- Adipose Tissue and Metabolism
- Mitochondrial Function and Pathology
- Cardiac Ischemia and Reperfusion
- Diet and metabolism studies
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Biochemical effects in animals
- Neuroinflammation and Neurodegeneration Mechanisms
- Cardiac electrophysiology and arrhythmias
- Chemotherapy-induced cardiotoxicity and mitigation
- Cancer-related cognitive impairment studies
- Gut microbiota and health
- Heart Rate Variability and Autonomic Control
- Cardiovascular Function and Risk Factors
- Neurological Disease Mechanisms and Treatments
- Trace Elements in Health
- Vagus Nerve Stimulation Research
- Regulation of Appetite and Obesity
- Metabolism, Diabetes, and Cancer
- Alzheimer's disease research and treatments
- Stress Responses and Cortisol
- Antioxidants, Aging, Portulaca oleracea
- Ion channel regulation and function
- Diabetes Treatment and Management
- Neuropeptides and Animal Physiology
Chiang Mai University
2016-2025
Thailand Center of Excellence in Physics
2012-2023
Kanazawa University
2017
University of Dundee
2016-2017
NYU Langone Health
2016-2017
Centre National de la Recherche Scientifique
2016
Centre de Recherches sur la Cognition Animale
2016
Faculty (United Kingdom)
2012-2013
University of Alabama at Birmingham
2002-2003
University of North Carolina at Chapel Hill
1999
Recent evidence has demonstrated that insulin resistance is related to the development of type 2 diabetes mellitus. Our previous study found high-fat diet (HFD) consumption caused not only peripheral and brain but also mitochondrial dysfunction cognitive impairment. Vildagliptin sitagliptin, dipeptidyl-peptidase-4 inhibitors, are recently developed anti-diabetic drugs. However, effects both drugs on behaviors function in HFD-induced insulin-resistant rats have yet been investigated. Sixty...
Epidemiological studies indicate that insulin resistance (IR), a hallmark of type 2 diabetes, is associated with an increased risk major depression. Here, we demonstrated male mice fed high-fat diet (HFD) exhibited peripheral metabolic impairments reminiscent IR accompanied by elevated circulating levels branched-chain amino acids (BCAAs), whereas both parameters were normalized chronic treatment metformin (Met). Given the role BCAAs in regulation tryptophan influx into brain, then explored...
Traumatic brain injury (TBI) is associated with an increased risk of cognitive, psychiatric, and neurodegenerative complications that may develop after injury. Increased microglial reactivity following TBI underlie chronic neuroinflammation, neuropathology, exaggerated responses to immune challenges. Therefore, the goal this study was force turnover trauma-associated microglia diffuse determine whether alleviated inflammation, improved functional recovery attenuated reduced...