A5021537351- Lung Cancer Diagnosis and Treatment
- Asthma and respiratory diseases
- Cancer Immunotherapy and Biomarkers
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Urinary Tract Infections Management
- Immunotherapy and Immune Responses
- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Cardiac Valve Diseases and Treatments
- Medical Imaging and Pathology Studies
- Gut microbiota and health
- IL-33, ST2, and ILC Pathways
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Aortic Disease and Treatment Approaches
- Pleural and Pulmonary Diseases
- COVID-19 Clinical Research Studies
- Bladder and Urothelial Cancer Treatments
- Lung Cancer Treatments and Mutations
- Glycosylation and Glycoproteins Research
- Inflammatory Biomarkers in Disease Prognosis
- Venous Thromboembolism Diagnosis and Management
- RNA modifications and cancer
- Air Quality and Health Impacts
- Ultrasound in Clinical Applications
Ningbo University
2023-2025
Ningbo First Hospital
2018-2025
Sichuan University
2020-2022
West China Hospital of Sichuan University
2020-2022
Shanghai Public Security Bureau
2021
Southern Medical University
2015-2019
Nanfang Hospital
2018-2019
Hebei Medical University
2016-2018
Fourth Hospital of Hebei Medical University
2016-2018
University of Electronic Science and Technology of China
2014
Mounting evidence indicates that microbiome plays an important role in the development and progression of cancer. The dogma urine healthy individuals must be sterile has been overturned. Dysbiosis urinary revealed responsible for various urological disorders, including prostate link between chronic inflammation, solid tumors established neoplastic diseases. However, a detailed comprehensive analysis microenvironment bladder cancer not yet reported. We performed this study to characterize...
Perturbation of the microbiome has numerous associations with phenotypes and progression in chronic airways disease. However, differences nasal asthma allergic rhinitis (AR) have not been defined. We examined whether would vary among different comorbidities AR that those may be associated severity asthma. Nasal lavage fluid was collected from 110 participants, including 20 healthy controls, 30 subjects AR, combined + AR. The Asthma Control Questionnaire (ACQ-7) used to evaluate control...
Objective The aim of this research was to explore the possible connection between combined Oxidative Balance Score (OBS) and prevalence chronic inflammatory airway diseases (CIAD), including asthma, obstructive pulmonary disease (COPD), bronchitis, along with mortality rate among individuals CIAD. Methods Data were gathered from National Health Nutrition Examination Survey (NHANES) 2013–2018 cycles. calculated using 16 different nutrients 4 lifestyles, which then categorized into four...
ABSTRACT Background Food insecurity (FI) has been a global threat, as social determinant in connection with the prevalence of diseases requiring dietary interventions, such asthma, established. This study aims to examine relationship between FI and respiratory health outcomes. Methods cross‐sectional included 7626 children 17 530 adults from 2007 2012 National Health Nutritional Examination Surveys (NHANES) United States. Weighted multivariate regression models were used evaluate...
Colon cancer is one of the most common, lethal diseases worldwide. Tumor metastasis and chemotherapy resistance are main reasons for its poor prognosis high fatality rate. development thought as complex cellular events it a multi-step cascading process involving infinite proliferation, invasion immigration. Recently, increasing studies have demonstrated that microRNA-126 (miR-126) has an important role in colon cancer. The expression miR-126 decreased significantly cancer, particularly...
As the best characterised cancer/testis antigen family members, melanoma-associated antigens (MAGE) have been reported to be expressed in various malignant tumours. However, expression pattern of MAGE-A lung adenocarcinoma (LAC) specimens and their prognostic therapeutic significance for patients with LAC is still unclear.Tissue microarray-based immunohistochemistry analysis was used examine members (including MAGE-A1, A2, A3, A4, A6, A10, A11 A12) 105 paired corresponding pericarcinoma...
Lower urinary tract symptoms (LUTS) is the most common complication of diabetes. However, underlying pathogenesis cultured negative LUTS (cn-LUTS) in diabetic patients has not been well understood. Numerous evidence indicates that dysbiosis related to urologic disorders. We aim study alterations microbiota cn-LUTS type 2 diabetes (T2D) patients. Female T2D and controls were recruited requested finish American Urological Association Symptom Index. Mid-stream urine was collected for culturing...
