A5064829420- Peripheral Neuropathies and Disorders
- Heart Rate Variability and Autonomic Control
- Hereditary Neurological Disorders
- Cardiovascular Syncope and Autonomic Disorders
- Autoimmune Neurological Disorders and Treatments
- Genetic Neurodegenerative Diseases
- Peripheral Nerve Disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Neuroscience of respiration and sleep
- Pain Mechanisms and Treatments
- Long-Term Effects of COVID-19
- Myasthenia Gravis and Thymoma
- Vagus Nerve Stimulation Research
- Botulinum Toxin and Related Neurological Disorders
- Neurological and metabolic disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Sleep and Wakefulness Research
- Advanced Neuroimaging Techniques and Applications
- Ophthalmology and Eye Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Sympathectomy and Hyperhidrosis Treatments
- Pain Management and Treatment
- Orthopedic Surgery and Rehabilitation
- Cancer, Stress, Anesthesia, and Immune Response
- Congenital limb and hand anomalies
Mayo Clinic
2020-2025
WinnMed
2020-2025
Mayo Clinic in Arizona
2019-2024
Neurology, Inc
2022
University of Tasmania
2021
Menzies School of Health Research
2021
Cleveland Clinic
2018-2019
Wayne State University
2018-2019
Detroit Medical Center
2018
Post-COVID-19 syndrome is a poorly understood aspect of the current pandemic, with clinical features that overlap symptoms autonomic/small fiber dysfunction. An early systematic analysis autonomic dysfunction following COVID-19 lacking and may provide initial insights into spectrum this condition. We conducted retrospective review all patients confirmed history infection referred for testing concerning para-/postinfectious at Mayo Clinic Rochester or Jacksonville between March 2020 January...
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is difficult to distinguish from mimicking disorders, with misdiagnosis resulting in IVIG overutilization. We evaluate a clinical-electrophysiological model facilitate CIDP versus mimic neuropathy prediction. Using the European Academy of Neurology/Peripheral Nerve Society (EAN/PNS) 2021 guidelines we derived 26 clinical and 144 nerve conduction variables. The was generated validated utilizing total (n = 129) mimics 309);...
ABSTRACT Background and Aims Nerve conduction studies (NCS) are integral to diagnosing chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), but their role in predicting treatment outcomes remains underexplored. This study evaluates NCS changes at first follow‐up (first changes) as predictors of success CIDP, focusing on correlation with clinical over time. Methods Newly diagnosed CIDP patients meeting the 2021 EAN/PNS criteria were retrospectively evaluated. Baseline parameters...
There are limited population-based data on small fiber neuropathy (SFN). We wished to determine SFN incidence, prevalence, comorbid conditions, longitudinal impairments, and disabilities.Test-confirmed patients with in Olmsted, Minnesota, adjacent counties were compared 3:1 matched controls (January 1, 1998-December 31, 2017).Ninety-four identified, an incidence of 1.3/100,000/y that increased over the study period a prevalence 13.3 per 100,000. Average follow-up was 6.1 years (0.7-43...
Sensory loss with normal nerve conduction studies (NCS) from focal sensory root inflammatory demyelination is characteristic of chronic immune polyradiculopathy (CISP). However, nonpure cases involving motor and distal nerves exist (CISP-plus). We hypothesize that CISP-plus CISP are fundamentally part the same syndrome through comparison clinical, neurophysiologic, pathologic features.CISP-plus (primary dorsal lesser involvement) were retrospectively analyzed (1986-2019).We identified 44 28...
Vasculitic neuropathy is caused by inflammatory destruction of nerve blood vessels resulting in ischemia. Nerve vasculitis can be divided into two categories based on vessel size - large arteriole (≥75 µm) and microvasculitis (<75 µm). Herein, we characterize the clinical features large-arteriole compared to microvasculitis. This a retrospective cohort study patients evaluated biopsied at Mayo sites between 2001 2020. We collected histopathological data from whose biopsies were either...
To longitudinally investigate patients with multifocal acquired demyelinating sensory and motor neuropathy (MADSAM), quantifying timing location of involvements in onset patients, along clinicohistopathologic electrophysiologic findings to ascertain differences without monoclonal gammopathy uncertain significance (MGUS).Patients MADSAM seen at Mayo Clinic tested for ganglioside antibodies were retrospectively reviewed (January 1, 2007-December 31, 2018).Of 76 MADSAM, 53% had pure motor, 16%...
Abstract Introduction/Aims Recently, our group found an association between diabetes mellitus (DM) and lumbosacral radiculoplexus neuropathy (LRPN) in Olmsted County, Minnesota; we a higher risk (odds ratio [OR], 7.91) for developing LRPN diabetic compared with nondiabetic patients. However, the influence of other comorbidities anthropomorphic variables was not studied. Methods Demographic clinical data from 59 patients 177 age/sex‐matched controls were extracted using Rochester...
The sympathetic nervous system has a critical role in maintenance of arterial blood pressure; regulation regional flow; thermoregulation; and integrated response to exercise, disturbances homeostasis, external stressors. Together with the parasympathetic system, output participates control pupillary, gastrointestinal, bladder, sexual organ function. preganglionic neurons (SPNs) form distinct functional subunits that initiate patterns responses via their excitatory inputs ganglion or adrenal...
Carpal and cubital tunnel syndrome (CTS, CuTS) are common among patients with hereditary neuropathy liability to pressure-palsies (HNPP) Charcot-Marie-Tooth type 1A (CMT1A) may impact quality of life. We aimed evaluate the utility nerve decompression surgeries in these patients.Medical records were reviewed for PMP22 mutations confirmed Mayo Clinic laboratories from January 1999 December 2020, who had CTS CuTS underwent surgical decompression.CTS occurred 53.3% HNPP 11.5% CMT1A, while was...