Shuai Chen

ORCID: 0000-0003-0745-9546
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Intestinal and Peritoneal Adhesions
  • Abdominal Surgery and Complications
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Particle Detector Development and Performance
  • Dark Matter and Cosmic Phenomena
  • Appendicitis Diagnosis and Management
  • Single-cell and spatial transcriptomics
  • Prostate Cancer Treatment and Research
  • Radiation Detection and Scintillator Technologies
  • Computational Drug Discovery Methods
  • GaN-based semiconductor devices and materials
  • Cancer, Lipids, and Metabolism
  • Enhanced Recovery After Surgery
  • IL-33, ST2, and ILC Pathways
  • Power System Optimization and Stability
  • Inflammasome and immune disorders
  • Autophagy in Disease and Therapy
  • Hernia repair and management
  • Advanced Computational Techniques and Applications
  • Cancer Mechanisms and Therapy
  • Soil Moisture and Remote Sensing
  • Adaptive Dynamic Programming Control
  • Ga2O3 and related materials
  • Head and Neck Anomalies
  • MicroRNA in disease regulation

Union Hospital
2022-2025

Guangxi University of Chinese Medicine
2025

Guangxi Medical University
2020-2025

Yunnan University of Traditional Chinese Medicine
2025

Shanghai Jiao Tong University
2022-2025

North China University of Science and Technology Affiliated Hospital
2024

North China University of Technology
2024

Guangxi University
2016-2024

Fujian Medical University
2022-2023

Chengdu University of Traditional Chinese Medicine
2023

Monocyte-to-lymphocyte ratio (MLR), neutrophil-to-lymphocyte (NLR), platelet-to-lymphocyte (PLR) are acknowledged as novel inflammatory markers. However, studies investigating the correlation between markers and osteoporosis (OP) remain scarce. We aimed to investigate relationship NLR, MLR, PLR bone mineral density (BMD).A total of 9054 participants from National Health Nutrition Examination Survey were included in study. NLR calculated for each patient based on routine blood tests. Given...

10.1186/s13018-023-03795-5 article EN cc-by Journal of Orthopaedic Surgery and Research 2023-04-17

As industrial pollution intensifies, global male semen quality has been declining at a rate of 2.64 % per year in the 21st century. Among various types infertility, non-obstructive azoospermia (NOA) is most severe and closely associated with exposure to environmental toxins. The molecular mechanisms by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), typical persistent organic pollutant, induces NOA have yet be systematically elucidated. This study employed single-sample Gene Set Enrichment...

10.1016/j.ecoenv.2025.118173 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2025-04-01

An integrated system has been developed for discovering potent inhibitors of severe acute respiratory syndrome coronavirus 3C-like protease (SARS-CoV 3CL(pro)) by virtual screening correlating with surface plasmon resonance (SPR) and fluorescence energy transfer (FRET) technologies-based assays. The authors screened 81,287 small molecular compounds against SPECS database screening; 256 were subsequently selected biological evaluation. Through SPR technology-based assay, 52 from these...

10.1177/1087057106293295 article EN cc-by-nc-nd SLAS DISCOVERY 2006-11-09

10.1016/j.nima.2023.168499 article EN Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment 2023-07-01

Acupuncture is often used as an adjunctive therapy for gastric ulcer (GU). However, there still a lack of evidence on the appropriate and optimal interventions acupuncture. This study aimed to optimize acupuncture treatment ulcers based expert consensus guiding acupuncturists in clinical practice.To conduct this study, research was gathered from databases both Chinese English. After discussion, preliminary questions were developed. Following three rounds multidisciplinary consultation,...

10.1016/j.ctim.2023.102997 article EN cc-by-nc-nd Complementary Therapies in Medicine 2023-10-21

Transition Radiation (TR) plays an important role in particle identification high-energy physics and its characteristics provide a feasible method of energy calibration the range up to 10 TeV, which is interest for dark matter searches cosmic rays. In Detector (TRD), TR signal superimposed onto ionization loss induced by incident charged particles. order make stand out from background significant way, we optimized both radiators detector. We have designed new prototype regular radiator...

10.1016/j.nima.2020.163723 article EN cc-by-nc-nd Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment 2020-03-02

Background: 2-Dodecyl-6-Methoxycyclohexa-2, 5-Diene-1,4-Dione (DMDD) was purified from the roots of Averrhoa carambola L. Previous research demonstrated that DMDD is a small molecular compound with significant therapeutic potential for tumors. However, targets and pharmacological mechanism to treat lung cancer has not been reported. Methods: We employed network pharmacology experimental evaluation reveal against cancer. Potential were screened by PharmMapper. Differentially expressed genes...