Abstract This paper proposes a safety evaluation model of inland waterway ship navigation based on the fuzzy theory and evidential reasoning (ER) approach. The proposed is three-level hierarchical system consisting 18 indicators that are identified determined through literature review expert surveys. By using theory, factors index level converted into belief distributions, information within each merged by ER approach so ship's can be realized. deal with multi-source both qualitative...
The objective of this study was to investigate the potential association between inflammatory burden index (IBI) and prevalence chronic airway diseases (CIAD), as well mortality rates among individuals diagnosed with CIAD.
Recently, we have reported that the product of Melanoma Antigens Genes (MAGE) family member MAGE-A11 is an independent poor prognostic marker for esophageal squamous cell carcinoma (ESCC). However, reason how activated in ESCC progression still remains unclear. In current study, demonstrated DNA methylation and subsequent histone posttranslational modifications play crucial roles regulation progression. We found rate TFCP2/ZEB1 binding site on promoter tissues cells higher than normal...
Objective: The aim of the present study was to explore diagnostic value and safety color Doppler ultrasound (US)-guided transthoracic core needle biopsy (CNB) peripheral lung, chest wall mediastinal lesions using automated guns.Materials methods: We analyzed clinical image data, histopathologic microbiologic details complications from 121 patients with who underwent US-guided CNB in Ningbo First Hospital between January 2015 June 2018.Results: Color performed a freehand technique guns had...
Presently, there are limited reports in the literature on postoperative (midterm) clinical outcome for pure aortic regurgitation (AR) following transcatheter valve replacement (TAVR).Between March 2014 and June 2019, a total of 134 high-risk patients with pure, symptomatic severe AR were enrolled current study. The was assessed according to Valve Academic Research Consortium-2 criteria. Procedural results, outcomes, patients' hemodynamics period 1 year analyzed.The patient mean 73.1 ± 6.4...
Background MAGE‐A genes belong to the cancer/testis antigens family. The prognostic significance of expression in peripheral blood patients with lung cancer is unknown. Therefore, this study evaluated and possible cancer. Methods In study, we detected gene 150 30 healthy donors using multiplex semi‐nested PCR analyzed their correlation clinicopathological risk factors. Results was associated factors indicating poor prognosis. each individual were also low overall survival Conclusion may act...
To investigate the risk factors of pulmonary embolism in patients with lung cancer and develop validate a novel nomogram scoring system-based prediction model.We retrospectively analyzed clinical data laboratory characteristics 900 who were treated, including without (LC) (LC + PE). The randomly divided into derivation internal validation groups 7:3 ratio. Using logistic regression analysis, diagnostic model system was developed by incorporating selected variables group validated external (n...
Melanoma-associated antigen-A11 (MAGE-A11) is frequently expressed in breast cancer and associated with poor prognosis. Therefore, MAGE-A11 a potential immunotherapy target cancer. expression, however, downregulated many patients, thus constraining the application of immunotherapy. The induction expression crucial for recognition killing cells by cytotoxic T lymphocytes (CTL). In this study, series HLA-A2-restricted candidate peptides were predicted, synthesized, tested. Of selected...
Abstract Background This study was performed to investigate clinical features of patients with severe SARS-CoV-2 pneumonia and identify risk factors for converting cases in those who had mild moderate diseases at the start pandemic China. Methods In this retrospective, multicenter cohort study, were included. Demographic data, symptoms, laboratory values, outcomes collected. Data compared between non-severe patients. Results 58 included final analysis. Compared cases, a longer: time recovery...
Objective The aim of this study was to develop and validate Chinese versions the International Consultation on Incontinence Modular Questionnaire for Male Lower Urinary Tract Symptoms (ICIQ‐MLUTS) ICIQ‐MLUTS Long Form (LF), discuss their potential functions. Methods original LF were translated into after obtaining permission from Advisory Board. Between November 2017 August 2018, validated by administering them male patients with lower urinary tract symptoms attending urology department in 6...