A5015657628- Antibiotic Resistance in Bacteria
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotic Use and Resistance
- Bacterial biofilms and quorum sensing
- Oral microbiology and periodontitis research
- Infective Endocarditis Diagnosis and Management
- Vibrio bacteria research studies
- Human Health and Disease
- Urinary Tract Infections Management
- Actinomycetales infections and treatment
- Chemical Synthesis and Analysis
- Antibiotics Pharmacokinetics and Efficacy
- Antimicrobial Peptides and Activities
- Dental Implant Techniques and Outcomes
- Bacterial Infections and Vaccines
- Tuberculosis Research and Epidemiology
- Bacterial Identification and Susceptibility Testing
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Dental Erosion and Treatment
- Yersinia bacterium, plague, ectoparasites research
- Otolaryngology and Infectious Diseases
- Healthcare Systems and Public Health
- Burkholderia infections and melioidosis
- Protease and Inhibitor Mechanisms
- Enterobacteriaceae and Cronobacter Research
University of Osijek
2017-2024
Klinički bolnički centar Osijek
2021-2023
Institute of Public Health Osijek-Baranja County
2015-2020
Resistance to carbapenems in Enterobacterales has become a matter of the highest concern last decade. Recently, harboring multiple carbapenemases were detected three hospital centers Croatia and outpatient setting, posing serious therapeutic challenge for clinicians. In this study, we analyzed eight Klebsiella pneumoniae two Enterobacter cloacae complex isolates with carbapenemases, regard antibiotic susceptibility, β-lactamase production plasmid content. The demonstrated uniform resistance...
A dramatic increase in OXA-48 β-lactamase was observed recently not only large hospital centres, but also smaller suburban centres geographic areas bordering Croatia. The aim of the study to analyse epidemiology, mechanisms antibiotic resistance and routes spread carbapenemase Croatia.Carbapenemase other fluoroquinolone genes were detected by PCR sequencing. Whole-genome sequencing (WGS) performed on five representative isolates. isolates genotyped PFGE.Forty-eight positive for OXA-48,...
Background: Gram-positive opportunistic bacteria of the Nocardia species are responsible for a large spectrum infections, such as pneumonia, skin and more widespread conditions, including brain abscesses. Case Description: A 67-year-old male patient suffered from headache, gait disorder, vertigo week before admission to our department. An enhanced magnetic resonance imaging scan revealed mediosagittal hyperintense infratentorial lesion with concomitant compression fourth ventricle. The...
The brucellosis and Q-fever coinfection is very rarely reported. To our knowledge, this the first case report of concomitant Q-fever, most likely imported in Croatia. A 30-year-old male agricultural worker was hospitalized on 22 April 2017 after a ten days fever up to 40°C with chills, shivering, excessive sweating, general weakness, loss appetite headache. month half prior hospitalization he lost 18 kg body weight. Three weeks before patient returned from Kupres (Bosnia Herzegovina) where...
The ability of A cinetobacter baumannii strains to form biofilm is one the most important virulence factor which enables bacterial survival in a harsh environment and decreases antibiotic concentration as well. Subminimal inhibitory concentrations (subMICs) antibiotics may change ultrastructure or have an influence on some different molecular mechanisms resulting morphological physiological changes bacteria itself. aim this study was determine effects 1/2, 1/4, 1/8 1/16 minimal...
<p><strong>Objective</strong>. The aim of this report was to describe the occurrence a bacterial brain abscess in healthy individual, without any predisposing condition. <strong>Case report</strong>. A thirteen-year old boy admitted Department Neurosurgery after onset vomiting, headache and dizziness. neurological deficit detected during physical examination so urgent magnetic resonance imaging performed, revealing an intrahemispheric, right positioned solitary...
An imipenem-resistant Bacteroides fragilis strain was isolated from the blood of a 72-year-old male patient with urinary bladder tumor in Osijek, Croatia. This also resistant to ampicillin, piperacillin/tazobactam, cefoxitin, clindamycin, tetracycline, and harbored cfiA, ermF , tetQ genes where high-level expression cfiA carbapenem-resistant gene driven by an IS 1187 element. Interestingly, despite feature B. blood, relatively easily recovered bacteremia. It first characterized isolate its...
The isolation of Candida may be related to comorbidity, prolonged mechanical ventilation, and survival during intensive care unit (ICU) stay, especially with non-albicans (NAC). To examine the frequency isolation, associated comorbidities outcomes in surgical ICU Osijek University Hospital, Croatia, data from electronic database May 2016 30 June 2023 were analyzed. In a cross-sectional study examining 15,790 microbiological samples, different strains observed 581 samples 236 patients....
Uvod: Koncept ujedinjene bolesti disajnih puteva prepoznat je pre više decenija, kod pacijenata sa astmom. Nedavna istraživanja su ukazala na prisustvo i znaþaj simptoma rinitisa obolelih hroniþnom opstruktivnom bolešüu pluüa. Cilj: Cilj bio da se proceni uticaj težinu HOBP pogoršanja. Materijal metode: U prospektivnu studiju ukljuþeno 49 pacijenata, 24 (48,98%) osobe ženskog 25 (51,02%) muškog pola, proseþne starosti 66,49±7,461 godina. Težina HOBP-a odreÿena spirometrijskim parametrom...
Abstract Background Previous studies on P. mirabilis strains isolated from Croatian healthcare institutions revealed the predominance of TEM-52 extended spectrum β-lactamase (ESBL), as well emergence plasmid AmpC β-lactamases. Our aim was to molecularly characterize cefalosporinases in isolates long-term care facilities (LTCFs) and compare their resistance profile dynamics with community isolates. Methods From a total 3,321 collected two LCTFs outpatients between 2015 2017, 1.23% them were...
Aim: The goal of this research is to examine the biofilm forming ability Staphylococcus aureus and Pseudomonas aeruginosa clinical isolates in different vitro conditions using Meuller-Hinton Luria-Bertani broths. Material methods: 30 strains obtained from specimens were used. After preparing suspensions bacteria inoculated on broths, they set microtiter plates the production was measured spectrophotometric reader 550 nm. Strains classified into four categories: non producing, weak...
Ziele: Papillome (PAP) der weiblichen Brust werden – im Unterschied zu Fibroadenomen (FA) häufig chirurgisch reseziert. Eine nicht invasive, prätherapeutische Differentialdiagnose zwischen diesen beiden Tumoren ist komplex, könnte jedoch potentiell die Indikation zur Operation beeinflussen.
Contemporary medicine is unimaginabile without biotechnological involvment in diagnostic and therapeutic purpouses, but sometimes the discovery application of new materials go faster then understanding adoption knowledge about consequences for our organism. Understanding biological processes at microscopycal molecular level would lead to better integration biomaterial with human body environment. The primary aim this review was evaluate potential microbiological effect after implant...