- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Colorectal Cancer Screening and Detection
- Esophageal Cancer Research and Treatment
- Gastrointestinal disorders and treatments
- Respiratory viral infections research
- Chronic Myeloid Leukemia Treatments
- Hemoglobinopathies and Related Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Colorectal Cancer Surgical Treatments
- Pancreatitis Pathology and Treatment
- Abdominal Surgery and Complications
- Pneumothorax, Barotrauma, Emphysema
- Tracheal and airway disorders
- Chronic Lymphocytic Leukemia Research
- Gallbladder and Bile Duct Disorders
- Blood groups and transfusion
- Helicobacter pylori-related gastroenterology studies
- SARS-CoV-2 detection and testing
- Antimicrobial Peptides and Activities
- Trauma and Emergency Care Studies
Aga Khan University
2022-2025
University of Pavol Jozef Šafárik
2024-2025
Omdurman Islamic University
2025
University of Pennsylvania
2024
Riyadh Armed Forces Hospital
2024
University of Gezira
2024
Al-Neelain University
2024
University of Khartoum
2024
National Center for Cancer Care and Research
2020-2023
Hamad Medical Corporation
2016-2023
Abstract CONTEXT: Cardiovascular–kidney–metabolic (CKM) syndrome is a complex condition arising from interrelated factors such as heart disease, diabetes mellitus (DM), kidney dysfunction, and obesity. These may cause multiple organ failure, thus impacting patient’s health. AIMS: The aim of this study was to explore the association between CKM risk factors, estimated glomerular filtration rate, blood pressure, albumin-creatinine ratio, age, body mass index (BMI), low-density lipoprotein...
Abstract Objectives To estimate prevalence rates and identify baseline predictors of adverse events (AEs) over the first year treatment in patients with RA starting MTX. Methods Data came from UK Rheumatoid Arthritis Medication Study (RAMS), a prospective cohort This analysis included aged ≥18 years physician diagnosed symptom duration ≤2 years, who were commencing MTX for time. AEs recorded by interviewing at 6- 12-month follow-up visits. The period are reported 0–6 months, 6–12 months 0–12...
Albinism is an autosomal recessive disorder characterized by the absence of melanin in skin, albinism has a prevalence 1 1000 sub-Saharan Africa, with lack increased risk skin malignancy. Trichlemmal carcinoma rare malignant adnexal tumor mostly sun-exposed areas. We are presenting case 35-year-old albino patient previous history squamous cell full recovery. Presented bilateral axillary masses no other finding or examination. Short period deference between two tumors rapidly growing course....
Introduction A subset of COVID-19 disease patients suffers a severe form the illness; however, underlying early pathophysiological mechanisms associated with remain to be fully understood. Several studies showed association severity changes in expression profile various matrix metalloproteinases (MMPs) and defensins (DA). However, link between MMPs DA nasopharyngeal milieu during phases infection remains poorly Therefore, we performed differential gene analysis swab samples collected from...
SARS-CoV-2 infection can present with various clinical features, among which gastrointestinal manifestations such as nausea, diarrhea, vomiting, and mild abdominal pain have been reported. Recognition of rare presentations has increased over time. These atypical may lead to difficulties in establishing the diagnosis a timely manner; furthermore, they unnecessary investigations, extended hospital stays, adverse outcomes, more strain on healthcare resources. We three cases admitted our picture...
As the cases of COVID-19 are flooding around world, atypical presentations being recognized, making diagnosis challenging. Gastrointestinal symptoms and mild abdominal pain common. However, severe associated with warranting surgical evaluation has been rarely described; recognizing such differentiating them from a abdomen is critical to effectively safely manage patients. Here we present case middle-aged gentleman who developed features resembling secondary peritonitis. Eventually, he was...
