A5009936892- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Chromosomal and Genetic Variations
- Genetic Syndromes and Imprinting
- Reproductive biology and impacts on aquatic species
- Evolution and Genetic Dynamics
- Animal Genetics and Reproduction
- CRISPR and Genetic Engineering
- Genetic diversity and population structure
Institute of Hydrobiology
2022-2025
Chinese Academy of Sciences
2022-2025
University of Chinese Academy of Sciences
2022-2024
State Key Laboratory of Freshwater Ecology and Biotechnology
2024
Abstract Triploids are rare in nature because of difficulties meiotic and gametogenic processes, especially vertebrates. The Carassius complex cyprinid teleosts contains sexual tetraploid crucian carp/goldfish ( C. auratus ) unisexual hexaploid gibel carp/Prussian carp gibelio lineages, providing a valuable model for studying the evolution maintenance mechanism polyploids Here we sequence genomes two species assemble their haplotypes, which contain subgenomes (A B), to chromosome level....
Abstract Sex chromosomes display remarkable diversity and variability among vertebrates. Compared with research on the X/Y Z/W chromosomes, which have long evolutionary histories in mammals birds, studies sex at early stages are limited. Here, we precisely assembled genomes of homozygous XX female YY male Lanzhou catfish (Silurus lanzhouensis) derived from an artificial gynogenetic family a self-fertilized family, respectively. Chromosome 24 (Chr24) was identified as chromosome based...
Hypoxic stress causes cell damage and serious diseases in organisms, especially aquatic animals. It is important to elucidate the changes metabolic function caused by hypoxia mechanisms underlying these changes. This study focuses on low oxygen tolerance feature of a new blunt snout bream strain (GBSBF1). Our data show that GBSBF1 has different lipid carbohydrate metabolism pattern than wild-type bream, with altering glycolysis synthesis. In GBSBF1, expression levels phd2 vhl genes are...
Although evolutionary fates and expression patterns of duplicated genes have been extensively investigated, how co-regulate a biological process in polyploids remains largely unknown. Here, we identified two gsdf (gonadal somatic cell-derived factor) homeologous (gsdf-A gsdf-B) hexaploid gibel carp (Carassius gibelio), wherein each homeolog contained three highly conserved alleles. Interestingly, gsdf-A gsdf-B transcription were mainly activated by dmrt1-A (dsx- mab-3-related factor 1)...
Genome duplication supplies raw genetic materials and has been thought to be essential for evolutionary innovation ecological adaptation. Here, we select Kelch-like (klhl) genes study the evolution of duplicated in polyploid Carassius complex, including amphidiploid C. auratus amphitriploid gibelio. Phylogenetic, chromosomal location read coverage analyses indicate that most klhl exhibit a 2:1 relationship with zebrafish orthologs confirm two rounds polyploidy, an allotetraploidy followed by...