A5082147582- Advanced Glycation End Products research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Research
- Extracellular vesicles in disease
- Cancer-related molecular mechanisms research
- Diet, Metabolism, and Disease
- Liver Disease Diagnosis and Treatment
- Pregnancy and preeclampsia studies
- Epigenetics and DNA Methylation
- Alcohol Consumption and Health Effects
- Metabolism, Diabetes, and Cancer
Cape Peninsula University of Technology
2021-2025
South African Medical Research Council
2021-2025
Stellenbosch University
2018
National Health Laboratory Service
2018
Glycated haemoglobin (HbA1c) has shown disagreements with other glycaemic indices; termed the glycation gap. The gap can be influenced by non-glycaemic factors like protein deglycation, through fructosamine 3 kinase (FN3K) enzyme. This cross-sectional study aimed to examine whether single nucleotide polymorphisms (SNPs) in FN3K gene explain Amongst 826 participants, 79.8% were female, 22.3% presented DM and median age was 53 years. results suggest that genetic may influence individuals...
<p dir="ltr">Glycated haemoglobin (HbA1c) has shown disagreements with other glycaemic indices; termed the glycation gap. The gap can be influenced by non-glycaemic factors like protein deglycation, through fructosamine 3 kinase (FN3K) enzyme. This cross-sectional study aimed to examine whether single nucleotide polymorphisms (SNPs) in FN3K gene explain Amongst 826 participants, 79.8% were female, 22.3% presented DM and median age was 53 years. results suggest that genetic may...
<p dir="ltr">Glycated haemoglobin (HbA1c) has shown disagreements with other glycaemic indices; termed the glycation gap. The gap can be influenced by non-glycaemic factors like protein deglycation, through fructosamine 3 kinase (FN3K) enzyme. This cross-sectional study aimed to examine whether single nucleotide polymorphisms (SNPs) in FN3K gene explain Amongst 826 participants, 79.8% were female, 22.3% presented DM and median age was 53 years. results suggest that genetic may...
The burden of chronic kidney disease (CKD) in Africa remains poorly characterized, due partly to the lack appropriate diagnostic strategies. Although recent years and prognostic utility microRNAs (miRNAs) have gained prominence context CKD, its value has not been evaluated African populations. We investigated expression whole blood miRNAs (miR-126-3p, -30a-5p, -1299, -182-5p -30e-3p) a total sample 1449 comprising 13.3% individuals with CKD (stage 1-5) 26.4% male participants, as well...
The asymptomatic nature of and lack effective early-stage diagnostic tools in CKD, predisposes individuals to the risk end-stage CKD related complications. Whole blood microRNAs (miRNAs) have potential for screening. We evaluated expression profile six novel whole miRNAs as well their ability predict prevalent with hypertension and/or diabetes. included 911 diabetes, which 18.8% had CKD. miRNA was analyzed using quantitative reverse transcription PCR (RT-PCR). Five miRNAs, namely...
This paper highlights the present condition of slum dwellers in Greater Mumbai (i.e.Mumbai City and suburbs), irrespective status as defined by Census, 2011, culling data from a recently published survey.A sample survey was conducted involving 525 households 22 urban slums city.Both qualitative quantitative methods were used, bivariate analysis techniques including chi square; two-way factorial ANOVA stepwise multiple regression used to understand differences quality life its domains across...