Kun Zhao

ORCID: 0000-0003-0711-7335
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Autophagy in Disease and Therapy
  • Adipose Tissue and Metabolism
  • Diet and metabolism studies
  • Inflammasome and immune disorders
  • Fault Detection and Control Systems
  • Ecology and Conservation Studies
  • Cancer-related molecular mechanisms research
  • Nanoplatforms for cancer theranostics
  • Medical Research and Treatments
  • Photoacoustic and Ultrasonic Imaging
  • Diabetes Management and Education
  • Traditional Chinese Medicine Analysis
  • Pharmacological Effects of Natural Compounds
  • Synthesis and properties of polymers
  • Adipokines, Inflammation, and Metabolic Diseases
  • Metabolism, Diabetes, and Cancer
  • GABA and Rice Research
  • Mesenchymal stem cell research
  • Immune cells in cancer
  • Anesthesia and Pain Management
  • Diabetes Treatment and Management
  • Congenital Diaphragmatic Hernia Studies
  • Cardiovascular Function and Risk Factors
  • Diabetes Management and Research

Shanghai Sixth People's Hospital
2023-2025

Shanghai Jiao Tong University
2023-2025

Nanjing Agricultural University
2022-2025

Hebei Medical University
2024

Second Hospital of Hebei Medical University
2024

Imaging Center
2023-2024

Nanjing Medical University
2024

Jiangsu Province Hospital
2024

Qingdao University
2014-2022

Anhui University of Science and Technology
2021

In order to investigate the mechanisms and therapeutic effects of valproate combined with lithium carbonate on mouse model Parkinson's disease (PD), male C57BL/6 mice were injected into intraperitoneal (20 μg/ml) (10 for 7 days following 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) (30 mg/kg) administration, motor function analyzed. Immunohistochemistry Western blotting used detect alterations in expression PD biomarkers, including tyrosine hydroxylase (TH), level autophagy was...

10.3109/00207454.2012.729234 article EN International Journal of Neuroscience 2012-09-17

Asarum forbesii is a perennial herb born in shaded and humid environment, which warm nature. With the efficacy of warming lung, resolving fluid retention, relieving coughs, it can be used to treat syndrome cold accumulating lung. To investigate effects different shading conditions on composition A. forbesii, this study planted under 20% natural light(NL20), 40% light(NL40), 60% light(NL60), 80% light(NL80) utilized ultra performance liquid chromatography(UPLC) micro broth 2-fold dilution...

10.19540/j.cnki.cjcmm.20241014.101 article EN PubMed 2025-01-01

The macrovascular complications of diabetes cause high mortality and disability in patients with type 2 mellitus (T2DM). inflammatory response vascular smooth muscle cell (VSMC) runs through its pathophysiological process. Salvianolic acid B (Sal B) exhibits beneficial effects on the cardiovascular system. However, role mechanism diabetic remain unclear. In this study, we found that Sal reduced inflammation mice glucose- (HG-) induced VSMC inflammation. Subsequently, HG-induced by...

10.1155/2024/4121166 article EN cc-by Mediators of Inflammation 2024-02-16

Lithium ion battery becomes the first choice of energy storage because its high density and long service life. The safety, operation, state estimation residual life prediction lithium system are managed by management (BMS), so BMS is very important for use stability system. represented power was focused on, application data-driven method in summarized. characteristics electrochemical model, equivalent circuit model electrical scope thermal coupling modeling were Kalman Filter, neural...

10.1117/12.2635069 article EN 2nd International Conference on Mechanical, Electronics, and Electrical and Automation Control (METMS 2022) 2022-04-25

This study aimed to prepare an anti-Vascular cell adhesion protein 1 (VCAM-1) nanoscale ultrasound microbubble contrast agent using the hyperbranched self-assembly method for molecular imaging diagnosis of atherosclerotic vulnerable plaques in rabbits. Twenty-five rabbits with carotid atherosclerosis were randomly divided into 5 groups, and ear vein was injected agents as follows: Groups A B: without anti-VCAM-1 agent; C D: SonoVue ultrasonic agent, Control group: saline. The plaque,...

10.31083/j.rcm2204173 article EN cc-by Reviews in Cardiovascular Medicine 2021-12-22

10.1001/jamainternmed.2024.4992 article EN JAMA Internal Medicine 2024-09-30

1School of Public Health, Harbin Medical University, Harbin, China 2Department Gastroenterology & Hepatology, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin 3Shanghai Jiao Tong University Affiliated Sixth People's Hospital South Campus, Shanghai, Correspondence Kun Zhao, Shanghai Jiaotong People Campus. No.6600. Nanfeng Highway, Fengxian District. 201499, China. Email: [email protected]

10.1097/hep.0000000000001164 article EN Hepatology 2024-11-12

Objective To explore the relationship between susceptibility loci polymorphism and bronchopulmonary dysplasia (BPD) in Han premature infants. Methods Twenty-eight genes were speculated to be associated with BPD development according literature.And 46 cases of infants, who hospitalized Guangdong General Hospital from April December 2013 whose gestational age≤32 weeks, birth weight (BW)≤1 500 g, prospectively selected into study after obtaining informed consents parents.Among them, 31...

10.3760/cma.j.issn.2095-428x.2015.04.005 article EN 2015-02-20

Light is the main source for plants to obtain energy.Asarum forbesii a typical shade medicinal plant, which generally grows in shady and wet place under bushes or beside ditches.It can grow develop without too much light intensity.This experiment explores effects of shading on growth, physiological characteristics energy metabolism A.forbesii, provide reference guidance its artificial planting.In this experiment, A.forbesii was planted 80%, 60%, 40%, 20% no shade.During vigorous growth...

10.19540/j.cnki.cjcmm.20220416.104 article EN PubMed 2022-08-01

Objective To investigate the value of magnetic resonance imaging (MRI) and diffusion-weighted (DWI) in diagnosis autoimmune pancreatitis (AIP). Methods Clinical data 11 patients pathologically diagnosed with AIP Sun Yat-sen Memorial Hospital, University from January 2013 to June 2014 were analyzed retrospectively. There 7 males 4 females a mean age (54±15) years old. The informed consents all obtained local ethical committee approval had been received. Apparent diffusion coefficient...

10.3877/cma.j.issn.2095-3232.2015.01.012 article EN Chin J Hepat Surg(Electronic Edition) 2015-02-10

Objective To investigate the possible mechanism of inhibitory effect stichopus japonicus acidic mucopolysaccharide (SJAMP) on proliferation in pancreatic carcinoma SW1990 cells.Methods cells were incubated with different concentrations SJAMP for 24,48,and 72 h.SW 1990 without treatment as control.RT-PCR was used to determine expression Hippo pathway members,including YAP,MST1 and related genes —— Survivin,TEAD1,Caspase-9,TEAD1 mRNA,and protein expressions YAP phosphorylated (p-YAP) detected...

10.3760/cma.j.issn.1674-1935.2014.01.011 article EN Chin J Pancreatol 2014-02-20

Observational studies have reported that COVID-19 is associated with alterations in retinal layer thickness, including changes the ganglion cell inner plexiform (GCIPL) and nerve fiber (RNFL). However, observational are susceptible to confounding factors reverse causality. Therefore, we assessed direction strength of causal relationship between patient phenotypes (susceptibility, hospitalization, severity) GCIPL RNFL thicknesses using a bidirectional two-sample Mendelian randomization (MR)...

10.22541/au.167612045.59448998/v1 preprint EN Authorea (Authorea) 2023-02-11

10.3724/j.issn.1000-0518.1990.5.4548 article EN Chinese Journal of Applied Chemistry 1990-10-01
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