A5006843396- Renal cell carcinoma treatment
- Cancer Immunotherapy and Biomarkers
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Renal and related cancers
- MicroRNA in disease regulation
- Bladder and Urothelial Cancer Treatments
- Circular RNAs in diseases
- Epigenetics and DNA Methylation
- Ferroptosis and cancer prognosis
- Sexual function and dysfunction studies
- Urinary and Genital Oncology Studies
- Renal Transplantation Outcomes and Treatments
- Perovskite Materials and Applications
- Traditional Chinese Medicine Analysis
- Cytomegalovirus and herpesvirus research
- Cancer, Lipids, and Metabolism
- RNA Research and Splicing
- Natural product bioactivities and synthesis
- Mycobacterium research and diagnosis
- Cancer-related molecular mechanisms research
- Urinary Bladder and Prostate Research
- RNA Interference and Gene Delivery
- Immune cells in cancer
- Plant biochemistry and biosynthesis
Shenyang Pharmaceutical University
2021-2025
Jilin University
2017-2025
State Key Laboratory of Supramolecular Structure and Materials
2017-2025
Soochow University
2013-2024
First Affiliated Hospital of Soochow University
2011-2024
Nankai University
2024
Shandong University of Technology
2022
Suzhou Research Institute
2020
Henan University of Science and Technology
2018
Abstract Sensitive and stable perovskite X-ray detectors are attractive in low-dosage medical examinations. The high sensitivity, tunable chemical compositions, electronic dimensions, low-cost raw materials make perovskites promising next-generation semiconductors. However, their ionic nature brings serious concerns about water stability, limiting applications well-established technologies like crystal polishing, micro-processing, photolithography, etc. Herein we report a one-dimensional...
Abstract Given the promising application prospects of underwater X‐ray detection technology, traditional perovskite materials, despite their outstanding performance in detection, are significantly constrained by inherent susceptibility to hydrolysis, hindering effective utilization environments. To date, most efforts devoted evaluating these materials' under atmospheric conditions, with a limited exploration into adaptability settings. In this study, successful fabrication thick...
A high performance ratiometric fluorescent probe, namely TPE-RNS, has been developed for detecting exogenous and endogenous HClO/ClO<sup>−</sup> in living cells discriminating cancer from normal cells.
Patterned arrays of perovskite single crystals can avoid signal cross-talk in optoelectronic devices, while precise crystal distribution plays a crucial role enhancing device performance and uniformity, optimizing photoelectric characteristics, improving optical management. Here, we report strategy droplet-assisted self-alignment to precisely assemble the single-crystal (PSCAs). High-quality hybrid methylammonium lead bromide (MAPbBr
Abstract Smart pH‐responsive surfaces that could autonomously induce unidirectional wetting of acid and base with reversed directions are fabricated. The smart surfaces, consisting chemistry‐asymmetric “Janus” silicon cylinder arrays (Si‐CAs), prepared by precise modification functional groups on each unit. Herein, amino carboxyl chosen as typical groups, owing to their protonation/deprotonation effect in response pH the contacted aqueous solution. One side Si‐CAs is modified...
Background: B7-H3 (or CD276) represents an important costimulatory molecule expressed in many malignant solid tumors, including colorectal cancer (CRC). The receptor of is not known, and the intracellular function remains obscure. Herein, we report that upregulated epidermal growth factor heparin-binding (HB-EGF), likely by regulating hypoxia-inducible 1α (HIF-1α) thereby promoting progression CRC. Methods: Lentiviral transfection was performed on CRC cells to establish stable low-B7-H3...
This study aimed to explore the effect of CD276 expression on sunitinib sensitivity clear cell renal carcinoma (ccRCC) and animal models potential mechanisms involved.
BACKGROUND Prostate cancer (PCa) is a widespread malignancy, predominantly affecting elderly males, and current methods for diagnosis treatment of this disease continue to fall short. The marker Ki-67 (MKI67) has been previously demonstrated correlate with the proliferation metastasis various cells, including those PCa. Hence, verifying association between MKI67 prognosis PCa, using bioinformatics databases clinical data analysis, carries significant implications. AIM To explore diagnostic...
Objective This study aimed to explore the relationship between CD276 and clear cell renal carcinoma (ccRCC) assess diagnostic value of in ccRCC. Methods Expression levels ccRCC para-cancer tissues were compared analyzed retrospectively using data obtained from TCGA GEO databases. The clinical was prospectively. Immunohistochemistry RT-PCR analyses used analyze expression at mRNA protein levels. These 70 patients with Next, ELISA peripheral blood samples 72 healthy individuals, facilitating...
Objective: To investigate the effect of long noncoding RNA GM16343 on interleukin 36β promotion CD8 + T cells in tumor microenvironment regulation. Methods: The differentially expressed 36β-stimulated mouse was screened by gene chip technology, and significant RNAs were verified real-time polymerase chain reaction. lentiviral vector that overexpresses or knockdown constructed, transfected into cells, stimulated with 36β, amount interferon γ secreted detected enzyme-linked immunosorbent...
Immunotherapy is a new and powerful weapon against tumors, represented by inhibitors of programmed death-1 (PD-1) cytotoxic T lymphocyte-associated protein-4 (CTLA-4). This study aimed to determine the similarities differences between PD-1 CTLA-4 in 33 cancers The Cancer Genome Atlas (TCGA) impact subtypes immune environment on tumor production treatment.From Xena browser, we downloaded TNM stage, subtypes, microenvironment scores for tumors from TCGA. Expression normal samples were compared...
Abstract Background Colon cancer is a common malignant tumor of the digestive tract, and its incidence ranked third among gastrointestinal tumors. The present study aims to investigate role novel circular RNA (circCSPP1) in colon underlying molecular mechanisms. Methods Bioinformatics analysis reverse transcription-quantitative PCR were used detect expression levels circCSPP1 tissues cell lines. effects on behavior cells investigated using CCK-8, transwell clonogenic assays. along with...
The role of a long non-coding RNA called small nucleolar host gene 25 (SNHG25) has been studied in some tumor types but the correlation between SNHG25 and PCA remains unknown. relationship clinicopathologic characteristics expression was evaluated using Cancer Genome Atlas data. binary classifier value calculated areas under receiver operating characteristic (ROC) curves. Outcomes were Kaplan-Meier Cox regression analyses. Gene set enrichment performed to identify potential functions....
Epirubicin, gemcitabine, and pirarubicin are widely used as first-line drugs for intravesical chemotherapy to prevent tumor recurrence after transurethral bladder resection non-muscle-invasive cancer (NMIBC). However, which drug is better less discussed. A total of 335 NMIBC patients administered underwent (TURBT) in our hospital from October 2015 2019. After TURBT, all the received standard chemotherapy. Through clinical data collection telephone follow-up, adverse reactions perfusion...