Surface self‐reconstruction via incorporating an amorphous structure on the surface of a catalyst can induce abundant defects and unsaturated sites for enhanced hydrogen evolution reaction (HER) activity. Herein, electrochemical activation method is proposed to reconstruct Cu‐Fe 3 O 4 catalyst. Following “dissolution–redeposition” path, defective FeOOH formed under potential stimulation precursor during process. This Cu‐FeOOH/Fe exhibits excellent stability as well extremely low...

10.1002/aenm.202200077 article EN cc-by-nc Advanced Energy Materials 2022-03-13

Molybdenum sulfide (MoS2) is a promising electrode material for supercapacitors; however, its limited Mo/S edge sites and intrinsic inert basal plane give rise to sluggish active electronic states, thus constraining electrochemical performance. Here we propose hierarchical confinement strategy develop ethylene molecule (EG)-intercalated Co-doped sulfur-deficient MoS2 (Co-EG/SV-MoS2) efficient durable K-ion storage. Theoretical analyses suggest that the intercalation-confined EG...

10.1021/acsnano.3c09386 article EN ACS Nano 2024-01-08

Abstract Efficient electrochemical overall water splitting requires bi‐functional catalysts that work for both hydrogen and oxygen evolution reactions (HER/OER). A heterostructure is thus proposed to maintain its optimal interactions with H/O‐containing intermediates. so‐called “orbital occupancy self‐equilibrium” strategy employed theoretically experimentally design such catalysts, namely the incorporation of V species into a NiS/NiS 2 heterostructure. Owing variable valences Ni species,...

10.1002/aenm.202300978 article EN Advanced Energy Materials 2023-07-04

Abstract Hydrogen production from water splitting is one of the most promising approaches to achieve carbon neutrality when high‐performance electrocatalysts are ready for sluggish hydrogen evolution reaction (HER). Although earth‐rich and cheap transition metal carbides (TMCs) potential HER electrocatalysts, their platinum‐like electronic structures severely hampered by strong binding with intermediates (H*). Here, a universal “balance effect” strategy proposed, where nitrogen‐doped...

10.1002/adfm.202108167 article EN cc-by-nc Advanced Functional Materials 2021-10-20

Abstract Cost‐effective transition metal sulfides (TMSs) are potential electrocatalysts for alkaline hydrogen evolution reaction (HER). However, free energies of intermediates adsorbed on the TMSs (e.g., iron sulfides) too negative, hindering their hydrogenase‐like catalytic activity. With an aim to improve inherently activity TMSs, design boron‐doped Fe 7 S 8 /FeS 2 (B‐Fe ) base density functional theory (DFT) calculation results is first conducted in this work. Boron atoms doped into found...

10.1002/adfm.202107802 article EN cc-by-nc Advanced Functional Materials 2021-11-06

Abstract Potassium‐ion battery (PIB) using a carbon‐based anode is an ideal device for electrochemical energy storage. However, the large atomic size of potassium ions inevitably leads to huge volume expansion and collapse anodes, resulting in severe capacity fading during long‐term cycling. Herein, silicon carbide‐derived carbon (SiC‐CDC) with controllable pore structure synthesized concise etching approach. It exhibits maximum 284.8 mA h g −1 at current density 0.1 A after 200 cycles as...

10.1002/adfm.202004348 article EN cc-by Advanced Functional Materials 2020-08-06

Abstract The universal preparation of noble metal single‐atom catalysts (NMSACs) is critical for efficient sustainable energy conversion. In this study, a versatile sowing strategy proposed to prepare the NMSACs with hyper‐low loading. A metal‐organic framework derived Ni(OH) x Ni 2+ vacancies serves as fertile soil plentiful trapping holes, where Pt atom seeds can be inserted. atoms tend form tetradentate Pt‐O 4 roots, confining loading concentration range (≈0.17 wt%). This Pt‐Ni(OH)...

10.1002/aenm.202203955 article EN cc-by-nc Advanced Energy Materials 2023-01-25

Abstract Immunotherapy represents a widely employed modality in clinical oncology, leveraging the activation of human immune system to target and eradicate cancer cells tumor tissues via endogenous mechanisms. However, its efficacy remains constrained by inadequate responses within “cold” microenvironment (TME). In this study, multifunctional nanoscale pyroptosis inducer with cascade enzymatic activity (IMZF), comprising superoxide dismutase (SOD), catalase (CAT), peroxidase (POD),...

10.1002/advs.202408729 article EN cc-by Advanced Science 2024-10-09

The introduction of Jahn–Teller distortion and electron redistribution afford Cu–Ni(OH) 2 with abundant active adsorption sites, facilitating the complete hydrogen evolution kinetics.

10.1039/d1ta05941f article EN Journal of Materials Chemistry A 2021-01-01

Abstract Multi‐drug resistance (MDR) is a major cause of cancer therapy failure. Photodynamic (PDT) promising modality that can circumvent MDR and synergize with chemotherapies, based on the generation reactive oxygen species (ROS) by photosensitizers. However, overproduction glutathione (GSH) cells scavenges ROS restricts efficacy PDT. Additionally, side effects normal tissues are unavoidable after PDT treatment. Here, to develop organic systems deliver effective anticancer chemotherapy...

10.1002/advs.202307765 article EN cc-by Advanced Science 2024-06-19

Despite significant clinical breakthroughs in anti-tumor immunotherapy, its therapy efficiency remains hindered by insufficient "cold" tumor immune responses. The ample reactive oxygen species photodynamic (PDT) can trigger the immunogenic cell death (ICD) pathway for arousing system and realizing immunotherapy. But inherent hypoxic microenvironment (TME) limits PDT efficacy. To simultaneously reverse TME promote ICD pathway, multi-in-one nanostructure (FAIC) is designed, which catalase...

10.1021/acsanm.4c05728 article EN ACS Applied Nano Materials 2025-01-01

Currently, immunotherapy based on photothermal and the application of photodynamic therapy in anti-tumor treatment is showing great potential. Its uniqueness lies critical role small molecule immunomodulators promoting effective immune responses against tumors, use laser-activated biophysical mechanisms to precisely trigger swift demise cancer cells, avoiding damage surrounding normal tissues. However, (PDT) alone hampered by tumors' hypoxic environment, resulting poor antitumor effects,...

10.1021/acsami.5c00184 article EN ACS Applied Materials & Interfaces 2025-03-28

The excessive production of reactive oxygen species (ROS) can damage the mitochondrial membrane and induce apoptosis, causing endoplasmic reticulum stress triggering immunogenic cell death. Therefore, combination apoptosis death by dual-targeted ROS generator has great potential to address inefficient cancer treatment. A near-infrared photosensitizer was developed for efficient Due modulation electron structure, reduced transition energy barrier affords TCy5-I-3F highest efficiency produce...

10.1016/j.matdes.2023.112566 article EN cc-by-nc-nd Materials & Design 2023-12-10
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