Chaicharn Pothirat

ORCID: 0000-0003-0616-7066
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About
Contact & Profiles
Research Areas
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Asthma and respiratory diseases
  • Respiratory Support and Mechanisms
  • Respiratory and Cough-Related Research
  • Air Quality and Health Impacts
  • COVID-19 Clinical Research Studies
  • Pneumonia and Respiratory Infections
  • Climate Change and Health Impacts
  • Inhalation and Respiratory Drug Delivery
  • SARS-CoV-2 and COVID-19 Research
  • Sepsis Diagnosis and Treatment
  • Nosocomial Infections in ICU
  • Long-Term Effects of COVID-19
  • Venous Thromboembolism Diagnosis and Management
  • Allergic Rhinitis and Sensitization
  • Intensive Care Unit Cognitive Disorders
  • Antibiotic Resistance in Bacteria
  • Influenza Virus Research Studies
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Nursing Diagnosis and Documentation
  • Pediatric health and respiratory diseases
  • COVID-19 and Mental Health
  • Air Quality Monitoring and Forecasting
  • Balance, Gait, and Falls Prevention
  • SARS-CoV-2 detection and testing

Chiang Mai University
2016-2025

Pulmonary and Allergy Associates
2024

Songklanagarind Hospital
2003

To determine the safety and efficacy of recombinant thrombomodulin (ART-123) in patients with suspected sepsis-associated disseminated intravascular coagulation.Phase 2b, international, multicenter, double-blind, randomized, placebo-controlled, parallel group, screening trial.Two hundred thirty-three ICUs 17 countries.All adult admitted sepsis coagulation as assessed using a modified International Society on Thrombosis Hemostasis score.Patients were randomized to receive IV ART-123 (0.06...

10.1097/ccm.0b013e31828e9b03 article EN Critical Care Medicine 2013-08-27

Evaluating inhaler use technique in COPD patients Chaicharn Pothirat, Warawut Chaiwong, Nittaya Phetsuk, Sangnual Pisalthanapuna, Nonglak Chetsadaphan, Woranoot Choomuang Division of Pulmonary, Critical Care and Allergy, Department Internal Medicine, Faculty Chiang Mai University, Mai, Thailand Background: Poor inhalation techniques are associated with decreased medication delivery poor disease control chronic obstructive pulmonary (COPD). The purpose this study was to evaluate for using...

10.2147/copd.s85681 article EN cc-by-nc International Journal of COPD 2015-07-01

Chiang Dao is one of the districts in Mai, Thailand facing high level seasonal air pollution every year, exposure community dwellers to outdoor pollutants 24 hours a day during smog period because their open-air housing style, and agricultural occupational hazard. In addition, hospital only available serving with wards; therefore we could certainly identify association between mortality hospitalized patients. Thus, aim this study was determine daily average patients as well emergency...

10.21037/jtd.2019.07.37 article EN Journal of Thoracic Disease 2019-07-01

Ventilator-associated pneumonia (VAP) caused by drug-resistant Acinetobacter baumannii is associated with high mortality in critically ill patients. We identified the prognostic factors of 30-day patients VAP A. and compared survival outcomes among multidrug-resistant (MDR), extensively (XDR) pandrug-resistant (PDR) VAP.A retrospective cohort study was conducted Medical Intensive Care Unit at Chiang Mai University Hospital, Thailand. All adult diagnosed between 2005 2011 were eligible....

10.1186/s40560-015-0077-4 article EN cc-by Journal of Intensive Care 2015-03-01

Various vaccines have been developed to control the COVID-19 pandemic, but available were using ancestral SARS-CoV-2 wild-type (WT) strains. Commercial anti-SARS-CoV-2 receptor binding domain (RBD) antibody assays established and employed for validation of vaccine efficacy. However, these before variants concern (VOCs) emerged. It is unclear whether anti-RBD IgG levels can predict immunity against VOCs. In this study, we determined correlations between neutralizing antibodies (NAbs) in...

