Micheline Freire Donato

ORCID: 0000-0003-0841-442X
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About
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Research Areas
  • Psychedelics and Drug Studies
  • Venomous Animal Envenomation and Studies
  • Cannabis and Cannabinoid Research
  • Biochemical and Structural Characterization
  • Cardiovascular and exercise physiology
  • Phytochemistry Medicinal Plant Applications
  • Agricultural and Food Sciences
  • Insect and Pesticide Research
  • Meta-analysis and systematic reviews
  • Trypanosoma species research and implications
  • Bioactive Natural Diterpenoids Research
  • Lipid Membrane Structure and Behavior
  • Blood Pressure and Hypertension Studies
  • Synthesis and Biological Evaluation
  • Healthcare Regulation
  • Toxin Mechanisms and Immunotoxins
  • Biotechnology and Related Fields
  • Ziziphus Jujuba Studies and Applications
  • Phytochemistry and Bioactivity Studies
  • Physical Activity and Health
  • Neuroscience and Neuropharmacology Research
  • Research on Leishmaniasis Studies

Universidade Federal da Integração Latino-Americana
2023

Universidade Federal de São Carlos
2023

Universidad Latina
2023

Universidade Federal da Paraíba
2011-2021

Acute chagasic encephalitis is a clinically severe central nervous system (CNS) manifestation. However, the knowledge of form Chagas disease incomplete. The role muscarinic acetylcholine receptor (mAChR) on mice behavior and brain lesions induced by Trypanosoma cruzi (Colombian strain) was herein investigated in treated with mAChR agonist antagonist (carbachol atropine), respectively. Immunosuppressed or non-immunosuppressed were intracerebroventricularly (icv) intraperitoneally (ip)...

10.3390/pathogens10020121 article EN cc-by Pathogens 2021-01-25

Aim: In the process of aging, there is a decrease on muscle strength and cognitive function. Resistance training combined with blood flow restriction (BFRRT) has been shown capable maintaining or improve aspects physical health. However, effects BFRRT function elderly are not clear. This study aimed to describe design randomized controlled clinical trial, that will investigate function, performance physiological morphological in women. Methods: Forty participants be into one following...

10.1590/s1980-657420210016220 article EN cc-by Motriz Revista de Educação Física 2021-01-01

As peçonhas de serpentes são uma mistura complexa componentes proteicos e não-proteicos, cujas proteínas peptídeos correspondem 90-95% da peçonha. O vasto arsenal bioquímico presente nessas possui moléculas que podem afetar diversas funções biológicas, com grande especificidade seletividade, em diferentes alvos farmacológicos (receptores, canais iônicos, enzimas). Como resultado, essas têm sido cada vez mais utilizadas como protótipos para o desenvolvimento fármacos medicamentos. exemplo,...

10.34119/bjhrv4n6-001 article PT Brazilian Journal of Health Review 2021-11-03

The trajectory of medicinal Cannabis in Brazil began academia the 1970s, when Dr. Carlini published first non-clinical study on rodents showing bioprospecting cannabidiol (CBD) as an anticonvulsant agent.Decades later, 2014, gained visibility with case girl Anny Fischer, who suffered from a rare and serious illness, allowing family to gain authorization import extracts containing high CBD low delta-9-tetrahydrocannabinol.(THC) (> 0.2 mg).In United States, modern industry is almost three...

10.22533/at.ed.81338232209 article EN International Journal of Biological and Natural Sciences 2023-08-31

The trajectory of medicinal Cannabis in Brazil began academia the 1970s, when Dr. Carlini published first non-clinical study on rodents showing bioprospecting cannabidiol (CBD) as an anticonvulsant agent.Decades later, 2014, gained visibility with case girl Anny Fischer, who suffered from a rare and serious illness, allowing family to gain authorization import extracts containing high CBD low delta-9-tetrahydrocannabinol.(THC) (> 0.2 mg).In United States, modern industry is almost three...

10.22533/at.ed.813382322098 article EN International Journal of Biological and Natural Sciences 2023-08-31

The trajectory of medicinal Cannabis in Brazil began academia the 1970s, when Dr. Carlini published first non-clinical study on rodents showing bioprospecting cannabidiol (CBD) as an anticonvulsant agent.Decades later, 2014, gained visibility with case girl Anny Fischer, who suffered from a rare and serious illness, allowing family to gain authorization import extracts containing high CBD low delta-9-tetrahydrocannabinol.(THC) (> 0.2 mg).In United States, modern industry is almost three...

10.22533/at.ed.8133823300810 article EN International Journal of Biological and Natural Sciences 2023-08-31
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