A5101721716- Sugarcane Cultivation and Processing
- Biofuel production and bioconversion
- Natural Products and Biological Research
- Enzyme Structure and Function
- Genomics, phytochemicals, and oxidative stress
- Genomics and Phylogenetic Studies
- Biochemical and Molecular Research
- Molecular Junctions and Nanostructures
- Parasites and Host Interactions
- Radiomics and Machine Learning in Medical Imaging
- Global Maternal and Child Health
- Bone fractures and treatments
- Plant Gene Expression Analysis
- Adipose Tissue and Metabolism
- Endometrial and Cervical Cancer Treatments
- Mollusks and Parasites Studies
- Global Health Workforce Issues
- Nitric Oxide and Endothelin Effects
- Remote Sensing and Land Use
- Chemical Synthesis and Analysis
- Glycosylation and Glycoproteins Research
- Peptidase Inhibition and Analysis
- Power Systems and Technologies
- Plant responses to water stress
- MRI in cancer diagnosis
Qingdao University of Technology
2024
Kunming University of Science and Technology
2024
First People's Hospital of Yunnan Province
2024
University of California, San Francisco
2011-2024
Shanghai Zhangjiang Laboratory
2024
Huazhong Agricultural University
2024
Yunnan Agricultural University
2009-2023
Anqing Normal University
2021
Xian Yang Central Hospital
2020-2021
Hebei Eye Hospital
2021
Abstract Results from the third nationwide cluster sampling survey on epidemiology of schistosomiasis in People’s Republic China, conducted by Ministry Health 2004, are presented. A stratified random technique was used, and 239 villages were selected 7 provinces where Schistosoma japonicum remains endemic. total 250,987 residents 6–65 years age included survey. Estimated prevalence rates Hunan, Hubei, Jiangxi, Anhui, Yunnan, Sichuan, Jiangsu 4.2%, 3.8%, 3.1%, 2.2%, 1.7%, 0.9%, 0.3%,...
Circular single-stranded DNA (ssDNA) viruses have been rarely found in fungi, and the evolutionary ecological relationships among ssDNA infecting fungi other organisms remain unclear. In this study, a novel circular virus, tentatively named Diaporthe sojae virus 1 (DsCDV1), was identified phytopathogenic fungus isolated from pear trees. DsCDV1 has monopartite genome (3185 nt size) encapsidated isometric virions (21-26 nm diameter). The comprises seven putative open reading frames encoding...
Nuclear factor erythroid 2-related 2 (Nrf2), the transcriptional master regulator of stress-induced antioxidant response, plays a key role in neuronal resistance to oxidative stress and glutamate-induced excitotoxicity. Nrf2-mediated neuroprotection is primarily conferred by astrocytes both vitro vivo, but little known about physiologic signals that regulate astrocytic Nrf2 signaling. Here, we report activity pathway brain fine-tuned through regulatory loop between neurons astrocytes:...
Objective To estimate the age-specific disability weight of chronic schistosomiasis japonica in China.Methods Between October 2004 and January 2005, residents from two schistosome-endemic counties were screened for Schistosoma japonicum infection using an enzyme-linked immunosorbent assay.Disability morbidity assessed seropositive individuals European quality life questionnaire with additional cognitive dimension (known as "EQ-5D plus") ultrasonography.The was estimated based on...
Karyotypes provide key cytogenetic information on the phylogenetic relationships and evolutionary origins in related eukaryotic species. Despite our knowledge of chromosome numbers sugarcane its wild relatives, composition evolution among species Saccharum complex have been elusive owing to polyploidy large chromosomes these Oligonucleotide-based painting has become a powerful tool studies especially for plant with chromosomes. We developed oligo-based probes all 10 officinarum (2n = 8x 80)....
Erianthus produces substantial biomass, exhibits a good Brix value, and shows wide environmental adaptability, making it potential biofuel plant. In contrast to closely related sorghum sugarcane, can grow in degraded soils, thus releasing pressure on agricultural lands used for production. However, the lack of genomic resources hinders its genetic improvement, limiting present study, we generated chromosome-scale reference genome fulvus Nees. The size estimated by flow cytometry was 937 Mb,...
The AP2/ERF transcription factor family is one of the most important gene families in plants and plays a vital role plant abiotic stress responses. Although Erianthus fulvus very genetic improvement sugarcane, there are few studies concerning genes E. fulvus. Here, we identified 145 genome. Phylogenetic analysis classified them into five subfamilies. Evolutionary showed that tandem segmental duplication contributed to expansion EfAP2/ERF family. Protein interaction twenty-eight proteins...
Abstract Background Wild sugarcane Saccharum spontaneum plants vary in ploidy, which complicates the utilization of its germplasm breeding. Investigations on cold tolerance relation to different ploidies S. may promote exploitation and accelerate improvement varieties. Results A hypoploid clone 12–23 (2n = 54) hyperploid 15–28 92) were analysed under stress from morphological, physiological, transcriptomic perspectives. Compared with 15–28, had lower plant height, leaf length, internode stem...
