A5100461432- Gout, Hyperuricemia, Uric Acid
- Chronic Kidney Disease and Diabetes
- Renal Diseases and Glomerulopathies
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Kidney Injury Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Sepsis Diagnosis and Treatment
- Trauma and Emergency Care Studies
- Porphyrin Metabolism and Disorders
- Dialysis and Renal Disease Management
- Ion Transport and Channel Regulation
- Bone and Joint Diseases
- Neonatal and fetal brain pathology
- Silymarin and Mushroom Poisoning
- Infant Nutrition and Health
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Parathyroid Disorders and Treatments
- Cardiovascular Function and Risk Factors
- Blood properties and coagulation
- Inflammasome and immune disorders
- Venous Thromboembolism Diagnosis and Management
- Healthcare and Venom Research
- Medical Research and Treatments
- Trace Elements in Health
- Osteoarthritis Treatment and Mechanisms
Nanjing Medical University
2023-2025
Kangda College of Nanjing Medical University
2025
Wenzhou Medical University
2021-2024
First Affiliated Hospital of Wenzhou Medical University
2021-2024
Air Force Medical University
2023
Capital Medical University
2015-2022
China Rehabilitation Research Center
2015-2022
Kunming Medical University
2022
Cangzhou Central Hospital
2022
Yan'an Hospital Affiliated To Kunming Medical University
2022
Abstract Introduction Early and aggressive volume resuscitation is fundamental in the treatment of hemodynamic instability critically ill patients improves patient survival. However, one important consequence fluid administration risk developing overload (FO), which associated with increased mortality acute kidney injury (AKI). We evaluated impact balance on intensive care unit (ICU) AKI. Methods The data were extracted from Beijing Acute Kidney Injury Trial. This trial was a prospective,...
To assess the value of combined Monocyte Distribution Width (MDW) and Procalcitonin (PCT) detection in diagnosing predicting neonatal sepsis outcomes. This retrospective study, conducted from January 2022 to December 2023.A analysis 39 30 non-infectious systemic inflammatory response syndrome (SIRS) cases was conducted. MDW, PCT, CRP levels were compared. Relationships between variables analyzed with Pearson correlation Cox regression models; diagnostic performance assessed using ROC curves....
IgA nephropathy (IgAN) is one of the most common types glomerulonephritis worldwide and diagnosed only with a renal biopsy. The purpose present studies was to identify potential biomarkers for non-invasive diagnosis IgAN. combination magnetic bead separation system matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) used analyze urinary peptides IgAN patients, other glomerulopathy healthy controls. ClinProTools v.2.0 software also applied establish...
A wide range of microalbuminuria cutoff values are currently used for diagnosing the early stage nephropathy in type 2 diabetes (T2D). This study analyzed relationships between oxidant and antioxidant markers severity microalbuminuria. The included 50 healthy controls (Group 1), diabetic patients with no 2), a urinary albumin excretion (UAE) 30-200 mg/24 h 3), UAE 200-300 4). Serum nitrotyrosine, conjugated dienes, 8-hydroxy-2'-deoxyguanosine (8-OHdG), superoxide dismutase (SOD), total...
BACKGROUND:Contrast-induced nephropathy (CIN) refers to acute renal damage that occurs after the use of contrast agents. This study investigated protective effect probucol in a rat model contrast-induced and mechanism its effect. MATERIAL AND METHODS:Twenty-eight Wistar rats were randomly divided into control group, N-acetylcysteine(NAC) group. We used iopromide-induced CIN. One day prior modeling, received gavage. At 24 h blood biochemistry urine protein assessed. Malondialdehyde (MDA)...
Objective: Previous studies on various enzymosomes (functional lipid vesicles encapsulating an enzyme) have been mostly carried out in vitro and focused preserving catalytic activity improving the stability of enzyme. Until now, few their vivo fate. Similarly, although we previously reported increased uricolytic (about 2.2 times higher than that free uricase, or three PEGylated Puricase ® , under physiological pH temperature) improved novel alkaline uricase from Candida utilis :...
