A5040865430- Nonmelanoma Skin Cancer Studies
- Cutaneous Melanoma Detection and Management
- Cancer and Skin Lesions
- Dermatologic Treatments and Research
- Immunotherapy and Immune Responses
- Cutaneous lymphoproliferative disorders research
- Hedgehog Signaling Pathway Studies
- Bartonella species infections research
- Melanoma and MAPK Pathways
- Cancer Genomics and Diagnostics
- Skin Protection and Aging
- melanin and skin pigmentation
- Reconstructive Facial Surgery Techniques
- Streptococcal Infections and Treatments
- DNA Repair Mechanisms
- Viral Infections and Vectors
- CAR-T cell therapy research
- Autoimmune Bullous Skin Diseases
- Body Contouring and Surgery
- Rabies epidemiology and control
- RNA Interference and Gene Delivery
- Hair Growth and Disorders
- Oral Health Pathology and Treatment
- Nail Diseases and Treatments
- Cancer Immunotherapy and Biomarkers
Universidade Estadual de Campinas (UNICAMP)
2014-2024
Committee on Publication Ethics
2024
Hospital de Clínicas da Unicamp
2002-2020
Malama Learning Center
2015
Universidade Estadual Paulista (Unesp)
2009
University Dermatology
2007
Abstract Background Stretch marks or striae distensae (SD) can be considered a common skin disorder, but their physiopathogenic mechanisms have not been totally clarified. Although it is an esthetic complaint, may serious psychosocial consequences besides the local and systemic alterations of conjunctive tissue. This study aims at assessing quantifying estrogen, androgen glucocorticoid receptors in samples with comparing normal skin. Methods Skin for biopsy were obtained from eight patients...
Bartonella henselae is the agent of cat scratch disease and bacillary angiomatosis. Blood donors can be asymptomatic carriers B. risk for transmission by transfusion should considered. The objective this study was to demonstrate that remains viable in red blood cell (RBC) units at end storage period. Two RBC were split into two portions. One portion inoculated with other used as a control. All stored 4 degrees C 35 days. Aliquots collected on weekly basis culture dish chocolate agar, ideal...
A large number of diseases may cause Atrophic skin disorders are caused by a diseases, some them idiopathic and others inflammatory, in which there is loss volume body segments. Localized scleroderma rare inflammatory dermatosis, manifested atrophic subcutaneous tissue alterations. Lipoatrophy be genetically inherited or acquired as result panniculitis, HIV infections aging. Many treatments have been proposed. Results vary the acute phase scarce when sclerosis atrophy already established....
Summary This study aimed to evaluate whether PD1.1 (c.‐606G>A), PD1 (c.627 + 252C>T), PD1.5 (c.804C>T), and PD1.9 (c.644C>T) single nucleotide polymorphisms of PDCD1 gene influence the risk, clinicopathological aspects, survival cutaneous melanoma (CM). Individuals with phototype I or II CC genotype were under 5.89‐fold increased risk developing CM. TT expression (2.49 versus 1.28 arbitrary units, p = .03) CT allele T in TCD4 lymphocytes (16.6 12.5%, .01; 17.0 13.1%, .006). At 60...
Xeroderma pigmentosum is a rare autosomal recessive genetic disease characterized by extreme sensitivity due to solar radiation and deficiency in excision repair DNA. Those factors promote set of skin abnormalities such as keratosis, hyperpigmentation, tumors areas exposed sunlight, ocular and, eventually, neurological disorders. In the present review, we summarize main clinical features related case xeroderma man who was not diagnosed until he 45 years old.
Non-melanoma skin cancer is the most common type of malignancy in Western world, and surgical excision preferred approach. The approach adopted face incomplete excisions basal cell carcinoma still controversial. To compare number tumor recurrences after treatment for incompletely excised carcinoma. Selection statistical analysis medical records patients who had compromised margins a tertiary hospital from 2008 to 2013. A total 120 were analyzed; mean age was 69.6 years, 50% female. prevalent...