Expression and certain SNPs of interferon lambda 3 4 (IFNL3 4) have been associated with variable outcomes in COVID-19 patients different regions, suggesting population-specific differences the disease outcome. This study examined association INFL3 INFL4 (rs12979860 rs368234815, respectively) nasopharyngeal expression severity Pakistani patients.For this study, 117 retrospectively collected swab samples were used from individuals mild severe disease. qPCR assays to determine viral loads mRNA...
Hereditary blood diseases are widespread among the Arab population due to high rates of consanguineous marriages; research regarding perception marriage in some countries, such as Qatar, is extremely scarce. Therefore, this study aimed investigate prevalence and assess Qatari population.A cross-sectional used a self-administered questionnaire 395 adults aged 18-35 who attended primary healthcare institutions Qatar. A convenience sampling technique was select participants. An independent...
Abstract Introduction A subset of COVID-19 disease patients suffers a severe form the illness, however, underlying early pathophysiological mechanisms associated with remain to be fully understood. Several studies showed association severity changes in expression profile various matrix metalloproteinases (MMPs) and defensins. However, link between metalloproteinase defensins (DA) nasopharyngeal milieu, during phases infection, remains poorly Therefore, we performed differential gene analysis...
Abstract Patients with type 1 diabetes (T1D) who are obese at risk of cardiovascular disease, renal diseases, and other complications. Unfortunately, there is currently no cure for T1D, necessitating individuals this condition to rely on lifelong insulin therapy. Tirzepatide, a dual-acting glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 agonist, has recently been approved treating 2 diabetes. We report the case 38-year-old male presented stage chronic kidney obesity,...
Background Thorough and standardized documentation of operative notes is essential for effective communication, patient safety, legal protection, the continuity care. However, in many hospitals Sudan, surgeons often use non-standardized methods, resulting inconsistent incomplete records. This study evaluates quality at Port Sudan Teaching Hospital using Royal College Surgeons England (RCSEng) guidelines, aiming to improve compliance practices. Methods A clinical audit was conducted two...
Background and aims Coronavirus disease 2019 (COVID-19) is caused by a virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the first pandemic wave, SARS-CoV-2 had developed significant changes mutations that resulted in emergence of different strains. Each strain varies its virulence severity. Most reports have shown Omicron variant causes mild illness. Little about impact patients with chronic myeloid leukemia. We present leukemia who infection their outcomes....
Sickle cell disease (SCD) is one of the most common hematological diseases, which results in variable complications. The treatment SCD evolving but limited options are available for now. Acute chest syndrome (ACS) serious complications observed and a challenging prevention. Crizanlizumab monoclonal antibody that binds to P-selectin improves blood flow by preventing sickle adhesion endothelium, resulting improvement vaso-oclusive crises (VOC). It not well evaluated terms ACS Here we report...
Jejunoileal diverticulosis (JID) is a rare and nonspecific symptomatic disease. It usually an acquired condition associated with false diverticula integrated colonic which can be diagnosed incidentally or later complications. A sixty-nine-year-old male presented sudden onset generalized abdominal pain. Computed tomography (CT) imaging was suggestive of ileal diverticulitis localized perforation. The patient treated conservatively IV fluids antibiotics kept nil per orem for three days...
Acute pancreatitis can result secondary to an inflammatory cascade due insult the pancreatic parenchyma, whether it be from infections, medications, etc. We present a case of 37-year-old male with acute after being started on Paxlovid, combination drug containing Nirmatrelvir and Ritonavir, for COVID-19 treatment. Multiple reports in literature have documented such association between protease inhibitor Ritonavir. suspect that similar results may taken place link initiation this medication...
The endoscopic Functional Lumen Imaging Probe (FLIP) devices are used to evaluate pressure changes, diameter, and volume of the esophagus. We FDA’s MAUDE database collect post-marketing surveillance data on these from January 2009 September 2022. Forty-Five device-related events thirty-six patient-related adverse were analyzed. most common device issue for diagnostic FLIP was therapeutic/diagnostic failure (n = 6), while frequent with therapeutic without an identified or use problem 11)....