A5076994948- Pesticide Exposure and Toxicity
- Birth, Development, and Health
- Carcinogens and Genotoxicity Assessment
- Gestational Diabetes Research and Management
- Air Quality and Health Impacts
- Pregnancy and preeclampsia studies
- Pesticide and Herbicide Environmental Studies
- Insect and Pesticide Research
- Maternal Mental Health During Pregnancy and Postpartum
- Effects and risks of endocrine disrupting chemicals
- Heavy Metal Exposure and Toxicity
- Pregnancy and Medication Impact
- Asthma and respiratory diseases
- Indoor Air Quality and Microbial Exposure
- Child Nutrition and Feeding Issues
- Toxic Organic Pollutants Impact
- Pesticide Residue Analysis and Safety
- Obesity, Physical Activity, Diet
- Occupational exposure and asthma
- Contact Dermatitis and Allergies
- Neonatal Respiratory Health Research
- Occupational and environmental lung diseases
- Peroxisome Proliferator-Activated Receptors
- Maternal and Perinatal Health Interventions
- Environmental Toxicology and Ecotoxicology
Nagoya City University
2016-2025
Mizuho (Japan)
2012-2024
Hyogo University
2024
Kumamoto University
2024
National Institute for Environmental Studies
2020-2023
Nagoya University
2003-2019
The University of Kitakyushu
2010
Yamato University
2010
University of California, Berkeley
1998-2000
Aichi Gakuin University
1998
<h3>Importance</h3> It is unclear to what extent the duration of screen time in infancy associated with subsequent diagnosis autism spectrum disorder. <h3>Objective</h3> To examine association between and development disorder at 3 years age. <h3>Design, Setting, Participants</h3> This cohort study analyzed data from mother-child dyads a large birth Japan. included children born women recruited January 2011 March 2014, were December 2020. The was conducted by Japan Environment Children's...
Over the last two decades, usage of neonicotinoid (NEO) insecticides has increased due to their high selectivity for insects versus mammals and effectiveness extermination resistant conventional pesticides such as pyrethroids organophosphates (OPs). However, historical change NEO exposure level in humans is poorly understood. The aim this study reveal changes levels OP human body over decades using biomonitoring technique. We quantified urinary concentrations 7 NEOs (acetamiprid,...
Capturing epidemiological signatures is essential to document burdens of disease and design health care services, including prevention measures, clinical interventions, policies. There are large geographical ethnic variations in the epidemiology allergic immunological diseases. Various data available from North America Europe, but diseases Asia not well documented.
Di(2-ethylhexyl)phthalate (DEHP), a commonly used industrial plasticizer, causes liver tumorigenesis presumably via activation of peroxisome proliferator-activated receptor alpha (PPARalpha). The mechanism DEHP has not been fully elucidated, and to clarify whether is induced PPARalpha, we compared DEHP-induced in wild-type Pparalpha-null mice. Mice each genotype were divided into three groups, treated for 22 months with diets containing 0, 0.01 or 0.05% DEHP. Surprisingly, the incidence...
Permethrin, a popular synthetic pyrethroid insecticide used to control noxious insects in agriculture, forestry, households, horticulture, and public health throughout the world, poses risks of environmental exposure. Here we evaluate reproductive toxicity cis-permethrin adult male ICR mice that were orally administered (0, 35, or 70 mg/kg d) for 6 wk. Caudal epididymal sperm count motility treated groups statistically reduced dose-dependent manner. Testicular testosterone production plasma...
Indoor air concentrations of volatile organic compounds (VOCs), carbon monoxide (CO), dioxide (CO2), nitrogen (NO2), and dust particles were measured for 49 biomass 46 fossil fuel users in urban slums Dhaka, Bangladesh. The health impacts these pollutants assessed on 65 51 children under five years old from families who use as main source energy, respectively. Mean CO found to be significantly higher (P = 0.010), while geometric mean benzene, xylene, toluene, hexane, total VOCs, NO2 < 0.01)...
Significant amounts of pyrethroid pesticides are used throughout China. Previous studies have suggested that exposure to may increase the risk childhood cancer; however, few focused on metabolites. We investigated five nonspecific metabolites found in children's urine and examined correlation with leukemia. conducted a hospital-based case-control study acute lymphocytic leukemia (ALL) Shanghai between 2010 2011. The included 176 children aged 0-14 years 180 controls matched for age sex....
