A5101874501- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Intraocular Surgery and Lenses
- Acute Ischemic Stroke Management
- Glaucoma and retinal disorders
- Medical Imaging and Analysis
- Bone Metabolism and Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Ocular Surface and Contact Lens
- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Selenium in Biological Systems
- Macrophage Migration Inhibitory Factor
- Frailty in Older Adults
- Mast cells and histamine
- Scoliosis diagnosis and treatment
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Catalytic Cross-Coupling Reactions
- Ethics in Clinical Research
- Retinal and Macular Surgery
- Cytokine Signaling Pathways and Interactions
- Apelin-related biomedical research
- Total Knee Arthroplasty Outcomes
First Affiliated Hospital of Guangzhou University of Chinese Medicine
2025
Guangzhou University of Chinese Medicine
2020-2025
Henan University of Science and Technology
2023-2024
Chinese PLA General Hospital
2020-2023
PLA Academy of Military Science
2022-2023
Chinese People's Liberation Army
2018-2022
Shanghai East Hospital
2020
Hainan Branch of People's Liberation Army General Hospital
2018
Kyushu University
2008-2013
Tokushima University
2009
We previously achieved NHC-mediated preparation of ester-type fluoroalkene dipeptide isosteres (ES-FADIs, 4) by an intramolecular redox reaction. In the present study, a cyanide ion-mediated reaction was successfully applied to conversions γ,γ-difluoro-α,β-enoylsilane 1 or 2 amide-type (AM-FADIs, 5 6). The use catalytic ion allowed synthesis chiral auxiliary incorporated FADI 15b which then subjected diastereoselective α-alkylation yield α-substituted FADIs 17. Furthermore, presented...
Abstract Frailty and hypertension often coexist are increasingly prevalent with advancing age. Although is independently associated frailty, whether high blood pressure variability affecting frailty unclear. In this retrospective study, we consecutively enrolled elderly patients essential undergoing 24‐hour ABPM. The was assessed by a 38‐item index. parameters of ABPM, including ARV, coefficient CV, SD, weighed SD were calculated. Ordinal logistic regression used to investigate the...
Posterior capsule opacification (PCO) is one of the most frequent late-onset complications after cataract surgery. Several kinds drug-eluting intraocular lenses (IOL) were designed for sustainable drug release to suppress ocular inflammation, proliferation lens epithelial cells (LECs) and development PCO Despite previous advances in this field, drug-loaded IOLs limited toxicity, insufficient drug-loading capacity, short time. To prevent address these drawbacks, a novel IOL (Rapa@Ti3C2-IOL),...
To evaluate visual acuity (VA) and refractive status in patients with cataract irregular astigmatism a regular central component after phacoemulsification implantation of toric intraocular lens (IOL). Patients associated were enrolled. All underwent IOL implantation. Postoperative acuity, residual astigmatism, rotation, higher-order aberration, objective subjective quality measured 3 months surgery. Twenty-three eyes included the study. The logMAR corrected uncorrected distance values...
Abstract Background Polymethylmethacrylate (PMMA) is commonly used for cement-augmented pedicle screw instrumentation (CAPSI) to improve the fixation stability and reduce risk of loosening in osteoporotic thoracolumbar spine. Biomechanical researches have shown that various dose cement (1-3 ml) can be injected enhance stability. To date, there been no studies on relationship between adjacent segment degeneration volume PMMA. This study aimed explore influence CAPSI with different volumes...
Posterior capsular opacification (PCO) is the most common complication of cataract surgery. In this study, we develop a model to quantitatively predict probability Nd:YAG laser capsulotomy for vision-threatening PCO improve life quality postoperative patients. A registry analysis procedures performed between years 2010 and 2021. Following screening 16,802 patients (25,883 eyes), 9768 (eyes) were enrolled. The cohort was randomly divided into two groups: training (n = 6838) validation 2930)....
