A5014941732- Nanoplatforms for cancer theranostics
- Industrial Vision Systems and Defect Detection
- Photoacoustic and Ultrasonic Imaging
- Integrated Circuits and Semiconductor Failure Analysis
- Advanced Radiotherapy Techniques
- Nanoparticle-Based Drug Delivery
- Photodynamic Therapy Research Studies
- AI and Big Data Applications
- Research studies in Vietnam
- Medical Image Segmentation Techniques
- Soft Robotics and Applications
- Advanced X-ray and CT Imaging
- RNA regulation and disease
- Ultrasound and Hyperthermia Applications
- Endoplasmic Reticulum Stress and Disease
- Pharmacological Effects of Natural Compounds
- Optical Systems and Laser Technology
- Lung Cancer Diagnosis and Treatment
- Adaptive optics and wavefront sensing
- Medical Imaging Techniques and Applications
- Heme Oxygenase-1 and Carbon Monoxide
- Circular RNAs in diseases
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Measurement and Metrology Techniques
- Cancer Immunotherapy and Biomarkers
Weifang Medical University
2024-2025
University of South China
2022
Third Affiliated Hospital of Southern Medical University
2020-2021
Wuchang University of Technology
2021
Qufu Normal University
2020
Qingdao University
2019
Qingdao Municipal Hospital
2019
Columbia University
2011-2016
Cornell University
2011
NewYork–Presbyterian Hospital
2011
Because of its high tissue penetrative depth, remote spatiotemporal selectivity, and noninvasive therapeutic features, sonodynamic therapy (SDT) has received much attention in recent years. In the SDT, a tumor-localizing sonosensitizing agent is activated by ultrasound produces greatly reactive oxygen species (ROS) to kill tumor cells. Sonosensitizers, including some organic/inorganic compounds micro/nanoscale sonosensitizers, are an important element SDT. Herein, we will introduce...
Abstract Immunotherapy represents a widely employed modality in clinical oncology, leveraging the activation of human immune system to target and eradicate cancer cells tumor tissues via endogenous mechanisms. However, its efficacy remains constrained by inadequate responses within “cold” microenvironment (TME). In this study, multifunctional nanoscale pyroptosis inducer with cascade enzymatic activity (IMZF), comprising superoxide dismutase (SOD), catalase (CAT), peroxidase (POD),...
Abstract The antioxidant defense system in malignant cells, which involves enzymes and molecules, is an innate barrier to photodynamic therapy (PDT). Because of the complexity endogenous mechanisms these simply inhibiting individual pathways has a limited effect on improving lethality ROS. To enhance efficacy PDT for tumor treatment, versatile nanoparticle (NP)‐based drug developed, authors call PZB NP, containing glutathione inhibitor l ‐buthionine sulfoximine (BSO) heme oxygenase 1 (HO‐1)...
Despite significant clinical breakthroughs in anti-tumor immunotherapy, its therapy efficiency remains hindered by insufficient "cold" tumor immune responses. The ample reactive oxygen species photodynamic (PDT) can trigger the immunogenic cell death (ICD) pathway for arousing system and realizing immunotherapy. But inherent hypoxic microenvironment (TME) limits PDT efficacy. To simultaneously reverse TME promote ICD pathway, multi-in-one nanostructure (FAIC) is designed, which catalase...
Currently, immunotherapy based on photothermal and the application of photodynamic therapy in anti-tumor treatment is showing great potential. Its uniqueness lies critical role small molecule immunomodulators promoting effective immune responses against tumors, use laser-activated biophysical mechanisms to precisely trigger swift demise cancer cells, avoiding damage surrounding normal tissues. However, (PDT) alone hampered by tumors' hypoxic environment, resulting poor antitumor effects,...