Objective Traumatic brain injury (TBI) is a global social, economic, and health challenge that associated with premature death long-term disability. In the context of rapid development urbanization, analysis TBI rate mortality trend could provide abundant diagnosis treatment suggestions, which helps to form future reference on public strategies. Methods this study, as one major neurosurgical centers in China, we focused regime shift based 18-year consecutive clinical data evaluated...
Objective Serum chloride disorders have been gaining increased attention. We aimed to assess the impact of serum on all-cause mortality in critically ill patients coronary care units (CCUs). Methods extracted clinical data from Multiparameter Intelligent Monitoring Intensive Care III database. used for first CCU admission each patient; baseline were within 24 hours after admission. Statistical methods included Lowess smoothing technique, Cox proportional hazards model, and subgroup analyses....
Abstract Background In this study, we examine the association between hyperuricemia(HU) and hypertension(HTN) in Chinese young adults. Besides, correlation occurrence of thickened left ventricular wall HU was identified patients with HTN. Methods all, 360 HTN 1991 adults normal blood pressure(NBP) were enrolled study. Participant characteristics collected. Univariable multivariable logistic regression tests utilized to identify presence HTN, septum Results The prevalence significantly higher...
The study aimed to evaluate the effects of oral administration irbesartan in adriamycin-induced nephropathy considering laboratory changes, kidney histology, and expression proteins related slit diaphragm cytoskeleton podocyte.The animals were divided into control, model, methylprednisolone (MP), groups. 24-hour urinary protein biochemical indicators determined, renal pathological changes observed. mRNA nephrin, podocin, CD2-associated (CD2AP), desmin tissue analyzed.The excretion levels MP...
Background: Peritoneal dialysis (PD) is the main renal replacement therapy in elderly patients account for hemodynamic stability. The clinical characteristics and prognosis of PD are varies different centers. We analyzed characteristics, outcomes factors survival China, to better understand their status improve quality life.
Traditional Chinese medicine injections are new dosage forms of traditional in China.Compare with other such as tablets, pills and oral liquid, they have the advantage rapid onset.Injection drug ingredients can distribute target tissue or receptors, then onset quickly.Traditional suitable for rescuing patients a critical situation, intravenous delivery make liquid direct into circulatory system.The injection has adverse reactions, so it is particularly necessary to control quality evaluate...
Objective To explore whether changes of microalbuminuria are paralleled with the reduced glomerular filtration rate in type 2 diabetic patients. Methods A study was conducted 1 184 patients from 27 Beijing community clinics between Apr. 2013 and Mar. 2015. Data albumin/creatinine ratio (ACR), serum creatinine lipid profiles were collected. Estimated (eGFR) evaluated by Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), Cockcroft-Gault(CG), simplified Modification Diet Renal...
Although hyperuricemia (HU) has been reported to be related atrial fibrillation (AF), the relationship between HU and left (LA) enlargement is unclear. The aim of this study was investigate interaction LA in healthy adults China.This retrospectively surveyed 5,392 people (3,336 males 2,056 females) who underwent health checks. Basic data were obtained from all participants, including baseline characteristics general status through laboratory tests, echocardiography, interviews. Multinomial...
Objective To investigate the changes in serum cortisol and adrenocorticotrophic hormone(ACTH) levels children with steroid-sensitive nephritic syndrome(SSNS)and clinical significance of intervention. Methods According to whether a child SSNS would relapse, 48 were divided into non-recurrence group(n=19) recurrence group(n=29), at same time 14 age-matched healthy enrolled as control group.Serum ACTH measured patients by using electrochemiluminesence methods.In group, methylpredisolone...
Objective To explore the correlation between hyperuricaemia and blood pressure, lipid glucose. Methods By using simple cluster sampling, 2 branch units from PetroChina Changqing Oilfield Company were selected, all 720 subjects with (HUA) assigned to HUA group; another 620 participants normal uric acid (UA) level into group.The glucose was assessed by Logistic regression. Results The odds ratio (OR) of those who had 1, or 3 abnormal status hypertension, hyperlipidemia impaired...