A5019981482- Pharmacological Effects of Natural Compounds
- Insect Utilization and Effects
- Dermatology and Skin Diseases
- Probiotics and Fermented Foods
- Gut microbiota and health
- Fiscal Policy and Economic Growth
- Monetary Policy and Economic Impact
- Psoriasis: Treatment and Pathogenesis
- Hungarian Social, Economic and Educational Studies
- Polysaccharides and Plant Cell Walls
- Cancer Cells and Metastasis
- Herbal Medicine Research Studies
- 3D Printing in Biomedical Research
- Fiscal Policies and Political Economy
- Glycosylation and Glycoproteins Research
- Regional Economic and Spatial Analysis
- Natural product bioactivities and synthesis
- Angiogenesis and VEGF in Cancer
- Ginseng Biological Effects and Applications
- Exercise and Physiological Responses
- Rheumatoid Arthritis Research and Therapies
- Phytochemicals and Antioxidant Activities
- Viral gastroenteritis research and epidemiology
- Cancer Mechanisms and Therapy
- CRISPR and Genetic Engineering
Seoul National University
2016-2025
Dongseo University
2023-2024
Despite considerable efforts, mTOR inhibitors have produced limited success in the clinic. To define vulnerabilities of mTORC1-addicted cancer cells and to find previously unknown therapeutic targets, we investigated mechanism piperlongumine, a small molecule identified chemical library screen specifically target with hyperactive mTORC1 phenotype. Sensitivity piperlongumine was dependent on its ability suppress RUVBL1/2-TTT, complex involved chromatin remodeling DNA repair. Cancer high...
Removal of sugar moieties from ginsenosides has been proposed to increase their biological effects in various disease models. In order identify strains that can aglycone contents, we performed a screening using bacteria isolated the feces infants focusing on acid tolerance and β-glucosidase activity. We 565 selected Bifidobacterium animalis subsp. lactis LT 19-2 (LT 19-2), which exhibited highest activity with strong tolerance. As red ginseng (RG) known exert immunomodulatory functions,...
This study investigates the effects of government spending shocks on various key macro variables in China, Korea, and Japan using structural VAR models. The main empirical findings are as follows. Government multipliers all three countries far larger than 1 recent years. effectiveness fiscal expansion has not changed markedly China but substantially increased Korea (after Asian financial crisis) (during zero lower bound period). Increases associated with changes monetary exchange rate policy...
The composition of commensal bacteria plays a critical role in controlling immune responses the intestine. Studies have shown that specific bacterial strains may capacity to enhance host defense against gastrointestinal viral infections. While norovirus is known be most common cause gastroenteritis, leading an estimated 200,000 deaths every year, identification with protective effects infection remains elusive. Here, we discovered
Platycosides, major components of
Atopic dermatitis (AD) is a chronic inflammatory disease characterized by hyperactivated immune reactions in the skin. AD prevalent health concern developing countries, with particularly high incidence among children. Despite ongoing research on AD, prevention and treatment strategies for patients remain inadequate. In this study, inhibitory effects of Cornus walteri were investigated. C. (Cornaceae), commonly known as “Walter’s dogwood,” deciduous shrub used traditional medicine to treat...
This paper investigates the effects of government consumption shocks on various key macro variables for China, Korea and Japan, by using a structural VAR model.The main empirical findings are as follows.First, spending multipliers all three countries far larger than 1 in recent years.The multiplier is China Japan.The effectiveness fiscal expansion has not been changed but substantially (after Asian financial crisis) Japan.Second, exchange rate trade balance different across...
In this study, we examined physiological functions as a key material to develop cosmeceuticals using extracts of Lagerstroemia macrocarpa Wall. Ex Kurz (L. macrocarpa). Initially, the L. extract was treated by different concentration and antioxidant assay (DPPH ABTS) were performed measure free radical scavenging ability. cytotoxicity experiment, into human epidermal keratinocytes with concentrations cytotoxicity. We found that induces differentiation markers such keratin (KRT)1, KRT2, KRT9,...