Highlights•Parabacteroides distasonis alleviates obesity and obesity-related dysfunctions in mice.•P. generates succinate secondary bile acids the gut.•P. activates intestinal gluconeogenesis (IGN) FXR pathways gut.•Succinate is a ligand of fructose-1,6-bisphosphatase, rate-limiting enzyme IGN.SummaryWe demonstrated metabolic benefits Parabacteroides (PD) on decreasing weight gain, hyperglycemia, hepatic steatosis ob/ob high-fat diet (HFD)-fed mice. Treatment with live P. (LPD) dramatically...

A chameleon under pressure: The observed piezochromic behavior of the title compound (BP2VA) was found to depend on its molecular aggregation state and specifically strength π–π interaction between anthracene rings adjacent molecules. When BP2VA is ground or placed pressure, changes, a red shift in fluorescence emission from green via orange occurs (see picture). Detailed facts importance specialist readers are published as "Supporting Information". Such documents peer-reviewed, but not...

A novel divinylanthracene derivative 9,10-bis((E)-2-(pyridin-4-yl)vinyl)anthracene (BP4VA) was synthesized and its two polymorphs with different crystal structures were obtained. The introduction of pyridine in BP4VA leads to multi-stimuli responsive fluorescence. An investigation the photophysical stimuli luminescent properties BP4VA, including piezochromism protonation effect, demonstrates that piezochromic luminescence originates from changes molecular aggregation state. Additionally,...

Herein, we report an anthracene-based material, 2-(anthracen-9-yl)thianthrene (), whose crystal exhibits excimer fluorescence with unexpected high luminous efficiency (up to 80%) and long lifetime (163.75 ns), due pairwise anthracene stacking. These results will update the traditional view that excimers are poorly efficient in photoluminescence.

Abstract Incorporating synthetic macrocycles with unique structures and distinct conformations into conjugated macrocycle polymers (CMPs) can endow the resulting materials great potentials in gas uptake pollutant adsorption. Here, four CMPs (CMP‐n, n=1–4) capable of reversibly capturing iodine efficiently separating carbon dioxide are constructed from per‐triflate functionalized leaning tower[6]arene (LT6‐OTf) [2]biphenyl‐extended pillar[6]arene (BpP6‐OTf) via Pd‐catalyzed...

Microplastics (MPs) as emerging contaminants have become a global environmental problem. However, studies on the effects of MPs metabolic diseases remain limited. Here, we evaluated polystyrene (PS), one most prominent types MPs, insulin sensitivity in mice fed with normal chow diet (NCD) or high-fat (HFD), and explained underlying mechanisms. Mice NCD HFD both showed resistance (IR) after PS exposure accompanied by increased plasma lipopolysaccharide pro-inflammatory cytokines such tumor...

Abstract Controlling vertical phase separation of the active layer to enable efficient exciton dissociation and charge carrier transport is crucial boost power conversion efficiencies (PCEs) pseudoplanar heterojunction (PPHJ) organic solar cells (OSCs). However, how optimize PPHJ OSCs via molecule design rarely reported yet. Herein, ternary polymerization strategy employed develop a series polymer donors, DL1‐DL4, regulate their solubility, molecular aggregation, orientation, miscibility,...

Abstract Sensitive and stable perovskite X-ray detectors are attractive in low-dosage medical examinations. The high sensitivity, tunable chemical compositions, electronic dimensions, low-cost raw materials make perovskites promising next-generation semiconductors. However, their ionic nature brings serious concerns about water stability, limiting applications well-established technologies like crystal polishing, micro-processing, photolithography, etc. Herein we report a one-dimensional...

Strong supramolecular interactions, which induced tight packing and rigid molecules in crystals of cyano substituent oligo(para-phenylene vinylene) (CN-DPDSB), are the key factor for high luminescence efficiency its crystals; opposite to isolated solution have very low efficiency.

From the inside out: Hollow ferrocenyl coordination polymer microspheres with microporous shells were prepared by a convenient and template-free approach. An Ostwald ripening mechanism is responsible for formation of hollow cavities. The hierarchically have potential applications in catalysis, drug delivery, hydrogen storage.