Nrf2 (nuclear factor [erythroid-derived 2]-like 2; the transcriptional master regulator of antioxidant stress response) is regulated through interaction with its cytoplasmic inhibitor Keap1 (Kelch-like ECH-associated protein 1), which under basal conditions targets for proteasomal degradation. Sequestosome 1 (SQSTM1)/p62–a multifunctional adapter that accumulates following autophagy inhibition and can serve as a diagnostic marker human autophagic vacuolar myopathies (AVMs)–was recently shown...
We used the RT-PCR technique and immunocytochemical methods to determine expression of endothelial nitric oxide synthase (eNOS) or neuronal (nNOS) in cortical collecting duct (CCD) rats on high-K+ diet. The microdissected CCDs rat kidney were lysed, was carried out using nNOS eNOS gene-specific primers. Southern analysis showed presence mRNA but not CCD. CCD further confirmed by light microscopy. polyclonal antibody studies isolated found that immunoreactivity present heterogeneous with...
Although robustly expressed in the disease-free (DF) breast stroma, CD36 is consistently absent from stroma surrounding invasive cancers (IBCs). In this study, we primarily observed expression adipocytes and intralobular capillaries within DF breast. Larger vessels concentrated interlobular regions lacked were instead marked by of CD31. When evaluated perilesional ductal carcinoma situ, a nonobligate IBC precursor, loss was more commonly lesions associated with subsequent IBC. Peroxisome...
The TM0935 gene of Thermotoga maritima encodes a tandem cystathionine-β-synthase (CBS) domain protein, with molecular weight 16,425 Da (residues 1–145) and calculated isoelectric point 5.1. shares distant sequence homology to the CBS inosine monophosphate dehydrogenase (IMPDH). domains are small intracellular modules unknown function mostly found in two or four copies within protein. Pairs dimerize form stable globular domain.1 IMPDH contains inserted loop TIM barrel structure its enzymatic...
With the aim of exploring usefulness spatial analysis in formulation a strategy for schistosomiasis japonica control different environmental settings, population-based database was established Dangtu county, China. This database, containing human prevalence at village level from 2001 to 2004, analyzed by directional trend supported with ArcGIS 9.0 select optimum predictive approach. Based on approach selected, strata were classified and distribution infection Schistosoma japonicum estimated....
A collaborative COS conversion of Hg
Astrocytes regulate excitatory synapse formation and surface expression of glutamate AMPA receptors (AMPARs) during development. Less is known about glial modulation NMDA (NMDARs), which mediate synaptic plasticity neuronal survival in a subunit- subcellular localization-dependent manner. Using primary hippocampal cultures with mature synapses, we found that the density NMDA-evoked whole-cell currents was approximately twice as large neurons cultured presence glia compared to alone. The...
Artificial bee colony (ABC) algorithm has attracted much attention and been applied to many scientific engineering applications in recent years. However, there are still some insufficiencies ABC such as poor quality of initial solution, slow convergence, premature, low precision, which hamper the further development application ABC. In order improve performance ABC, we first proposed a novel initialization method called search space division (SSD), provided high solutions. And then,...
The TM0665 gene of Thermotoga maritima encodes a pyridoxal 5′-phosphate dependent O-acetylserine sulfhydrylase (EC 4.2.99.8) with molecular weight 31,131 Da and calculated isoelectric point 9.5. (also known as cysteine synthase) catalyzes the last step in biosynthesis. enzyme β-replacement acetyl group O-acetyl-L-serine by sulfide to generate L-cysteine production acetate. Alternatively, can use thiosulfate instead yield S-sulfo-L-cysteine. Here, we report crystal structure determined using...
The TM1645 gene of Thermotoga maritima encodes a type II quinolic acid phosphoribosyltransferase (QAPRTase, NadC, EC 2.4.2.19), with molecular weight 30,048 Da (residues 1–273) and calculated isoelectric point 5.1. QAPRTase is ubiquitous in distribution has been isolated from mammalian liver brain, plants, bacteria. provides the de novo source nicotinate mononucleotide (NAMN) for NAD biosynthesis both prokaryotes eukaryotes.1, 2 catalyzes formation NAMN, carbon dioxide, pyrophosphate...
TM1464 encodes an indigoidine synthase A (IndA)-like protein from Thermotoga maritima, with a molecular weight of 31,595 Da (residues 1–285) and calculated isoelectric point 5.5. IndA is involved in the biosynthesis indigoidine, blue pigment first described Erwinia chrysanthemi implicated protection oxidative stress pathogenicity.1 present yeast, Candida elegans, Arabidopsis, most bacteria.2 Here, we report crystal structure determined using semiautomated high-throughput pipeline Joint...