Xiujun Han

ORCID: 0000-0003-0581-513X
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About
Contact & Profiles
Research Areas
  • Pregnancy and preeclampsia studies
  • Maternal and Perinatal Health Interventions
  • Birth, Development, and Health
  • Biomarkers in Disease Mechanisms
  • Virus-based gene therapy research
  • Prenatal Screening and Diagnostics
  • Gynecological conditions and treatments
  • Pregnancy-related medical research
  • Assisted Reproductive Technology and Twin Pregnancy
  • Female Genital Mutilation/Cutting Issues
  • Medical Research and Treatments
  • Grief, Bereavement, and Mental Health
  • Uterine Myomas and Treatments
  • Child Nutrition and Feeding Issues
  • Maternal and fetal healthcare
  • Kruppel-like factors research
  • Breastfeeding Practices and Influences
  • Maternal Mental Health During Pregnancy and Postpartum
  • Reproductive System and Pregnancy
  • CAR-T cell therapy research
  • T-cell and Retrovirus Studies
  • COVID-19 Impact on Reproduction
  • RNA Interference and Gene Delivery
  • Histone Deacetylase Inhibitors Research
  • Viral Infectious Diseases and Gene Expression in Insects

Women's Hospital, School of Medicine, Zhejiang University
2016-2025

Zhejiang University
2012-2014

To determine whether maternal serum markers in the early second trimester are useful for prediction of gestational diabetes mellitus (GDM).A total 876 singleton pregnancies were recruited present study. Blood samples collected during 16-20 weeks. GDM women diagnosed by an oral glucose tolerance test 24-28 A 56 with and 73 healthy pregnant selected. Maternal concentrations placental protein 13 (PP13), pentraxin 3 (PTX3), soluble fms-like tyrosine kinase-1 (sFlt-1), myostatin follistatin (FST)...

10.1111/jdi.12798 article EN cc-by-nc Journal of Diabetes Investigation 2017-12-30

To determine whether late second-trimester maternal serum biomarkers are useful for the prediction of preeclampsia during third trimester, a case-control study including 33 preeclamptic and 71 healthy pregnancies was conducted. Maternal concentrations placental protein 13 (PP13), pregnancy-associated plasma (PAPP-A), pentraxin3 (PTX3), soluble FMS-like tyrosine kinase-1 (sFlt-1), myostatin follistatin-like-3 (FSLT-3) were measured at 24-28 weeks' gestation. All these markers compared between...

10.1515/jpm-2016-0249 article EN Journal of Perinatal Medicine 2016-12-09

Oncolytic adenoviruses (OA) have been investigated as virotherapeutic agents for the treatment of cervical cancer and thus far results are promising. However, cytotoxicity viruses requires improvement. The present study demonstrated that this can be achieved by combining ZD55‑TRAIL, an OA containing tumor necrosis factor‑related apoptosis‑inducing ligand (TRAIL) gene, with histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA). It was these act synergistically to kill HeLa...

10.3892/mmr.2015.3355 article EN Molecular Medicine Reports 2012-02-16

Objective: To determine whether serum Follistatin-like-3 was enhanced in second trimester of pregnant women who subsequently developed preeclampsia. Methods: Thirty-nine preeclampsia and 73 normal pregnancy were included. Serum samples taken 24–28 weeks gestation used for assay Follistatin-like-3. Results: significantly elevated group compared with control. However, there no significant difference mild or severe Conclusion: The elevation demonstrated late destined to developing preeclampsia,...

10.3109/10641955.2013.874439 article EN Hypertension in Pregnancy 2014-01-29

To investigate the risk factors of intra-amniotic infection (IAI) related to induction with single-balloon catheter (SBC).A retrospective, case-control study including 58 cases IAI patients who underwent SBC was conducted in Women's Hospital, School Medicine, Zhejiang University. For each case, 8 women delivered during same month and had no after were selected for control.Compared control group, group a higher rate nulliparity (87.93 vs. 70.69%; p = 0.006), BMI > 30 kg/m2 (29.31 15.95%;...

10.1159/000493795 article EN Gynecologic and Obstetric Investigation 2018-10-17

Background: Pregnancies in women with a unicornuate uterus are associated an increased risk for specific adverse pregnancy and obstetric outcomes. We sought to investigate the outcomes of singleton pregnancies nulliparous third-trimester determine safe appropriate modes delivery. Methods: This retrospective cohort study included 94 uterus, along 278 matched controls normally shaped from March 2009 2019. Results: A total 124 patients were diagnosed obstetrics department after 28th week...

10.31083/j.ceog5111251 article EN cc-by Clinical and Experimental Obstetrics & Gynecology 2024-11-19

Introduction Though evidence has revealed the beneficial effects of cognitive improvement interventions on breastfeeding, effect psychological rarely been studied. This study aims to test whether promoting a positive emotion intervention, ‘Three Good Things’ during last trimester pregnancy can enhance early colostrum secretion and breastfeeding behaviours by modulating hormones associated with lactation (prolactin insulin-like growth factor I). We will attempt promote exclusive using...

10.1136/bmjopen-2022-066601 article EN cc-by BMJ Open 2023-06-01

Abstract: Aim: To investigate the clinical characteristics and outcome of twin pregnancies complicated by single intrauterine death how to improve outcomes surviving twins. Three thousand three hundred eighty-four women who delivered at Women’s Hospital, Zhejiang University, School Medicine were included. Clinical demographic data on gestational age, etiology, morbidity mortality for mothers fetuses collected. Results: The median age detecting a in pregnancy was 29 weeks average termination...

10.1515/jpm-2017-0008 article EN Journal of Perinatal Medicine 2017-03-15
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