• Drought induces root death in plants; however, the nature and characteristics of cell its underlying mechanisms are poorly understood. Here, we provide a systematic analysis primary tips Arabidopsis during water stress. Root tip occurs when high deficit is reached. The dying cells were first detected apical meristem roots underwent active programmed (PCD). Transmission electron microscopic shows that undergoing induced had unambiguous morphological features autophagic death, including an...

ConspectusThe combination of rational design building components and suitable utilization driving force affords spontaneous molecular assemblies with well-defined nanostructure morphology over multiple length scales. The serious challenges in constructing structural advantages for the realization functions programmed into usually lie ahead since process that occurs does not always follow expected roadmap absence external intervention. Thus, prefabricated intermediates help governing target...

Cross dipole stacking based on a novel fluorescent molecule, 9,10-bis (2,2-diphenylvinyl) anthracene (BDPVA), is presented. The butterfly-like structure of BDPVA the key feature to form unique aggregation and such mode highly beneficial for fluorescence emission, resulting in high-performance amplified spontaneous emission electroluminescence BDPVA.

In this work, a novel version of macrocyclic arenes, namely leaning pillar[6]arenes, was discovered and it can be considered as tilted pillar[6]arene with two hydroxy/alkoxy functionalities removed. Through facile two-step synthetic approaches, in conjunction diversity post-modification possibilities, series good cavity adaptability enhanced guest-binding capability, synthesized, their self-assembly single-crystal states is presented. DFT calculations demonstrated that the lower rotational...

The mechanochromic property of tetrakis(4-(dimethylamino)phenyl)ethylene (TDMAPE) with natural propeller shape and nearly centrosymmetric structure was investigated. destruction the crystalline leads to planarization molecular conformation, which is considered as a possible reason for red-shift absorption fluorescence spectra after grinding. And polymorphism-dependent emissions two polymorphs TDMAPE are mainly determined by intramolecular show increased coplanarity or conjugation degree,...

Smart POMs: A surfactant-encapsulated organic-grafted polyoxometalate (POM) is synthesized by grafting a photoresponsive azobenzene group to an Anderson-type POM cluster. Self-assemblies of the hybrid complexes exhibit photocontrolled reversible aggregation and morphological change as result photoisomerization-induced structural alternation (see figure).

Ein Chamäleon unter Druck: Das beobachtete piezochrome Verhalten der Titelverbindung (BP2VA) hängt von ihrem molekularen Aggregationszustand ab, insbesondere Stärke π-π-Wechselwirkung zwischen den Anthracenringen benachbarter Moleküle. Beim Zermahlen BP2VA oder bei Einwirkung Druck ändert die Verbindung ihren Aggregationszustand, begleitet einer Rotverschiebung Fluoreszenzemission Grün über Orange nach Rot (siehe Bild). Detailed facts of importance to specialist readers are published as...

Insights into the origin of fluorescence responsive to protonation-deprotonation stimuli were provided through study on crystals a new stimuli-responsive molecule BP3VA. And transformation between microcrystals demonstrated varying emissions BP3VA powder.

Haloalkanes are important chemicals in synthetic chemistry and petrochemical industry, but the separation of their isomers is a big hurdle. Herein, we report facile energy-efficient adsorptive strategy using new class nonporous adaptive crystals based on leaning pillar[6]arene. Desolvated perethylated pillar[6]arene (EtLP6) with interesting character show preference for 1-bromoalkane over 2-bromoalkane isomers. EtLP6 capable separating 1-bromopropane, 1-bromobutane, 1-bromopentane from...

High-efficiency excimer fluorescence of <bold>mTPA-9-AN</bold> is realized by a thermally-activated phase transition process.

Abstract Extending π‐conjugation of donor units in fused ring electron acceptors (FREAs) promises to reinforce intramolecular charge transfer for smaller bandgaps, and enhances intermolecular interactions higher mobility. Despite these advantages, power conversion efficiencies (PCEs) FREAs with a large planar core are still below 12%. Herein, decacyclic unit, IDC, is developed, the FREA, IDCIC, whose optical bandgap 1.45 eV, synthesized. The FTAZ:IDCIC‐based organic solar cell (OSC) binary...