10.3390/diagnostics12061315 article EN cc-by Diagnostics 2022-05-25

(1) Background: Early identification of severe coronavirus disease 2019 (COVID-19) pneumonia at the initial phase hospitalization is very crucial. To address this, we validated and updated National Warning Score 2 (NEWS2) for this purpose. (2) Methods: We conducted a study on adult patients with COVID-19 infection in Chiang Mai, Thailand, between May 2021 October 2021. (3) Results: From total 725 patients, 350 (48.3%) suffered pneumonia. In determining pneumonia, NEWS2 + Age BMI (NEWS2 Plus)...

10.3390/jcm13010298 article EN Journal of Clinical Medicine 2024-01-04

Varenicline tartrate, a novel, selective, nicotinic acetylcholine receptor partial agonist, has been developed specifically as smoking cessation drug. This study evaluated the efficacy of standard regimen varenicline compared with placebo for in 333 subjects China, Singapore and Thailand.This 24-week, randomized, double-blind, placebo-controlled trial varenicline, 1 mg bd, consisted 12-week treatment period followed by non-treatment follow-up period. The primary end-point was 4-week...

10.1111/j.1440-1843.2008.01476.x article EN Respirology 2009-01-27

We conducted a retrospective cohort study in the medical intensive care unit of Chaing Mai University Hospital to describe epidemiology ventilator-associated pneumonia (VAP) and identify prognostic indicators 30-day VAP mortality. A total 621 patients diagnosed with between January 2005 December 2011 were included. The overall mortality rate was 44.4%. major causative pathogens Acinetobacter baumannii (54.3%), Pseudomonas aeruginosa (35.2%), methicillin-resistant Staphylococcus aureus...

10.7883/yoken.jjid.2014.282 article EN Japanese Journal of Infectious Diseases 2014-12-24

Radon exposure is the second leading cause of lung cancer, after smoking. In upper northern Thailand (UNT), cancer incidence was frequently reported by National Cancer Institute. Besides smoking, radon may also influence high in this region. Indoor concentrations were measured 192 houses eight provinces UNT. ranged from 11 to 405 Bq m-3 and estimated annual effective dose 0.44 12.18 mSv y-1. There significant differences indoor between cases healthy controls (p = 0.033). We that 26% deaths...

10.1038/s41598-022-09122-y article EN cc-by Scientific Reports 2022-03-25

Small airways play a major role in the pathogenesis and prognosis of chronic obstructive pulmonary disease (COPD) asthma. More data on small airway dysfunction (SAD) using spirometry impulse oscillometry (IOS) these populations are required. The objective this study was to compare two methods, IOS, for SAD detection its prevalence defined by IOS subjects with COPD asthma without fixed airflow obstruction (FAO).This is cross-sectional study.Spirometric parameters were compared across four...

10.3389/fmed.2023.1181188 article EN cc-by Frontiers in Medicine 2023-05-17

Information is limited regarding the role of impulse oscillometry (IOS) for detection preserved ratio impaired spirometry (PRISm). Therefore, we aimed to study diagnostic ability IOS in differentiating between PRISm and healthy subjects. This retrospective data collection was done at Lung Health Center, Faculty Medicine, Chiang Mai University, Thailand July 2019 April 2022. The potential possibilities difference resistance 5 Hz (R5) 20 (R20) (R5-R20) were analyzed. prevalence higher when...

10.3390/arm93010002 article EN cc-by Advances in respiratory medicine 2025-01-27

Background/Objectives: Inhaled corticosteroids (ICS) affect oxidative stress and systemic inflammation, which might modify the risk of thrombosis in asthmatic patients exposed to particulate matter with an aerodynamic diameter smaller than 2.5 microns (PM2.5). Therefore, we aim know biomarkers stress, coagulation ICS-treated, well-controlled adult after exposure PM2.5. Methods: This study was conducted compare urinary i.e., 8-hydroxydeoxyguanosine (8-OHdG), blood inflammation...