10.3389/fphar.2021.617555 article EN cc-by Frontiers in Pharmacology 2021-02-02

Distinguishing strangulated bowel obstruction (StBO) from simple (SiBO) still poses a challenge for emergency surgeons. We aimed to construct predictive model that could distinctly discriminate StBO SiBO based on the degree of ischemia.The patients diagnosed with intestinal were enrolled and divided into group group. Binary logistic regression was applied identify independent risk factors, then models radiological multi-dimensional constructed. Receiver operating characteristic (ROC) curves...

10.1186/s12876-022-02363-1 article EN cc-by BMC Gastroenterology 2022-06-22

Background This study aimed to explore predictive biomarkers of coronary collateralization in patients with chronic total occlusion. Methods and Results By using a microarray expression profiling program downloaded from the Gene Expression Omnibus database, weighted gene coexpression network analysis was constructed analyze relationship between potential modules screen out hub genes. Then, identified validated an independent cohort (including 299 good arteriogenic responders 223 poor...

10.1161/jaha.122.027614 article EN cc-by-nc-nd Journal of the American Heart Association 2022-12-14

Diabetes mellitus (DM) is an independent risk factor for cognitive impairment. Although the etiology of diabetic impairment complex and multifactorial, hippocampus neuronal apoptosis recognized as a main cause diabetes-induced 2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione (DMDD) was purified from roots Averrhoa carambola L. Previous research demonstrated that DMDD safe effective in delaying some complications. However, efficacy to ameliorate type 2 diabetes mice has not been reported. In...

10.3389/fphar.2021.708141 article EN cc-by Frontiers in Pharmacology 2021-12-16

This study comprehensively evaluates four satellite precipitation estimates (SPE) of the version 6 (V06) Integrated Multi-satellite Retrievals for Global Precipitation Measurement Mission (IMERG) at hourly scale in upper Red River Basin (URRB), located Yunnan, by applying 12 rain gauges during rainy season (May to October) from 2019 2020. Four SPE includes IMERG-E, IMERG-L, IMERG-FU and IMERG-FC, with IMERG-FC is calibrated Climatology Centre (GPCC) gauge. Due complex terrain URRB, we divide...

10.1080/2150704x.2021.2014076 article EN Remote Sensing Letters 2022-01-06

Nasointestinal tubes (NITs) have been increasingly used in patients with small bowel obstruction (SBO); However, severe adverse events (SAEs) of NITs might threaten the lives patients. The indications need to be identified. This study was designed explore for insertion SBO and suggest optimal strategies individuals based on outcomes SAEs.After propensity score matching, 68 pairs were included (Success group failure group). occurrence SAEs clinical parameters compared between SAE non-SAE...

10.1186/s12876-022-02405-8 article EN cc-by BMC Gastroenterology 2022-07-07

Abstract Background Some bladder-related diseases, such as bladder urinary tract infection (UTI) and cancer (BCa), have significant six differences in incidence prognosis. However, the molecular mechanisms underlying these sex are still not fully understood. Understanding sex-biased gene expression normal cells can help resolve problems. Methods We first collected published single-cell RNA sequencing (scRNA-seq) data of human bladders from females males to map transcriptomic landscape. Then,...

10.1186/s12920-023-01535-6 article EN cc-by BMC Medical Genomics 2023-06-05

Micro-grid energy scheduling optimization is a complex nonlinear problem. During the studies, micro-grid low-voltage system whose resistance of transmission line plays an important role in system. Difference traditional control scheme, new scheme proposed which power flow each taken as decision variables, that to say, controlled order get optimal operating cost micro-grid. Based on above, this paper we focus scheduling. It formulated quadratic programming problem with constraints, due...

10.23919/ccc50068.2020.9189579 article EN 2020-07-01

Abstract Stimulating collagen production in skin helps to enhance vitality while decelerating aging- associated processes tissue. However, current approaches enhancing are commonly limited by accompanying pain and trauma. Here, we report that mid-infrared modulation (MIMO) at an intensity of 70 mW/cm 2 promotes human or mouse vivo without generating excessive heat. We found protein levels the collagen- degrading endopeptidase, MMP-1, were decreased mice following MIMO treatment, whereas...

10.1101/2024.03.28.587170 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-03-29
Coming Soon ...