A5062733415- Blood donation and transfusion practices
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Restless Legs Syndrome Research
- Uterine Myomas and Treatments
- Maternal and fetal healthcare
- Reproductive Health and Contraception
Sanquin
2020-2025
Public Health Service of Amsterdam
2023-2024
Amsterdam University Medical Centers
2020-2024
Amsterdam UMC Location University of Amsterdam
2023-2024
National Institute for Public Health and the Environment
2020
University of Amsterdam
2020
The world is combating an ongoing COVID-19 pandemic with health-care systems, society and economies impacted in unprecedented way. It unclear how many people have contracted the causative coronavirus (SARS-CoV-2) unknowingly are asymptomatic. Therefore, reported cases do not reflect true scale of outbreak. Here we present prevalence distribution antibodies to SARS-CoV-2 a healthy adult population Netherlands, which highly affected country, using high-performance immunoassay. Our results...
Abstract The world is combating an ongoing COVID-19 pandemic 1-4 . Health-care systems, society and the economy are impacted in unprecedented way. It unclear how many people have contracted causative coronavirus (SARS-CoV-2) unknowingly. Therefore, reported cases do not reflect true scale of outbreak 5-9 Natural herd immunity has been suggested as a potential exit strategy during outbreaks, which may arise when 50-67% community infected 10 Here we present prevalence distribution antibodies...
ABSTRACT BACKGROUND Regular blood donation is associated with an increased risk of iron deficiency (ID; ferritin <15 µg/L). Oral supplementation known to shorten store recovery time and could serve as a more effective alternative extended intervals. We aimed determine the optimal ferritin-guided protocol in terms donor health, side-effects, return, treatment adherence. METHODS In this prospective randomized placebo-controlled trial donors levels ≤30 µg/L were enrolled study randomly...
Abstract Introduction To prevent blood donors from developing iron deficiency (ferritin <15 μg/L) and subsequent anemia (hemoglobin <120 g/L), services rely on information about known risk factors, including the donor's sex age. For example, while Finnish women are able to donate whole with a minimum donation interval of 91 days, in 18 25‐year‐old age group recommended no more than once per year. Menstrual loss is not accounted for recommendations, despite being factor deficiency. We...
Abstract Introduction Whole blood donors are at increased risk for iron deficiency (ID). ID anemia is associated with several symptoms, such as fatigue, cognitive dysfunction, pica, and restless leg syndrome (RLS). However, it unclear if these symptoms also occur when a donor has developed without anemia. This study aims to determine whether non‐anemic (NAID) the occurrence of ID‐related symptoms. Study Designs Methods We combined data from three studies in whole (i.e., Donor Insight‐III,...
Background Frequent whole blood donors have an increased risk of developing iron deficiency. Iron deficiency can detrimental health effects when left untreated. Donation intervals are commonly too short to replenish stores and extending these reduces donor availability. Oral supplementation is known shorten store recovery time but may also induce gastrointestinal complaints. We aim optimise the effectiveness supplements while minimising risks side effects. Therefore, we will evaluate impact...
Abstract Background and Objectives Iron supplementation is an effective strategy to mitigate donation‐induced iron deficiency in blood donors. However, evidence on the perception of individuals involved donation as a service policy lacking. This study aimed evaluate knowledge whole donors (donors), collection staff (collection staff) donor physicians (physicians) regarding loss supplementation. Materials Methods Online focus group discussions had four six participants followed structured...
Abstract Background and Objectives Blood donors are at risk of developing iron deficiency (ID) (ferritin <15 μg/L, World Health Organization definition). services implement different strategies to mitigate this risk. Although in Finland group‐based supplementation is place, no provided the Netherlands. We aim describe differences ferritin levels ID prevalence donor general populations these countries. Materials Methods Six cohorts, stratified based on sex, for women age, Netherlands were...
Abstract Background and Objectives Regular whole blood donations are associated with an increased risk of iron deficiency. Iron supplementation is effective strategy to prevent donation‐induced However, research on donor perceptions towards such a policy limited. Therefore, we aim evaluate donors' knowledge depletion their regarding as service policy. Materials Methods Three thousand Dutch donors were invited complete survey assessing attitudes Linear regression modelling was used...