To establish a comprehensive treatment strategy and evaluate the efficacy of combination anti-vascular endothelial growth factor (VEGF) injection, pars plana vitrectomy (PPV), endoscopic pan-retinal photocoagulation (PRP), cyclophotocoagulation (ECP) surgery for neovascular glaucoma (NVG) patients.This retrospective study included 30 patients (30 eyes) who were suffering from NVG treated with PPV & PRP ECP (ECP group, 16 eyes), or Ahmed valve implantation (Ahmed 14 eyes). The intraocular...
As one of the severe complications diabetes mellitus, diabetic retinopathy (DR) is leading cause blindness in working age worldwide. Although panretinal photocoagulation (PRP) was standard treatment, PRP-treated DR still has a high risk progression. Hence, this study aimed to assess factors and establish model for predicting worsening (DR-worsening) within five years after PRP.Patients who were diagnosed with non-proliferative or proliferative treated PRP included, those patients randomly...
To present the application and efficacy of marsupialization for treatment conjunctival inclusion cyst in Stevens-Johnson syndrome. Retrospective case study four patients (five eyes) presenting with cysts aftermath syndrome, whom two were male female, one had bilateral remaining three unilateral ones. The all treated by fornix reconstruction rather than excising it. After operation, sacs deepened average depth was 4.0 mm. Follow-ups which ranged from 7 months to 3 years (19 on average, median...
Objective To assess the changes in IOL-Master 700 parameters after administering sodium hyaluronate eye drops to moderate and severe dry non-dry patients. Methods Non-randomized controlled clinical research was performed.Patients with non were enrolled this study, 40 patients each group.All underwent bioassay before 5, 10 15 minutes administration of 0.1% drops.The differences axial length (AL), central corneal thickness (CCT), curvature, intraocular lens (IOL) compared...
Abstract Background: Polymethylmethacrylate (PMMA) is commonly used for cement-augmented pedicle screw instrumentation (CAPSI) to improve the fixation stability and reduce risk of loosening in osteoporotic thoracolumbar spine. Biomechanical researches have shown that various dose cement (1-3ml) can be injected enhance stability. To date, there been no studies on relationship between adjacent segment degeneration volume PMMA. This study aimed explore influence CAPSI with different volumes...
Abstract Background: Polymethylmethacrylate (PMMA) is commonly used for cement-augmented pedicle screw instrumentation (CAPSI) to improve the fixation stability and reduce risk of loosening in osteoporotic thoracolumbar spine. Biomechanical researches have shown that various dose cement (1-3ml) can be injected enhance stability. To date, there been no studies on relationship between adjacent segment degeneration volume PMMA. This study aimed explore influence CAPSI with different volumes...
Abstract Background: Polymethylmethacrylate (PMMA) is commonly used for cement-augmented pedicle screw instrumentation (CAPSI) to improve the fixation stability and reduce risk of loosening in osteoporotic thoracolumbar spine. Biomechanical researches have shown that various dose cement (1-3ml) can be injected enhance stability. To date, there been no studies on relationship between adjacent segment degeneration volume PMMA. This study aimed explore influence CAPSI with different volumes...
Abstract Background Diabetic retinopathy (DR) as one of the severe complications diabetes mellitus is leading cause blindness in working age worldwide. While DR still has a high risk progression after panretinal photocoagulation (PRP) treatment. Hence, this study aims to assess factors and established model for predicting worsening diabetic (DR-worsening) within 5 years PRP. Methods Patients who were diagnosed with non-proliferative or proliferative treated PRP included randomly assigned...
Abstract Background: Coronavirus disease 2019 (COVID-19) has generated an unprecedented clinical research response, but the data about characteristics of COVID-19-related studies were scarce. The study aimed to describe registered at ClinicalTrials.gov and further identify factors affecting recruitment completeness these studies. Methods: extracted 5,672 included 5,430 relating COVID-19 ClinicalTrials.gov. We presented all Identification risk for status was achieved using multiple logistic...