A5089445276- Nuclear Structure and Function
- RNA Research and Splicing
- Traumatic Ocular and Foreign Body Injuries
- RNA modifications and cancer
- Cardiac Arrhythmias and Treatments
- DNA Repair Mechanisms
- Social Media in Health Education
- Health and Medical Research Impacts
- Health Literacy and Information Accessibility
- Endoplasmic Reticulum Stress and Disease
- Pulmonary Hypertension Research and Treatments
- Child Abuse and Related Trauma
- scientometrics and bibliometrics research
- Global Health Care Issues
- Primary Care and Health Outcomes
- Healthcare Policy and Management
- Cardiac Arrest and Resuscitation
- Meta-analysis and systematic reviews
- Mitochondrial Function and Pathology
- Patient-Provider Communication in Healthcare
- Disaster Response and Management
- Cardiovascular Issues in Pregnancy
- Intraocular Surgery and Lenses
Rutgers, The State University of New Jersey
2024-2025
Rutgers New Jersey Medical School
2024-2025
Thomas Jefferson University
2023-2024
Boston Medical Center
2024
Boston University
2024
Saint Barnabas Medical Center
2024
Lake Erie College of Osteopathic Medicine
2024
St. Joseph’s University Medical Center
2024
National Hospital
2022
Yale University
2022
Mutations in the LMNA gene encoding lamins A/C cause an array of tissue-selective diseases, with heart being most commonly affected organ. Despite progress understanding perturbations emanating from mutations, integrative pathogenesis underlying cardiac dysfunction remains elusive. Using a novel conditional deletion model capable translatome profiling, we observed that cardiomyocyte-specific Lmna adult mice led to rapid cardiomyopathy pathological remodeling. Before dysfunction, -deleted...
To characterize the epidemiology of consumer product-related ocular injury in United States (US) incarcerated population, and identify preventable causes. The National Electronic Injury Surveillance System (NEISS) database was queried for cases eye from 2014 to 2023. Incarcerated were identified using keywords "prison", "jail", "inmate", "incarcerate". Year injury, diagnosis, product code, demographic information gathered compared between general US populations SPSS version 29 (IBM Corp.). A...
ABSTRACT Introduction This study evaluates the readability of online patient education materials (OPEMs) across otolaryngology subspecialties, hospital characteristics, and national organizations, while assessing AI alternatives. Methods Hospitals from US News Best ENT list were queried for OPEMs describing a chosen surgery per subspecialty; American Academy Otolaryngology—Head Neck Surgery (AAO), Laryngological Association (ALA), Ear, Nose, Throat United Kingdom (ENTUK), Canadian Society...
Mediator 25 (Med25) is a member of the mediator complex that relays signals from transcription factors to RNA polymerase II machinery. Multiple factors, particularly those involved in lipid metabolism, utilize complex, but how Med25 this context unclear. We previously identified translatome screen adult cardiomyocytes (CMs) novel cell type-specific model LMNA cardiomyopathy. In study, we show upregulation coincident with myocardial accumulation. To ascertain role accumulation, utilized...
Abstract Mutations in the LMNA gene encoding nuclear lamins A/C cause a diverse array of tissue-selective diseases, with heart being most commonly affected organ. Despite progress understanding molecular perturbations emanating from mutations, an integrative pathogenesis leading to cardiac dysfunction remains elusive. Using novel cell-type specific Lmna deletion mouse model capable translatome profiling, we found that cardiomyocyte-specific adult mice led rapid cardiomyopathy pathological...
Introduction Pre-eclampsia is a pregnancy-associated multisystem disorder; in rare cases, it can be complicated by arrhythmias such as ventricular tachycardia (VT). The purpose of this study was to determine the prevalence and predictors VT among patients admitted with pre-eclampsia well analyze independent association in-hospital outcomes population. Methods Data were obtained from National Inpatient Sample January 2016 December 2019. Patients primary diagnosis selected using International...
Purpose The objective of this study was to evaluate the relationship between research activity and National Institutes Health (NIH) funding status United States (US) academic ophthalmologists.
Mutations in the LMNA gene encoding nuclear lamins A/C cause a diverse array of tissue-selective diseases, with heart being most commonly affected organ. Despite progress understanding molecular perturbations emanating from mutations, an integrative pathogenesis leading to cardiac dysfunction remains elusive. Nuclear envelope damage resulting mutations is widely observed and accepted be involved disease but how it contributes not well understood. To this end, we performed detailed kinetic...