FUNDAMENTOS: A observação de lesões cutâneas é freqüente pelos indivíduos que as têm e por seus familiares. demanda pacientes buscam atenção médica com queixas significante. OBJETIVO: Determinar a freqüência das alterações dermatológicas em usuários do Sistema Único Saúde Campinas, Estado São Paulo, Brasil. MÉTODOS: Cinco unidades básicas saúde foram selecionadas pela Secretaria da Prefeitura Municipal para participar pesquisa. Todos os atendidos profissionais dessas unidades, no período 20...
Lentigo maligna (LM) is a common melanocytic malignancy which requires therapy because of the risk progression to invasive lentigo melanoma much worse prognosis.18 patients with clinical and histopathological diagnosis LM were treated cryosurgery. The older Caucasians (mean age 59.5 years) 11 male. They chosen for cryosurgery lesion posed surgical challenge or patient was not good candidate. two freeze-thaw cycles liquid nitrogen under local anesthesia in single sitting. Lesions larger than...
Background: Keratoacanthoma (KA) is easily confused with squamous cell carcinoma (SCC) on a clinical or histopathologic basis. However, KA undergoes spontaneous regression, whereas SCC does not. Objective: Our objective was to study the features associated regression in KA-like lesions support therapeutic option. Methods: Forty-three biopsies of were taken at patient admission. One month later, surgical excision performed 18 growing lesions. Regressing left untreated. Classic and diagnosis...
Differential diagnosis between keratoacanthoma (KA) and squamous cell carcinoma (SCC) is difficult due to their similarities. The mechanisms that drive distinct biological behavior are poorly understood. To investigate whether the assessment of microvessel density (MVD) could be helpful in KA SCC differential gain insight into pathogenesis KA-like neoplasms, we compared CD105- CD34-stained vessels KAs SCCs relation expression p53 oncoprotein proliferation marker Ki67. This an observational...
A criocirurgia com nitrogênio líquido é recurso cirúrgico utilizado para o tratamento de várias lesões cutâneas, benignas, pré-malignas e malignas. Promove destruição dos tecidos acometidos por congelamento alterações da resposta imunológica. Os autores enfocam a utilização no das dermatoses infecciosas, principalmente as verrugas virais, leishmaniose ccromoblastomicose. Discutem os resultados como primário ou coadjuvante. O artigo também apresenta cuidados instrumentos doenças infecciosas.
Background Chronic telogen effluvium (CTE), a poorly understood condition, can be confused with or may prodrome to female pattern hair loss (FPHL). The pathogenesis of both is related follicle cycle shortening and possibly blood supply changes. Aim To analyze number histomorphometric immunohistochemical findings through vascular endothelial growth factor (VEGF), Ki-67, CD31 immunostaining in scalp biopsies 20 patients CTE, 17 mild FPHL 9 controls. Methods Ki-67 index VEGF optical density...
Cryosurgery is an efficient therapeutic technique used to treat benign and malignant cutaneous diseases. The primary active mechanism of cryosurgery related vascular effects on treated tissue. After a cryosurgical procedure, exuberant granulation tissue formed at the injection site, probably as result angiogenic stimulation cryogen inflammatory response, particularly in endothelial cells.To evaluate freezing, part phenomenon healing rat skin subjected previous injury.Two incisions were made...
A intradermoterapia é um procedimento médico introduzido por Pistor, em 1958, e consiste na aplicação, diretamente região a ser tratada, de injeções intradérmicas substâncias farmacológicas muito diluídas. Esse método capaz estimular o tecido que recebe os medicamentos tanto pela ação da punctura quanto dos fármacos, apregoa-se sua vantagem evitar uso medicação sistêmica. Há relatos utilização para tratamento doenças dolorosas, dermatoses condições consideradas inestéticas. Atualmente,...
Mohs micrographic surgery is a specialized surgical procedure used to treat skin cancer. The purpose of this study was better understand the profile patients who underwent and determine how histology might be related complications number stages required for complete removal.The records from October 2008 November 2013 at Dermatology Division Hospital Campinas University were assessed. variables included gender, age, anatomical location, histology, complications.Contingency tables compare with...