10.3390/jcm14072360 article EN Journal of Clinical Medicine 2025-03-29

Seasonal smog produces particulate matters that are less than 10 microns in diameter (PM₁₀), which known to have several impacts on the respiratory system.This study was determine association of an increased PM10 level due seasonal Chiang Mai and emergency visits for asthma chronic obstructive pulmonary disease (COPD) exacerbations.A retrospective cross-sectional conducted between months January March from 2006 until 2009. The PM₁₀ daily number COPD exacerbations were analyzed using a...

10.12932/ap0668 article EN Asian Pacific Journal of Allergy and Immunology 2016-01-01

Asia-Pacific Burden of Respiratory Diseases (APBORD) was a cross-sectional, observational study examining the burden respiratory disease in adults across 6 countries. This article reports symptoms, healthcare resource utilization (HCRU), work impairment and cost associated with allergic rhinitis (AR), asthma, chronic obstructive pulmonary (COPD), rhinosinusitis Thailand. Consecutive participants aged ≥18 years primary diagnosis AR, COPD, or were enrolled at 4 hospitals Thailand during...

10.1097/md.0000000000004090 article EN cc-by-nc Medicine 2016-07-01

The impact of outdoor air pollution on the quality life (QoL) chronic obstructive pulmonary disease (COPD) patients, as measured by COPD assessment test (CAT) questionnaire, is limited. aim this study was to determine a short-term increase in particulate matter which particles are less than 10 microns diameter (PM10) during seasonal smog period QoL, symptoms, and lung function patients. This prospective observational conducted at Chiang Dao Hospital, Mai, Thailand between March August 2016....

10.3390/ijerph16010106 article EN International Journal of Environmental Research and Public Health 2019-01-02

Open burnings, agricultural and forest fires, are the major sources of particulate matters (PM) in Chiang Mai during dry season. We aim to determine association an increased daily PM (PM10, PM2.5) non-accidental mortality causes death Mai. The between including were analyzed using a generalized linear model with Poisson distribution. results showed that PM10 PM2.5 associated on different lag days (adjusted RR range from 1.009–1.018 1.016 for each 10 µg/m3 increment PM2.5, respectively)....

10.1080/09603123.2019.1673883 article EN International Journal of Environmental Health Research 2019-10-01

Abstract Background Glyphosate is a herbicide which commonly used in agricultural areas. However, previous studies on glyphosate exposure farmers and their health are still scarce. Methods A longitudinal pre-post study was performed among maize farmers. Information from questionnaires, urine blood samples, lung function were collected day before after application the morning. The samples analyzed using liquid chromatography-tandem mass spectrometry to detect levels. Serum malondialdehyde...

10.1186/s12889-022-13696-7 article EN cc-by BMC Public Health 2022-07-14

Background: The sequelae of post-coronavirus disease 2019 (COVID-19) have been widely reported. However, the time point follow-up in previous studies varied ranging from 3–24 months and interval was too long (6 or 12 months). Thus, a shorter during recovery for assessment post COVID-19 on lung function exercise capacity is still required. Therefore, this study aims to explore long-term impact pneumonia pulmonary capacity.

10.21037/jtd-23-514 article EN Journal of Thoracic Disease 2023-09-01

The aim of the study was to determine whether asthma management in Thailand is succeeding achieving levels control, specified national and international guidelines.Adults with Bangkok, Chiang Mai, Songkhla, Khon Kaen were interviewed, we have reported on their severity, morbidity, perception asthma, healthcare use.A total 466 sufferers interviewed. burden high, 14.8% respondents being hospitalized for past year. One-quarter those surveyed had lost workdays as a result most patients felt that...

10.1111/j.1440-1843.2004.00584.x article EN Respirology 2004-08-01
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