Radix Aconiti Lateralis Preparata (Fuzi) is a traditional Chinese medicine. Its alkaloids are both cardiotonic and cardiotoxic; however, the underlying mechanisms unclear. Compatibility testing processing primary approaches used to reduce toxicity of aconite preparations. The purpose this study was compare effects crude Fuzi (CFZ), CFZ combined with Glycyrrhiza (Gancao) (CFZ+GC), prepared materials (PFZ) on heart failure (HF) in C57BL/6J mice explore potential action CFZ. Transverse aortic...
The circular RNA circ-PRKCI is an endogenous non-coding that forms a covalently closed ring after reverse splicing, which plays key role in the occurrence and development of multiple digestive system tumors.To investigate mechanism hepatocellular carcinoma (HCC).This study used real-time polymerase chain reaction to detect expression tumor tissues, adjacent blood patients with HCC other cells. A series functional tests were performed explore whether affects growth cells what its HCC....
A versatile tumor targeting theranostic nanoagent (named T-lipos-CPAuNCs) was introduced to realize multimodal imaging-guided cancer photothermal therapy with suppression of the inflammatory response.
Solder joint inspection has traditionally been done by manual inspection. The disadvantage of is the large amount time required and decrease in efficiency as operator fatigue occurs. This prompted development automated systems to speed up process increase efficiency. Automated typically use visible light, infrared light or X-rays illuminate board. These require solder position information that provided either CAD data human entry information. paper describes a preliminary, system finds...
The effects of disk radial tilt on the differential time detection (DTD) tracking error signal are calculated and measured. A new scheme is proposed, which uses only one focus beam four detectors namely, A, B, C D quadrants. Experimental results show that method exhibits good linearity with a sensitivity about 320 mV/degree in range -0.5°–+0.5°.
This paper describes a preliminary, automated inspection system that finds the solder joints in X-ray image and inspects them using an artificial neural network (ANN). The identification of gray-scale is done processing techniques; CAD data or manual registration not required. techniques also yield binary maps (i.e. black white images) showing locations ICs other components, which useful for diagnostics.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Purpose: Prostate brachytherapy is an effective treatment for early prostate cancer. The current implant limited to using 2D transrectal ultrassound (TRUS) or machenical motor driven array either in the end on side. Real‐time 3D images can improve accuracy of guidance implant. concept our system allow realtime full visualization entire with multiple transverse scan. Methods: prototype Multiple‐Transverse‐Plane Transrectal Ultrasound probe (MTP‐TRUS) has been designed by us and manufactured...
Purpose: A metallic instrument usually has much higher acoustic impedance than the surrounding tissue. Thus reflections from appear as high intensity pixels in ultrasound image. Acoustic shadows, attenuation and other artifacts can also locally obscure continuous appearance of instrument. Moreover, specific such a needle with hole inside used prostate brachytherapy, generate strong reverberation artifacts. The stemmed metal interference adversely affect image quality lead to erroneous...
Purpose: The accuracy of delivering gated‐radiation therapy to lung tumors using an external respiratory surrogate relies on the degree correlation between marker serving as a from breathing and motion anatomic structures. irregular during imaging treatment session one another may cause dose distribution actually delivered be different intended dose. purpose this work was use diaphragm images acquired Ultrasound system abdominal signal Real‐time Position Management (RPM) system, study...
The single-degree-of-freedom and three-degree-of-freedom viscous damping systems are simulated based on the Morlet wavelet function transformation in an effort to study transform further promote optimization of nonlinear system modal identification. In meantime, animation display technology is studied using Visual Basic (VB) 6.0 software Open GL three-dimensional graphics library. research object a thin plate member with five degrees freedom. results as follows. system, identification...
Textures are degraded by Gaussian noise in the process of image acquisition. The restoration a texture is very important for later analysis and classification. In this paper, method ranked residuals proposed to restore binary which corrupted noise. This not only deletes but also preserves all details texture. addition, it has property preserving any line endings (not necessarily straight) boundary (concave or convex) at orientation, edges, corners. main idea residual that selects windowed...