- Sports injuries and prevention
- Cardiovascular Effects of Exercise
- Shoulder Injury and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Injury Epidemiology and Prevention
- Lower Extremity Biomechanics and Pathologies
- Musicology and Musical Analysis
- Mitochondrial Function and Pathology
- Traumatic Brain Injury Research
- Streptococcal Infections and Treatments
- Occupational Health and Performance
- Muscle and Compartmental Disorders
- Neurofibromatosis and Schwannoma Cases
- Ubiquitin and proteasome pathways
- Thermoregulation and physiological responses
- Sports Performance and Training
- Respiratory viral infections research
- Exercise and Physiological Responses
- Immune Cell Function and Interaction
- Sports and Physical Education Research
- Occupational exposure and asthma
- Autopsy Techniques and Outcomes
- Cardiac Arrest and Resuscitation
- Sport Psychology and Performance
- Trauma Management and Diagnosis
Arizona State University
2023
Jersey Shore University Medical Center
2000-2021
Rutgers, The State University of New Jersey
2006-2021
University of Central Lancashire
2018
Barrow Neurological Institute
2007-2016
Newcastle upon Tyne Hospitals NHS Foundation Trust
2016
Royal Victoria Infirmary
2015-2016
Phoenix Children's Hospital
2016
Prince Philip Hospital
2013
St. Joseph's Hospital and Medical Center
2007-2011
To determine the incidence of lower-extremity injury among high school cross-country runners and to identify risk factors for injury, authors prospectively monitored a cohort 421 competing on 23 teams in 12 Seattle, Washington, schools during 1996 season. Collected were daily athletic exposure (AE) reports, baseline questionnaire prior running experience, anthropometric measurements, coaches' training logs. The overall rate was 17.0/1,000 AEs. Girls had significantly higher (19.6/1,000 AEs)...
A proper heat-acclimatization plan in secondary school athletic programs is essential to minimize the risk of exertional heat illness during preseason practice period. Gradually increasing athletes' exposure duration and intensity physical activity environment minimizes heat-illness while improving performance. Progressive acclimatization especially important initial 3 5 days summer practices. When an athlete undergoes a program, physiologic function, exercise tolerance, performance are all...
Objective To determine the incidence rate of injury among high school cross country runners over a 15-year period. Design Prospective–longitudinal. Setting Twenty-three schools in western Washington State under surveillance University Athletic Health Care System between 1979–1994. Participants One hundred and ninety-nine teams. Main Outcome Measure Injuries resulting from running practice or meet. Results There were 1,622 injuries for an overall 13.1/1,000 athletic exposures (AEs), i.e.,...
Abstract Background Rett syndrome (RTT), a common cause of mental retardation in girls, is associated with mutations the MECP2 gene. Most human cases mutation girls result classical or variant forms RTT. When these same occur males, they often present as severe neonatal encephalopathy. However, some can also lead to diseases characterized syndromes, particularly boys. One mutations, A140V, common, recurring missense accounting for about 0.6% all MeCP2 and ranking 21 st by frequency. It has...
This Policy Statement was reaffirmed November 2019. Results of new research indicate that, contrary to previous thinking, youth do not have less effective thermoregulatory ability, insufficient cardiovascular capacity, or lower physical exertion tolerance compared with adults during exercise in the heat when adequate hydration is maintained. Accordingly, besides poor status, primary determinants reduced performance and exertional heat-illness risk sports other activities a hot environment...
Exposure to metal working fluid (MWF) has been associated with outbreaks of extrinsic allergic alveolitis (EAA) in the USA, bacterial contamination MWF being a possible cause, but is uncommon UK. Twelve workers developed EAA car engine manufacturing plant UK, presenting clinically between December 2003 and May 2004. This paper reports subsequent epidemiological investigation whole workforce. The study had three aims: (1) measure extent outbreak by identifying other who may have or...
Design Prospective cohort study. Objectives To determine the relationship between quadriceps angle (Q-angle) and risk of lower extremity injury among adolescent cross-country runners. Background No consensus exists on role Q-angle as a factor for lower-extremity overuse injury, especially effect large or right-left difference. Methods Measures The Q-angles 393 high school runners, 13 to 19 years age, were goniometrically measured in static, standing position with relaxed. runners followed...
