A5034014697- Chronic Kidney Disease and Diabetes
- Mycobacterium research and diagnosis
- Cancer-related molecular mechanisms research
- Dialysis and Renal Disease Management
- Circular RNAs in diseases
- Advanced X-ray and CT Imaging
- Gout, Hyperuricemia, Uric Acid
- Radiation Dose and Imaging
- MicroRNA in disease regulation
- Infectious Diseases and Tuberculosis
- Management of metastatic bone disease
- Diagnosis and treatment of tuberculosis
- Angiogenesis and VEGF in Cancer
- Renal cell carcinoma treatment
- Renal and Vascular Pathologies
- Bone Metabolism and Diseases
- RNA modifications and cancer
- Powdery Mildew Fungal Diseases
- Renal Diseases and Glomerulopathies
- Inflammatory Bowel Disease
- Pediatric health and respiratory diseases
- Phytochemicals and Antioxidant Activities
- Advanced Radiotherapy Techniques
- Thyroid Cancer Diagnosis and Treatment
- Bone health and osteoporosis research
Soochow University
2021-2025
Children's Hospital of Chongqing Medical University
2016-2025
Chongqing Medical University
2016
Henan Provincial Chest Hospital
2015
Kaifeng City Children's Hospital
2010
Beijing Xuanwu Traditional Chinese Medicine Hospital
2008
Capital Medical University
2008
Abstract Serum uric acid is an end‐product of purine metabolism. Uric concentrations in excess the physiological range may lead to diseases such as gout, cardiovascular disease, and kidney injury. The includes a variety cell types with specialized functions fluid electrolyte homeostasis, detoxification, endocrine functions. Two‐thirds excreted through kidney, however, exploration markers new therapeutic targets renal tissue hyperuricemia still lacking. Single‐cell spatial omics techniques...
Diabetic angiopathy, which includes diabetic kidney disease (DKD), cardio-cerebrovascular disease, and retinopathy (DR) among other diseases, is one of the most common complications affecting patients. Among these, DKD, a major cause morbidity mortality, affects about 40% Similarly, DR involves retinal neovascularization neurodegeneration as result chronic hyperglycemia main visual impairment blindness. In addition, inflammation also promotes atherosclerosis diabetes, with...
Clinicians have long been interested in understanding the molecular basis of diabetic kidney disease (DKD)and its potential treatment targets. Its pathophysiology involves protein phosphorylation, one most recognizable post-transcriptional modifications, that can take part many cellular functions and control different metabolic processes. In order to recognize changes DKD kidney, this study applied Tandem liquid chromatography-mass spectrometry (LC-MS/MS) Next-Generation Sequencing, along...
Diabetic nephropathy (DN) is the common cause of renal diseases such as end-stage disease (ESRD) and chronic kidney (CKD). Various diagnostic applications treatment methods are used for clinical but remain some prognosis issues. To avoid morbidity mortality related to DN, early detection complications well targeted therapeutic strategies essential. Considerable evidence indicates that non-coding RNA plays a vital role in biological processes various diseases, biomarkers targets. And most...
To establish a laboratory method for detection of Mycobacterium tuberculosis in sputum based on variable number tandem repeat (VNTR).Mycobacterium was tested by VNTR and fluorescent quantitative reverse transcription polymerase chain reaction (FQ-PCR) 130 samples from patients with pulmonary 200 specimens other lung diseases. According to the amplification conditions clinical needs, MTUB21, MUTB04, QUB18, QUB26, QUB11b, MIRU31, MIRU10 MIRU26 were selected as test targets. The results FQ-PCR...
Objective To assess the efficacy of combination Jiehe pellet and standardized anti-tuberculosis therapeutic regimen for pulmonary tuberculosis complicating cervical lymph node in aged. Methods A total 103 aged patients with were enrolled randomly allocated to either a group (control 51 patients) or plus (treatment 52 patients). The control treatment received 2HRZE/4HR 6 months, respectively. abscessed nodes treated by excision incision drainage after 4 weeks medicine both groups....
Objective To explore the effect of Feitai capsule combined with mycobacterium vaccae on immune function in elderly patients pulmonary tuberculosis. Methods A total 100 hospitalized from 2012 January to 2013 October Hebei Provincial Chest Hospital were randomly divided into 2 groups, 50 each group. The control group was treated conventional anti tuberculosis scheme (2HRZE/4HR); treatment additionally and intramuscular injection basis Both groups for 6 month after smear detection,...
Objective To study the expression of tumor suppressor gene TSHR and pl6 in papillary thyroid carcinoma (PTC) explore relationship tumorigenesis promoter aberrant methylation two above genes. Methods RT-PCR was used to detect mRNA genes 50 cases PTC, 20 nodular goiter 12 adenoma tissue. The status were detected by methylation-specific PCR technique (MSP) (which p16 nested PCR). hypermethylation tested randomly sequencing. Results Hypermethylation region from 68.0 % (34/50) 54.0 (27/50) while...
Objective To investigate and analyze the blood uric acid level detection rate of hyperuricemia (HUA) to discuss its related risk factors. Methods From January December 2016, physical biochemical examination were conducted a total 7 585 cases with health examination, which selected by using cluster sampling method. We analyzed in percentage factors HUA applying Pearson test Logistic regression. Results Detection this group was 32.76%, 32.88% males 32.69% females. The average...
Objective To study the changes of bone mineral density and metabolism index in patient with type 2 diabetes mellitus abnormal for providing evidence early screening mellitus. Methods A total 210 patients who were treated Shenzhen Hospital Peking University from January 2016 to June 2017 selected as subjects. According T value, divided into group (DOP group, 104 cases) without group(T2DM 106 cases). The compared between two groups. Results Compared T2DM femoral neck L2-L4 lumbar...