Linfeng Wang

ORCID: 0000-0002-0074-6043
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Spinal Fractures and Fixation Techniques
  • Cervical and Thoracic Myelopathy
  • Scoliosis diagnosis and treatment
  • Medical Imaging and Analysis
  • Bone and Joint Diseases
  • Pelvic and Acetabular Injuries
  • Spinal Hematomas and Complications
  • Bone health and osteoporosis research
  • Musculoskeletal pain and rehabilitation
  • Spinal Cord Injury Research
  • Radiomics and Machine Learning in Medical Imaging
  • Spondyloarthritis Studies and Treatments
  • Tendon Structure and Treatment
  • Medical Imaging and Pathology Studies
  • Shoulder Injury and Treatment
  • Tuberculosis Research and Epidemiology
  • Hemostasis and retained surgical items
  • Nerve Injury and Rehabilitation
  • Helicobacter pylori-related gastroenterology studies
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Pharmaceutical Practices and Patient Outcomes
  • Heterotopic Ossification and Related Conditions
  • Hip and Femur Fractures
  • Pregnancy-related medical research

Third Hospital of Hebei Medical University
2016-2025

Hebei Medical University
2016-2025

First Affiliated Hospital of Jiangxi Medical College
2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2025

Guang’anmen Hospital
2025

Henan University
2025

Peking University
2025

Nanchang University
2025

Xiangya Hospital Central South University
2020-2024

Anhui Jianzhu University
2024

Retrospective study.To investigate whether magnetic resonance imaging-based vertebral bone quality (VBQ) score can predict pedicle screw loosening in patients who underwent fixation, and to compare, which measurement, the VBQ or Hounsfield unit (HU) value, is more predictive of loosening.In clinical work, we found that with had higher scores. In addition, some studies have a correlation between scores osteoporosis.Patients were treated lumbar fixation reviewed. The was measured using imaging...

10.1097/brs.0000000000004577 article EN cc-by-nc-nd Spine 2023-01-19

To investigate the long-term impacts of different posterior operations on curvature, neurological improvement and axial symptoms for multilevel cervical degenerative myelopathy (CDM), to study relationship among loss lordosis, recovery rate symptom severity.We retrospectively reviewed 98 patients with CDM who had undergone laminoplasty (Group LP, 36 patients), laminectomy LC, 30 or lateral mass screw fixation LCS, 32 patients) between January 2000 2005. Loss curvature index (CI) was measured...

10.1007/s00586-013-2741-5 article EN cc-by European Spine Journal 2013-03-18

Perturbation of the microbiome has numerous associations with phenotypes and progression in chronic airways disease. However, differences nasal asthma allergic rhinitis (AR) have not been defined. We examined whether would vary among different comorbidities AR that those may be associated severity asthma. Nasal lavage fluid was collected from 110 participants, including 20 healthy controls, 30 subjects AR, combined + AR. The Asthma Control Questionnaire (ACQ-7) used to evaluate control...

10.3389/fcimb.2022.841995 article EN cc-by Frontiers in Cellular and Infection Microbiology 2022-03-03

Background: Bone-tendon injury is characterized by poor self-healing. It established that exosomes are favorable for tissue repair and regeneration. However, their effect on bone-tendon healing has not yet been determined. Purpose: To compare the effectiveness of derived from adipose-derived mesenchymal stromal cells (ADSC-Exos) bone marrow–derived (BMSC-Exos) interface in murine rotator cuff model explore underlying mechanisms thereof. Study Design: Controlled laboratory study. Methods: A...

10.1177/23259671231210304 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2024-01-01

A retrospective imaging study of 73 patients who underwent surgery for cervical spondylotic myelopathy (CSM) between April 2005 and July 2007.To investigate whether magnetic resonance (MR) T2 image signal intensity (SI) ratio clinical manifestation can assess the prognosis in with CSM.The association intramedullary high SI on T2-weighted MR images surgical outcome CSM remains controversial. The means quantizing disease has not been discussed.A total compressive were retrospectively enrolled...

10.1097/brs.0b013e3181c6dbc4 article EN Spine 2010-04-13

Purpose: The purpose of this study was to compare the clinical efficacy and safety percutaneous vertebroplasty (PVP) kyphoplasty (PKP) in treatment elderly with very severe osteoporotic vertebral compression fractures (vsOVCFs). Methods: From September 2012 2015, 57 patients vsOVCFs who had undergone PVP PKP surgeries at our medical center were reviewed retrospectively, least 2 years follow-up. All divided into group (n=31) (n=26). Clinical data including radiological evaluation results...

10.2147/jpr.s179022 article EN cc-by-nc Journal of Pain Research 2018-10-01

ABSTRACT Amplicon sequencing (Amp-Seq) of Mycobacterium tuberculosis genes associated with drug resistance and strain typing offers a cost-effective approach for profiling infections tailoring the clinical management tuberculosis. However, Amp-Seq assays require continual updates to incorporate new loci mutations linked resistance. We introduce TOAST (Tuberculosis Optimised Sequencing Tool), customisable software tool that optimises amplicon design across any platforms (e.g., Illumina,...