Biological Monitoring Method for Urinary Neonicotinoid Insecticides Using LC‐MS/MS and Its Application to Japanese Adults: Jun UEYAMA, et al . Department of Pathophysiological Laboratory Sciences, Field Radiological Medical Nagoya University Graduate School Medicine— Objectives Agricultural use neonicotinoid (NEO) insecticides has been increasing in recent years, but their biological monitoring methods have scarcely reported. In this study, we developed validated a rapid sensitive method...
The Japan Environment and Children's Study (JECS) is a nationwide birth cohort study investigating environmental effects on children's health development. A Sub-Cohort has begun, conducting extended exposure outcome measurements by targeting subgroup randomly selected from the JECS Main Study. We report methodology participants' baseline profiles.Of 100,148 children in Study, born after April 1, 2013 who met eligibility criteria ([1] all questionnaire medical record data their mothers...
This research aimed to examine the efficacy of early initiation breastfeeding within 1 h birth, skin-to-skin contact, and rooming-in for continuation exclusive until 6 months postpartum. The used data from Japan Environment Children's Study (JECS), a nationwide government-funded birth cohort study. A total 80,491 mothers in between January 2011 March 2014 who succeeded or failed exclusively breastfeed were surveyed JECS. Multiple logistic regression model was analyse data. percentage is...
Prenatal cadmium exposure has been associated with adverse neurodevelopmental outcomes. However, previous findings are contradictory, and little is known about the potential modifiers of cadmium-related risk. We investigated associations between prenatal neurodevelopment in 2-year-old children examined influence mother/child characteristics. recruited 3545 mother–child pairs from Japan Environment Children's Study. collected maternal blood during mid/late pregnancy cord at delivery, measured...
The extremes of maternal pre-pregnancy body mass index (BMI) are known to be risk factors associated with obstetric and adverse perinatal outcomes. Among Japanese women aged 20 years or older, the prevalence underweight (BMI < 18.5 kg/m2) was 11.5% in 2019. Maternal thinness is a health problem caused by desire become slim. This study aimed investigate association between severity low BMI outcomes, including preterm birth (PTB), weight (LBW), small-for-gestational age (SGA).We conducted...
It is unclear whether increased television (TV) and DVD viewing in early childhood from age 1 year decreases development or poor increases TV/DVD viewing.
Abstract The association between maternal pre-pregnancy smoking status and asthma risk is unclear. This study aimed to investigate the pre- post-pregnancy bronchial at 3 years of age in a large birth cohort. Data 75,411 mother–child pairs from Japan Environment Children's Study (JECS) were analysed using multivariate logistic regression analysis. Overall, 7.2% children had asthma. before childbirth was as follows: Never = 60.0%, Quit recognising current pregnancy 24.1%, after finding out...
To investigate the prevalence and risk factors of epicondylitis among cooks in nursery schools a cross sectional study because they are suspected to have strenuous workloads on hands arms.Prevalence 209 school 366 control workers aged 40-59 were studied. Both groups consisted women chosen from 1299 subjects who agreed participate 1329 social welfare employees city. All interviewed with questionnaire had clinical examination tenderness palpation epicondyles epicondylar pain provoked by...
This study aims at clarifying the semen indices of insecticide sprayers who are exposed mainly to organophosphorus and pyrethroid insecticides. Eighteen male out 54 working for 9 companies in central Japan 18 age-matched students or medical doctors as unexposed controls participated detailed reproductive check-ups conducted summer following winter. The were insecticides more summer, busiest season, than winter, off-season (p<0.05). Erythrocyte true cholinesterase activities lower (p<0.05),...
This study assessed subjective symptoms related to indoor concentrations of chemicals among residents in a housing estate Dalian, China, where air pollution by interior decoration materials has recently become major health problem. Fifty-nine males and 50 females were surveyed for their sick building syndrome. Formaldehyde (HCHO), NO2, volatile organic compounds (VOCs) dwellings collected using diffusion sampler measured GC/MS. For with one or more the past, HCHO, butanol 1,2-dichloroethane...