Whole-brain voxel-based unbiased resting state functional connectivity was analysed in 418 subjects with autism and 509 matched typically developing individuals. We identified a key system the middle temporal gyrus/superior sulcus region that has reduced cortical (and increased medial thalamus), which is implicated face expression processing involved social behaviour. This ventromedial prefrontal cortex, emotion communication. The gyrus also theory of mind processing. second...

Dynamic reconfiguration of the human brain is characterized by nature complexity. The purpose this study was to measure such complexity and also analyze its association with age. We modeled dynamic process functional connectivity, which established resting-state magnetic resonance imaging (fMRI) data, we measured within connectivity sample entropy (SampEn). A brainwide map SampEn in healthy subjects shows larger values caudate, olfactory gyrus, amygdala, hippocampus, lower primary...

Neuronal excitabilities behave as the basic and important dynamics related to transitions between firing resting states, are characterized by distinct bifurcation types spiking frequency responses. Switches class I II induced modulations outside neuron (for example, modulation M-type potassium current) have been one of most concerning issues in both electrophysiology nonlinear dynamics. In present paper, we identified switches 2 classes excitability responses when an autapse, which widely...

The transition from chaotic bursting to spiking has been simulated and analyzed in theoretical neuronal models. In the present study, we report experimental observations a neural pacemaker of within bifurcation scenario period-1 spiking. This was induced by adjusting extracellular calcium or potassium concentrations. began period-doubling bifurcations period-adding sequences pattern. is characterized alternations between multiple continuous spikes long duration quiescence, whereas comprised...

In contrast to traditional viewpoint that positive feedback current always enhances neural firing activities, in the present paper, we identify excitatory mediated by memristor can induce negative responses of bursting patterns, which be well interpreted with bifurcations. For Hindmarsh–Rose neuron model without memristor, period-adding bifurcations patterns and increase frequency induced increasing effect background current. After introducing a simulate biological synapse or electromagnetic...

Recent experimental observations on seizures showed that the optogenetic activation of inhibitory interneurons cannot suppress but enhance frequency and synchronization spiking excitatory pyramidal neurons, i.e., synchronized post-inhibitory rebound (PIR) spiking. This complex phenomenon presents paradoxical functions novel etiologies seizures. In present study, nonlinear mechanisms conditions PIR are obtained in a network model neurons. Pyramidal neurons with low near bifurcation,...

Enhanced activity of inhibitory neurons, which is often used to suppress behaviors pyramidal neurons treat brain diseases, whereas can enhance spiking a mixed-mode bursting (MMB) in recent experiments on migraine and seizure. The MMB contains phase with high level membrane potential/extracellular potassium concentration ([K+]o), propagate form spreading depolarization (SD) wave. Different from the common view that MMB/SD induced by enhanced positive effect or [K+]o, present paper, dynamics...

The inhibitory synapse can induce synchronous behaviors different from the anti-phase behaviors, which have been reported in recent studies. In present paper, are investigated motif model composed of reciprocal coupled neurons with endogenous bursting and time delay. When coupling strength is weak, behavior appears at a single interval delay within period. strong, multiple appear intervals patterns delays strengths that be well interpreted by dynamics pattern isolated neuron, acquired...

Some chaotic and a series of stochastic neural firings are multimodal. Stochastic multimodal firing patterns special importance because they indicate possible utility noise. A number previous studies confused the dynamics patterns. The confusion resulted partly from inappropriate interpretations estimations nonlinear time measures. With deliberately chosen examples present paper introduces strategies methods identification ones. Aided by theoretical simulation we show that result effects...

An unnoticed chaotic firing pattern, lying between period-1 and period-2 patterns, has received little attention over the past 20 years since it was first simulated in Hindmarsh-Rose (HR) model. In present study, rat sciatic nerve model of chronic constriction injury (CCI) used as an experimental neural pacemaker to investigate transition regularities spontaneous patterns. Chaotic firings observed located four bifurcation scenarios different, isolated pacemakers. These were induced by...

The chaotic spiking and intermittent bursting were observed from biological experiment on a neural pacemaker. manifested alternation between phase of nearly period-3 another irregular bursting, exhibited nonsmooth-like structure in the first return map interspike interval (ISI) series. smooth structure. simulated Chay model identified by dissection fast-slow variables. structures both ISI slow variable, while structures. different scale laws averaged length periodic with respect to changes...

Different stochastic neural firing patterns or rhythms that appeared near polarization depolarization resting states were observed in biological experiments on three nervous systems, and closely matched those simulated bifurcation points between stable equilibrium point limit cycle a theoretical model with noise. The distinct dynamics of spike trains interspike interval histogram (ISIH) these identified found to build relationship the coexisting behaviors fixed frequency four different types...