A5058112082- Probiotics and Fermented Foods
- Natural product bioactivities and synthesis
- Gut microbiota and health
- Traditional Chinese Medicine Analysis
- Salmonella and Campylobacter epidemiology
- Immunotherapy and Immune Responses
- RNA Interference and Gene Delivery
- Food composition and properties
- Advanced Drug Delivery Systems
- Bacteriophages and microbial interactions
- Climate change impacts on agriculture
- Leaf Properties and Growth Measurement
- Urban Heat Island Mitigation
- Greenhouse Technology and Climate Control
- Platelet Disorders and Treatments
- Pancreatic function and diabetes
- Genetic Mapping and Diversity in Plants and Animals
- Clostridium difficile and Clostridium perfringens research
- Diabetes and associated disorders
- Remote Sensing in Agriculture
- Land Use and Ecosystem Services
- Hemophilia Treatment and Research
- Chronic Myeloid Leukemia Treatments
- Rice Cultivation and Yield Improvement
- Pineapple and bromelain studies
Xian Central Hospital
2024
Xi'an Jiaotong University
2024
Institute of Microbiology
2021-2023
Guangdong Academy of Sciences
2021-2023
State Key Laboratory of Food Science and Technology
2021-2022
Jiangnan University
2021-2022
Ministry of Agriculture and Rural Affairs
2021-2022
Agricultural Information Institute
2018-2021
Chinese Academy of Agricultural Sciences
2018-2021
Guangdong Medical College
2020
Salmonella is a widely distributed foodborne pathogen. The use of phages as biocontrol agents has recently gained significant interest. Because the genus high diversity, efforts are necessary to identify lytic focusing on different serovars. Here, five were isolated from soil samples, and vB_SalP_TR2 was selected novel phage with potential against host serovar Albany, well other tested serovars, including Corvallis, Newport, Kottbus, Istanbul. Morphological analyses demonstrated that belongs...
Chitosan (CS) has been extensively used as a protein drug and gene delivery carrier, but its efficiency is unsatisfactory. In this study, mannose ligand was to modify CS, which could enhance the of CS via receptor-mediated endocytosis. A preventative anti-GRP DNA vaccine (pCR3.1-VS-HSP65-TP-GRP6-M2, pGRP) condensed with mannosylated chitosan (MCS) form MCS/pGRP nanoparticles. Nanoparticles were intranasally administered in subcutaneous mice prostate carcinoma model evaluate efficacy on...
Waterlogging is becoming an obvious constraint on food production due to the frequent occurrence of extremely high-level rainfall events. Leaf water content (LWC) important waterlogging indicator, and hyperspectral remote sensing provides a non-destructive, real-time reliable method determine LWC. Thus, based pot experiment, winter wheat was subjected different gradients stress at jointing stage. data LWC were collected every 7 days after treatment until mature. Combined with methods such as...
Aging-induced bone loss is a multifactorial, age-related, and progressive phenomenon among the general population may further progress to osteoporosis increase risk of fractures. Cycloastragenol (CAG), currently only compound reported that activates human telomerase, thought be able alleviate or delay symptoms aging chronic diseases. Previous research has suggested CAG have potential age-related loss. However, date, no specifically focused on this aspect. In study, we aimed investigate...
Fermented milk is beneficial for metabolic disorders, while the underlying mechanisms of action remain unclear. This study explored benefits and Bifidobacterium longum 070103 fermented (BLFM) in thirteen-week high-fat high-sugar (HFHS) fed mice using omics techniques.BLFM with activated glucokinase (GK) was screened by a double-enzyme coupling method. After supplementing BLFM 10 mL/kg BW per day, fasting blood glucose, total cholesterol (TC), low-density lipoprotein (LDL-C), leptin were...
The vacant house is an essential phenomenon of urban decay and population loss. Exploration the correlations between housing vacancy some socio-environmental factors conducive to understanding mechanism shrinking revitalization. In recent years, rapidly developing night-time remote sensing, which has ability detect artificial lights, been widely applied in applications associated with human activities. Current sensing studies on rates are limited by coarse spatial resolution data. launch...