10.1101/2025.01.13.632698 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2025-01-15

Introduction “Sweating,” a key step in the processing and production of Eucommiae Cortex (EC), which plays vital role formation medicinal quality EC. However, mechanism effect this traditional treatment herbs on is still unclear. Methods In study, high performance liquid chromatography (HPLC), UPLC/MS-based untargeted metabolomics high-throughput sequencing were applied to investigate dynamic changes main active ingredients, differential metabolites bacterial communities process “sweating”...

10.3389/fmicb.2025.1550337 article EN cc-by Frontiers in Microbiology 2025-02-28

Study Design. A multi-center retrospective cohort study Objective. To overcome the limitations of former single-center strategy studies, an updated classification guiding surgical management Atlantoaxial dislocation (AAD) is proposed in this based on a large with mid-to-long-term follow-up. Summary Background Data. AAD most prevalent disorder affecting cranio-vertebral junction, often leading to myelopathy and impairment cranial nerve function, which can result significant morbidity or even...

10.1097/brs.0000000000005318 article EN Spine 2025-02-26

Abstract Periosteal stem cells are critical for bone regeneration, while the numbers will decrease with age. This study focused on whether Prx1 + cell, a kind of periosteal could stimulate regeneration in aged mice. Four weeks and 12 months old Prx1CreER‐GFP; Rosa26 tdTomato mice were used to reveal degree participating femoral fracture healing procedure. One week, 8 weeks, 24 Prx1CreER‐GFP analyse real‐time distribution cells. Twelve C57BL/6 male (n = 96) create defect model and,...

10.1111/jcmm.15891 article EN cc-by Journal of Cellular and Molecular Medicine 2020-09-15

To observe the effects of vitamin D on apoptotic human nucleus pulposus cells under tumor necrosis factor-α (TNF-α) treatment.The gene expression data was downloaded from NCBI Gene Expression Omnibus (GEO) database ( https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE34095 ). Differentially expressed genes between degenerative disc and non-degenerative were performed by R software. ontology (GO) Kyoto Encyclopedia Genes Genome (KEGG) pathway enrichment analyses using The Database for...

10.1186/s13018-021-02545-9 article EN cc-by Journal of Orthopaedic Surgery and Research 2021-06-28

The fusion of the lumbar spine may lead to degeneration adjacent segments. In this study, effects OLIF and TLIF on segments after treatment L4 degenerative spondylolisthesis (DLS) were compared analysed.This was a retrospective analysis medical records consecutive patients treated with or for L4DLS. They divided into group based different methods. Cage height, segmental lordosis (SL), (LL), pelvic incidence (PI), tilt (PT), sacral slope (SS) between two groups, postoperative biomechanical...

10.1186/s13018-022-03084-7 article EN cc-by Journal of Orthopaedic Surgery and Research 2022-04-04

The aim of this study was to investigate the clinical significance both signal intensity ratio obtained from MR imaging and manifestations on prognosis patients with cervical ossification posterior longitudinal ligament.The authors retrospectively reviewed records 58 ligament who underwent laminoplasty February 1999 July 2007. Magnetic resonance (1.5-T) performed in all before surgery. Sagittal T2-weighted images spinal cord compressed by ossified showed increased intramedullary intensity,...

10.3171/2010.3.spine09887 article EN Journal of Neurosurgery Spine 2010-09-01

The optimal management approach for patients with mild forms of cervical spondylotic myelopathy (MCSM) has not been well established. aim the present study was to investigate outcome conservative treatment, identify prognostic factors and provide evidence timing surgical intervention. A total 90 MCSM attending hospital between February 2007 January 2009 were prospectively enrolled. Initially, all received treatment followed up periodically. When a deterioration in clearly identified,...

10.3892/etm.2013.1224 article EN Experimental and Therapeutic Medicine 2013-07-16

Abstract Postoperative exercise has been found able to accelerate bone‐tendon (B‐T) healing. In this study, we systematically compared tendon‐to‐bone healing in mice subjected postoperative treadmill and free cage recovery a murine rotator cuff repair model. Specifically, C57BL/6 underwent unilateral supraspinatus tendon (SST) detachment were randomly allocated into group control group. Treadmill received daily running initiated from day 7 while the was allowed activity. Mice euthanized at 4...

10.1002/jor.24678 article EN Journal of Orthopaedic Research® 2020-04-02

The timely identification of individuals at high risk for peptic ulcers (PUs) is vital in preventing gastrointestinal bleeding after antiplatelet therapy. This study was designed to determine PU factors and develop a assessment model detection the general Chinese population. In prospective dataset, clinical data from undergoing gastroscopic evaluation between April 2019 May 2022 were recorded. PUs defined as mucosal defects exceeding 5 mm confirmed via gastroscopy. Participants categorized...

10.1038/s41598-024-55224-0 article EN cc-by Scientific Reports 2024-02-23
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