Abstract Background Tuberous sclerosis complex (TSC) is an autosomal dominant neurogenetic disorder caused by mutations in one of two genes, TSC1 or TSC2 , which encode the proteins hamartin and tuberin, respectively [1–3]. Common features TSC include intractable epilepsy, mental retardation, autistic features. associated with specific brain lesions, including cortical tubers, subependymal nodules giant cell astrocytomas. In addition, this disease frequently produces characteristic tumors,...
Participation in organized sports has a variety of health benefits but also the potential to expose athlete infectious diseases, some which may produce outbreaks. Major risk factors for infection include skin-to-skin contact with athletes who have active skin infections, environmental exposures and physical trauma, sharing equipment contaminated fomites. Close that is intrinsic team psychosocial associated adolescence are additional risks. Minimizing requires leadership by community...
This article describes how two self-advocates worked with academics and others to produce a toolkit help self-advocacy groups run better projects. We begin by explaining why this research needed doing we carried out the research. then talk about what co-produced means us think it is different from participatory or inclusive discuss whether were co-produced. finish looking at co-production added value Our aim activists work together achieve things: good-quality findings; big differences...
Neurofibromatosis type 1 is an autosomal dominant disorder characterized by neurocutaneous abnormalities, learning disabilities, and attention-deficit disorder. symptom severity can be highly variable even within families where all affected members carry the same mutation. We hypothesized that variation in expression of normal NF1 allele may a mechanism participates producing phenotypes. performed allelic imbalance assays on healthy control individuals to estimate prevalence skewed gene....
From Pediatric Sports Medicine Fellowship Program, Jersey Shore University Medical Center, Neptune, and Department of Pediatrics, Dentistry New Jersey—Robert Wood Johnson School, Piscataway, (Dr Rice); Fellow in Medicine, Waniewski). Received for publication July 2003; accepted 2003. This statement was unanimously approved at the IMMDA General Assembly, Fall 2001. article editorially prepared by an committee Drs. Steve Van Camp, MD, FACSM (Chair), Lewis G. Maharam, FACSM; Pedro Pujol, Jan...
The lipolytic enzyme hepatic lipase (HL) may facilitate mobilization of cholesterol substrate for ovarian steroidogenesis. We investigated whether HL was necessary optimum reproduction in the female mouse by analyzing breeding performance and responses to gonadotropins HL−/− mice. mice bred with males had same pregnancy success rate pup survival as did wild-type (WT) but significantly smaller litters, producing 1.7 fewer pups per litter. Mice were primed eCG/hCG, at 6 h post-hCG ovaries than...
The neuropathological consequences of Gamma Knife radiosurgery (GK) on hypothalamic hamartoma (HH) are unknown.In a cohort patients undergoing surgery for treatment-resistant epilepsy, we compared surgically resected HH tissue from without (group I; n = 19) and with II; 10) history GK (median dose 16 Gy to the 50% isodose margin).Techniques included thick-section stereology total nucleated neuron cell counts, thin-section immunohistochemistry. Normal human hypothalamus derived age-matched...
The concept of quality life (QOL) is multidimensional and complex, especially in regard to chronic disease old age. purpose this study was explore QOL a population elderly patients with hypertension suggest technique for model building. specific the test viability understanding how treatment affects QOL. Indicators determinants were measured group aged 60 years or older hypertension. Correlation coefficients confirmed hypothesized model. thus can be used other diseases assess effects diseases.
The 'cholinergic hypothesis', based on the correlation of reduction cholinergic activity in Alzheimer's disease (AD) with cognition and memory, is currently most widely-held view for AD. Drug treatments AD focus mainly inhibition
Mutations of the SACS gene have been reported in patients with autosomal recessive spastic ataxia Charlevoix-Saguenay from Canada (Quebec), Tunisia, Japan, Turkey, Belgium, Italy, Spain, Netherlands, and Germany. Features that distinguish other ataxias include sensory motor polyneuropathy hypermyelinated retinal nerve fibers. We describe clinical, electrophysiological, radiological features 2 white American siblings diagnosed Charlevoix-Saguenay. The affected children are compound...