In this study, the potential climate change impacts on rice growth and yield under 1.5 2.0 °C warming scenarios, respectively, are simulated using Ceres-Rice Model based high-quality, agricultural, experimental, meteorological soil data, incorporation of future data generated by four Global Climate Models (GCMs) in Pearl River Delta, China. The climatic is extracted from namely: Community Atmosphere 4 (CAM4), European Centre for Medium-Range Weather Forecasts-Hamburg 6 (ECHAM6),...
Bifidobacterium , an important genus for human health, is difficult to isolate. We applied metagenomics, pangenomics, and enzymology determine the dominant glycoside hydrolase (GH) families of designed selective medium isolation. Pangenomics results showed that GH13, GH3, GH42, GH43 were highly conserved in . Metagenomic analysis GH faecal samples was performed. The indicated contains core GHs utilizing raffinose, D-trehalose anhydrous, D(+)-cellobiose, melibiose, lactulose, lactose,...
Ultrasound-assisted extraction (UAE) of total monoterpene glycosides extract (TMGE) from oil peony seed cakes was investigated. The yield optimized using response surface methodology (RSM). chemical constituents the were isolated by repeated column chromatography, and contents main in determined HPLC. optimum conditions as follows: a liquid-to-solid ratio 27 mL/g, ultrasonic time 16 min, temperature 26 °C, ethanol concentration 67%. Under these conditions, TMGE 10.24%. Twenty cakes,...
Pan-genome analysis identified genes specific to Salmonella serogroups B, C1, C2, D, E, and S. enteritidis . Three multiplex PCR assays for detecting five (B, E) two serovars ( typhimurium ) were sufficiently rapid.
Expression and purification of β-galactosidases derived from Bifidobacterium provide a new resource for efficient lactose hydrolysis intolerance alleviation. Here, we cloned expressed two Bifidobacterium. The optimal pH BLGLB1 was 5.5, the temperature 45 °C, at which enzyme activity higher than that commercial E (300 ± 3.6 U/mg) under its conditions, reaching 2200 15 U/mg. BPGLB1 were 6.0 respectively, (0.58 0.03 optimum conditions significantly lower BLGLB1. structures β-galactosidase...
The β-subunit of human chorionic gonadotropin (β-hCG) is ectopically expressed in various types cancer and has been utilized as an antigenic target anti-cancer vaccines. In view the low immunogenicity this self-peptide, we designed a method based on isocaudamer technique to generate 14 tandem repeats 10-residue sequence X β-hCG (109-118). These tandemly repeated copies were then combined with C-terminal 37 peptides (CTP37) finally fused mycobacterial heat-shock protein 65 (HSP65) construct...
Increasing temperatures, greater carbon dioxide concentrations, and changes in related climatic variables will continue to affect the growth yields of agricultural crops. Rice (Oryza sativa L.) is extremely vulnerable these changes. Therefore, investigating degree which climate could influence rice what effective adaptive strategies be taken mitigate potential adverse impacts vital importance. In this article, change on Zhejiang province, China, were simulated under Representative...
Many studies have obtained high-quality plant point clouds but it remains difficult to extract the midrib from a leaf cloud. In this study, fast and accurate approach extraction of was developed. The converted into its principal component analysis (PCA) coordinates find tip base points leaf. A new search algorithm proposed, which quickly searched for approximate shortest curve between on then projected fitted eliminate deviation midrib. Two types cloud, generated using structure-from-motion...
The extracellular secreted protein of Bifidobacterium longum (B. longum) plays an important role in maintaining the homeostasis human intestinal microenvironment. However, mechanism(s) interaction remain unclear. Lysozyme is a kind antibacterial peptide. In this study, amino acid sequence lysozyme-like B. based on whole-genome data isolate from gut feces was found. We further predicted functional domains sequence, purified protein, and verified its bioactivity. growth some bacteria were...
Objective Raising awareness of acquired hemophilia A (AHA) and early diagnosis is critical to reduce the associated mortality rate. We aimed characterize in Chinese patients evaluate effectiveness immunotherapy. Methods The clinical characteristics, laboratory test data, therapeutic approaches, outcomes 20 with AHA who were admitted Xi’an Central Hospital between January 2012 December 2020 retrospectively studied. Results Nine (45%) treated by single glucocorticoid administration; three...